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FDA Approves ZULRESSO™ (brexanolone) Injection for Postpartum Depression Following Three Clinical Trials Led by UNC Researcher
ZULRESSO, developed by Sage Therapeutics, is the first and only treatment specifically indicated to treat postpartum depression in women. UNC School of Medicine’s Samantha Meltzer-Brody, MD, MPH, was the principal investigator for three clinical trials showing rapid-reduction in depressive symptoms, and says the approval marks a major step forward in women’s healthcare.
Located in News / 2019 / March
Investigational Treatment for Postpartum Depression Consistently Reduced Symptoms Across Three Trials, Supporting Submission for FDA Approval
The findings of the integrated analysis from one phase 2 and two phase 3 pivotal trials were published today in The Lancet. Lead author Samantha Meltzer-Brody, MD, MPH, of the UNC School of Medicine said the promising results mark a major step forward in women’s health care.
Located in News / 2018 / August
UNC study: Tdap vaccine given during pregnancy reduces occurrence of infant pertussis
A study led by UNC’s Sylvia Becker-Dreps, MD, MPH, reviewed more than 675,000 pregnancies in the U.S. to determine if the Tdap vaccine given to a mother will reduce the chances of her child developing pertussis during the first 18 months of life. The results show a decrease in overall cases of pertussis, and most notably, in pertussis hospitalization in infants whose mothers were immunized during pregnancy.
Located in News / 2018 / June
Bae-Jump’s new research explores the origins of racial disparities in endometrial cancer
Victoria Bae-Jump, MD, PhD, was recently awarded grant funding totaling more than $800,000 to further her research on the underlying biological factors that may influence the development and mortality of endometrial cancer in both Caucasian and African-American women.
Located in News / 2018 / May
UNC researchers present study about family history and postpartum mental health at national APA Conference
Anna Bauer, PhD, and Samantha Meltzer-Brody, MD, MPH, were chosen by the APA to present findings from their recently published study about a new mother’s risk of postpartum psychiatric conditions when she has an immediate family member with a psychiatric disorder.
Located in News / 2018 / May
Pope Foundation donates $10 million to UNC-Chapel Hill
Carolina received a $10-million commitment from the John William Pope Foundation to provide support for the UNC Lineberger Comprehensive Cancer Center, UNC Horizons, the track and field program, and the Philosophy, Politics and Economics Program.
Located in News / 2018 / April
Hormone therapy could effectively prevent depression for some women in the menopause transition
Research conducted by Susan Girdler, PhD, and David Rubinow, MD, and published in JAMA Psychiatry, is the first to conclude that a year of hormone therapy can effectively prevent the onset of depressive symptoms for women during the menopause transition.
Located in News / 2018 / January
Online calculator estimates the impact of changes in breastfeeding rates on population health
The calculator will provide policy makers and advocates with an approximation of the return on investment for interventions that enable women to breastfeed.
Located in News / 2017 / September
Pregnant women should be included in Zika virus vaccine research, new guidance says
The inclusion of pregnant women in Zika virus vaccine research is crucial to solving the international health crisis, according to new guidance published by UNC’s Center for Bioethics and two other universities.
Located in News / 2017 / July
UNC researchers lead clinical trial evaluating potential treatment for postpartum depression
A phase 2, double-blind study of the investigational medication, brexanolone, in the treatment of women with severe PPD published in The Lancet. Clinical trials are currently underway at UNC.
Located in News / 2017 / June