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Phase I clinical trial shows promise as investigational drug for melanoma
Three of 15 patients with BRAF-mutant melanoma had partial responses to an investigational compound in an early-stage study led by UNC Lineberger's Stergios Moschos, MD.
Located in News / 2018 / February
Peanut allergy therapy proves effective during phase 3 clinical trial
Wesley Burks, MD, was a principal investigator on the phase 3 PALISADE trial to determine the efficacy of the AR101 oral immunotherapy developed by Aimmune Therapeutics for people allergic to peanuts.
Located in News / 2018 / February
New therapeutic gel shows promise against cancerous tumors
The lab of Zhen Gu, PhD, in the joint UNC-NC State biomedical engineering department developed a biodegradable hydrogel scaffold system to release chemotherapeutic and immunotherapeutic drugs at the tumor site.
Located in News / 2018 / February
Patient research advocates help scientists-in-training communicate findings more effectively
UNC Lineberger’s Patient Research Advocacy Group will help scientists and trainees to consider the patient perspective when conducting and presenting their research.
Located in Vital Signs / 2018 / Feb. 15
Researchers define structure, function of enzyme key to blood cancers
In the journal Nature, UNC Lineberger's Greg Wang, PhD, and colleagues reported findings about the structure and function of the DNMT3A enzyme complex, which helps control gene expression.
Located in News / 2018 / February
HIV exports viral protein in cellular packages
A study from the lab of UNC Lineberger's Dirk Dittmer, PhD, found that HIV sends out a protein called Nef in cellular packages called exosomes.
Located in News / 2018 / February
Scientists map molecular mechanisms crucial for new approach to heart disease therapy
Scientists led by UNC McAllister Heart Institute researcher Frank Conlon, PhD, reveal detailed molecular events underlying the transformation of ordinary fibroblast cells into therapeutic cardiac muscle cells.
Located in News / 2018 / February
UNC Researchers Identify Patterns of HIV Risk among People Who Inject Drugs in Vietnam
People who inject drugs in Vietnam are disproportionately affected by HIV. In an effort to combat new infections, researchers at UNC conducted the first study to explore how this population mixes together. Kumi Smith, PhD, a postdoctoral fellow at UNC’s Institute for Global Health & Infectious Diseases, is the study's lead author.
Located in Vital Signs / 2018 / Feb. 8
Gene therapy researchers find viral barcode to cross the blood-brain barrier
UNC School of Medicine scientists led by Aravind Asokan, PhD, reveal how certain gene-carrying AAV vectors can penetrate the brain more efficiently to treat brain and spinal cord conditions, while reducing liver payload.
Located in News / 2018 / February
Kids saying no to cigarettes are saying yes to vaping
In a study led by UNC Family Medicine’s Adam Goldstein, MD, researchers found that efforts are needed to help youth remain nicotine free – especially those adolescents who aren’t otherwise susceptible to smoking cigarettes.
Located in News / 2018 / February