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Researchers pin down genetic pathways linked to CF disease severity
New findings from the UNC School of Medicine may shed light on why cystic fibrosis patients with the same genetic mutation can have different disease severity and may react differently to medications
Located in News / 2015 / February
Scientists Reveal New Cystic Fibrosis Treatments Work Best in Inflamed Airways
New UNC School of Medicine research led by Martina Gentzsch, PhD, and Carla Ribeiro, PhD, suggests that cystic fibrosis drugs used to correct the faulty CFTR protein would work better when the patients’ airways are inflamed.
Located in News / 2018 / October
Students go silent for cystic fibrosis effort
Sister of former UNC Children's patient organizes social media campaign to raise awareness about cystic fibrosis following her sister's loss to the disease.
Located in UNC Children's News / News
The Family Disease
Cystic fibrosis took five of her siblings at a young age. Now, Wanda O’Neal, PhD, is part of a team of UNC researchers searching for reasons why. Their latest work has provided new insights that will help unravel why a sixth sibling with CF is living a productive life as he turns 50.
Located in News / 2015 / April
The Heart of a Researcher
At the UNC School of Medicine, researchers come to their work through various paths. For Wanda O'Neal, PhD, her tireless dedication to researching cystic fibrosis and lung conditions was born from a very personal place -- a family with six kids with CF.
Located in News / 2018 / May
The Mechanism of Mucus: UNC discovery could lead to better cystic fibrosis treatments
University of North Carolina scientists found that mucin proteins, which make mucus thick and sticky, fail to unfold properly in the airways of people with cystic fibrosis. And they found the lack of water in the lung can trigger the misfolding mucins.
Located in News / 2017 / March
UNC lung researchers awarded $12.5-million NIH grant to develop new drug compounds
The National Institutes of Health has awarded four UNC experts a translational program project grant (tPPG) to develop and test therapeutics aimed at reducing the hyper-concentration of mucus often found in cystic fibrosis and asthma patients.
Located in News / 2017 / September
UNC researchers find unsuspected characteristics of new CF drugs, offering potential paths to more effective therapies
The study, led by Martina Gentzsch, PhD, provides evidence that could help drug developers improve compounds aimed at correcting CFTR proteins in cystic fibrosis patients.
Located in News / 2014 / July
UNC School of Medicine researchers receive $9.96 million U.S. DoD grant
The US Department of Defense tabbed UNC Marsico Lung Institute researchers led by Richard Boucher, MD, and Ilona Jaspers, PhD, to study the adverse effects of inhaling toxic fumes from burn pits in the field.
Located in News / 2018 / December