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Five genetic regions implicated in cystic fibrosis severity
An international consortium of researchers conducted the largest-ever CF genome-wide analysis to find new therapeutic targets.
Located in News / 2015 / September
Scientists find gene linked to heightened mucus levels in lung disease
In lab experiments, UNC School of Medicine researchers showed that blocking the gene Bpifb1 led to a striking increase in the mucin protein MUC5B in mucus.
Located in News / 2017 / October
Cystic Fibrosis Discovery: Bacterial Burden Begins During First Years of Life
UNC School of Medicine scientists show that therapies to break up mucus in toddlers might offer the best route to a longer life for CF patients.
Located in News / 2018 / January
Are e-cigarettes ‘safer’ than regular cigarettes?
UNC School of Medicine researchers lead new study showing that e-cigarettes trigger unique and potentially damaging immune responses in human airways.
Located in News / 2017 / October
UNC lung researchers awarded $12.5-million NIH grant to develop new drug compounds
The National Institutes of Health has awarded four UNC experts a translational program project grant (tPPG) to develop and test therapeutics aimed at reducing the hyper-concentration of mucus often found in cystic fibrosis and asthma patients.
Located in News / 2017 / September
New simple test could help cystic fibrosis patients find best treatment
In a significant step toward personalized medicine for cystic fibrosis, a minimally-invasive technique developed in the lab of Martina Gentzsch, PhD, shows promise as a fast, inexpensive indicator to help more patients access new treatments.
Located in News / 2017 / November
A New Test to Measure the Effectiveness of CF Drugs
A new lab model developed by UNC’s Carla Ribeiro, PhD, and colleagues can be used to test new therapeutics for cystic fibrosis.
Located in News / 2017 / November
CF Foundation honors UNC researchers for vital treatment
Hypertonic saline, developed into an effective treatment at UNC School of Medicine in collaboration with Australian researchers, has become a proven therapy for thousands of people with cystic fibrosis.
Located in News / 2014 / October
Increased mucins pinned to worsening cystic fibrosis symptoms
The discovery from UNC School of Medicine researchers overturns a controversial research study and offers a path for creating and testing CF treatments.
Located in News / 2014 / June