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Scientists find a key protein that allows Plavix to conquer platelets

Scientists find a key protein that allows Plavix to conquer platelets

The findings could lead to more personalized approaches to controlling platelet activity during heart attacks and other vascular emergencies and diseases. Wolfgang Bergmeier, PhD, professor of biochemistry and biophysics, member of the McAllister Heart Institute at UNC, is senior author of the paper.

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Researchers pin down genetic pathways linked to CF disease severity

Researchers pin down genetic pathways linked to CF disease severity

New findings from the UNC School of Medicine may shed light on why cystic fibrosis patients with the same genetic mutation can have different disease severity and may react differently to medications

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UNC Lineberger-led study builds understanding of hepatitis C virus replication

UNC Lineberger-led study builds understanding of hepatitis C virus replication

Hepatitis C virus infection is a common cause of liver disease and of liver cancer in the United States. Through a new study that explores one aspect of how the virus hijacks host cell machinery to replicate itself, UNC Lineberger Comprehensive Cancer Center researchers have gained insight into the workings of a potential drug target for hepatitis C.

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Homes for Receptors

Homes for Receptors

Graduate student Kate Lansu searches for what activates orphan G protein-coupled receptors – a group of molecules that many scientists think could be good targets for new, more effective medications for a host of conditions, including chronic pain.

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The Gift of Transplant

The Gift of Transplant

David Gerber first witnessed the gift of transplant as a medical student. Today, as chief of abdominal transplant surgery at UNC Hospitals he performs transplant surgeries for patients and as a Lt. Col. in the Air Force Reserves serves as a valuable resource of transplant services for military families.

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R2d2 beats Mendel: scientists discover a selfish gene that breaks the ‘law of segregation’

R2d2 beats Mendel: scientists discover a selfish gene that breaks the ‘law of segregation’

The finding has implications for the field of evolutionary genetics and biomedical science, including new ways to research human conditions, such as Down syndrome.

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Cancer Survivor Becomes Ambassador for Hope

Cancer Survivor Becomes Ambassador for Hope

The latest installment in our Real Medicine video series features one of our Patient Ambassadors for North Carolina Children's Hospital.

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Bubonic Bottleneck: UNC scientists overturn dogma on the plague

Bubonic Bottleneck: UNC scientists overturn dogma on the plague

The current outbreak of the plague in Madagascar shines a light on the need for new approaches to treat the ancient pathogen. A new UNC study unexpectedly unravels a long-held theory on how a fleabite leads to infection.

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Largest ever genome-wide study on body fat and BMI strengthen genetic links to obesity

Largest ever genome-wide study on body fat and BMI strengthen genetic links to obesity

UNC researchers led by Karen Mohlke, PhD, and Kari North, PhD, including a consortium of researchers, find 89 new genetic locations that will help scientists pinpoint genes that play roles in different obesity traits.

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Epigenetic Breakthrough: A first of its kind tool to study the histone code

Epigenetic Breakthrough: A first of its kind tool to study the histone code

Scientists from UNC-Chapel Hill have created a new way to investigate epigenetic mechanisms important in diseases ranging from Alzheimer’s to cancers.

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Another breastfeeding benefit: preparing baby’s belly for solid food

Another breastfeeding benefit: preparing baby’s belly for solid food

A close examination of gut bacteria reveals that exclusively breastfed babies are better equipped for the transition to solids and potentially an early life with fewer stomach woes

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Creative Writing, Clinical Learning

Creative Writing, Clinical Learning

Second-year medical student Eric Tran blends passion for language, medicine, and serving the underserved.

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Potential pancreatic cancer treatment could increase life expectancy

Potential pancreatic cancer treatment could increase life expectancy

Device that drives drugs into solid tumors that are poorly vascularized opens the possibility of life-saving surgeries in cancer patients. James Byrne, PhD, a medical student and member of Joseph DeSimone’s lab, led the research by constructing the device and examining its ability to deliver chemotherapeutic drugs effectively to pancreatic cancer tumors, as well as two types of breast cancer tumors.

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Brain scans predict effectiveness of talk therapy to treat depression

Brain scans predict effectiveness of talk therapy to treat depression

UNC researchers lead first brain connectivity study pointing toward a new image-based diagnostic model – a roadmap to ensure patients receive the best treatment as quickly as possible. Gabriel S. Dichter, PhD, associate professor of psychiatry and psychology, is a senior author of the study.

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Simple strategies used by parents lead to improvements in one-year-olds at risk for autism spectrum disorder

Simple strategies used by parents lead to improvements in one-year-olds at risk for autism spectrum disorder

Parents using these strategies, known as Adapted Responsive Teaching (ART), reported significant improvements in their child’s sensory responsiveness, communication and socialization.

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In Good and Caring Hands

In Good and Caring Hands

Martin McCaffrey, MD, CAPT, USN (Ret), has taken the lessons he learned in the Navy and applied them to helping military families as they cope with the challenges of having a newborn in the Newborn Critical Care Center at UNC Hospitals.

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New deep-brain imaging reveals separate functions for nearly identical neurons

New deep-brain imaging reveals separate functions for nearly identical neurons

For the first time, UNC neuroscientist Garret Stuber, PhD, imaged activity patterns of individual brain cells in freely moving mice to link specific basic behaviors to particular neurons.

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UNC researcher co-leads effort to map genomic changes in head and neck cancer

UNC researcher co-leads effort to map genomic changes in head and neck cancer

A study co-led by a UNC Lineberger Comprehensive Cancer Center researcher has identified genomic changes in head and neck cancers linked to the sexually transmitted disease HPV -- the latest finding of a collaborative scientific effort designed to map out the genomic changes driving cancer.

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Parsing the Pathways

Parsing the Pathways

Graduate student Kathleen Mulvaney investigates the newly discovered interplay between two of the proteins that allow cells to divide.

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MRIs link impaired brain activity to inability to regulate emotions in autism

MRIs link impaired brain activity to inability to regulate emotions in autism

UNC researchers find that the bigger the differences in brain activity related to emotion regulation, the more severe the autism. Gabriel Dichter, PhD, associate professor of psychiatry and psychology was the paper's senior author.

MRIs link impaired brain activity to inability to regulate emotions in autism - Read More…