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Five genetic regions implicated in cystic fibrosis severity
An international consortium of researchers conducted the largest-ever CF genome-wide analysis to find new therapeutic targets.
Located in News / 2015 / September
Grateful for Every Breath
In 1990, Howell Graham was the first patient at UNC Hospitals with cystic fibrosis to receive a double lung transplant. Over the years he has tried several times, but couldn’t quite find the right words to say ‘thank you’ for the gift he received. Now, he says he’s finally ready.
Located in News / 2017 / February
Nurse leads research study to reduce needle sticks
Bedside nurse Nicoletta Constantin’s empathy for her patients has her leading a first-of-its-kind, nursing led research study to investigate a potential means to decrease the number of needle sticks cystic fibrosis patients endure with each inpatient admission.
Located in UNC Children's News / / CARE 2013 / Issue 2
The Family Disease
Cystic fibrosis took five of her siblings at a young age. Now, Wanda O’Neal, PhD, is part of a team of UNC researchers searching for reasons why. Their latest work has provided new insights that will help unravel why a sixth sibling with CF is living a productive life as he turns 50.
Located in News / 2015 / April
UNC researchers find unsuspected characteristics of new CF drugs, offering potential paths to more effective therapies
The study, led by Martina Gentzsch, PhD, provides evidence that could help drug developers improve compounds aimed at correcting CFTR proteins in cystic fibrosis patients.
Located in News / 2014 / July
Metabolomics Comes to UNC
A new resource helps researchers develop chemical signatures of health and disease.
Located in Vital Signs / 2014 / Feb. 20
Researchers further illuminate pathway for treatment of cystic fibrosis
New research findings from the UNC School of Medicine add further clarity to a question that has polarized the cystic fibrosis research community.
Located in News / 2016 / January
The Mechanism of Mucus: UNC discovery could lead to better cystic fibrosis treatments
University of North Carolina scientists found that mucin proteins, which make mucus thick and sticky, fail to unfold properly in the airways of people with cystic fibrosis. And they found the lack of water in the lung can trigger the misfolding mucins.
Located in News / 2017 / March
CF Foundation honors UNC researchers for vital treatment
Hypertonic saline, developed into an effective treatment at UNC School of Medicine in collaboration with Australian researchers, has become a proven therapy for thousands of people with cystic fibrosis.
Located in News / 2014 / October
Researchers pin down genetic pathways linked to CF disease severity
New findings from the UNC School of Medicine may shed light on why cystic fibrosis patients with the same genetic mutation can have different disease severity and may react differently to medications
Located in News / 2015 / February