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Researchers Reveal Safeguarding of a Key DNA Sensor in the Innate Immune System
Led by Qi Zhang, PhD, and Robert McGinty, MD, PhD, UNC-Chapel Hill scientists used cryo-electron microscopy technology to produce the first-ever high-resolution structure of the protein cGAS bound to the DNA packaging unit inside human cell nuclei, revealing how cGAS responds to foreign or damaged DNA, but not the body’s healthy DNA.
Located in News / 2020 / September
Strahl Lab Decodes Another Piece of the Histone Code Puzzle
In the journal Cell Reports, Brian Strahl, PhD, and colleagues engineered a genome regulator to reveal its important biological functions of genome access.
Located in News / 2020 / June
Hanna Trzeciakiewicz
Located in Images / PEOPLE / Impact Awards
UNC postdoctoral researcher joins international conversation on racism, for spotlight in Nature
Nikea Pittman, PhD, a structural biologist and postdoctoral fellow at the UNC School of Medicine, was featured in a Nature article that included insights from six black scientists from the United States and Europe.
Located in Vital Signs / 2020 / June 25