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UNC Lineberger discovery would allow researchers to fine-tune activity of cancer-hunting immune cells

UNC Lineberger discovery would allow researchers to fine-tune activity of cancer-hunting immune cells

Researchers led by UNC Lineberger’s Gianpietro Dotti, MD, reported new findings about the regulation of co-stimulatory molecules that could be used to activate cancer-killing immune cells – chimeric antigen receptor T-cells, or CAR-T. The molecules could also be used to decrease the activity of these cells.

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UNC Health Care Expands Services Available for Children in Wake County

UNC Health Care Expands Services Available for Children in Wake County

UNC Children’s Raleigh clinic and a new pediatrics wing at UNC REX Hospital will improve care for kids.

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Researchers Reverse HIV Latency, Important Scientific Step Toward Cure

Researchers Reverse HIV Latency, Important Scientific Step Toward Cure

Overcoming HIV latency – induction of HIV in CD4+ T cells that lay dormant throughout the body – is a major step toward creating a cure for HIV. For the first time, scientists at UNC-Chapel Hill, Emory University, and Qura Therapeutics – a partnership between UNC and ViiV Healthcare – have shown that a new approach can expose latent HIV to attack in two different animal model systems with little or no toxicity.

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Improving Cardiovascular Health of the Most Vulnerable

Improving Cardiovascular Health of the Most Vulnerable

Heart disease and stroke are major causes of pre-mature mortality and morbidity in North Carolina, and there are significant racial and geographic disparities in cardiovascular care, morbidity and mortality. A two-year pilot project led by Rick Stouffer, MD, shows how the cardiovascular health of the most vulnerable patients can be improved with free medications.

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Remembering Dr. Jeffrey Houpt

Remembering Dr. Jeffrey Houpt

Jeffrey L. Houpt, MD, Dean Emeritus of the UNC School of Medicine, and former CEO of UNC Health Care, passed away on January 13 at the age of 78.

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Katrina Donahue, MD, MPH, Appointed to the U.S. Preventive Services Task Force

Katrina Donahue, MD, MPH, Appointed to the U.S. Preventive Services Task Force

UNC Department of Family Medicine professor and vice chair of research, Katrina Donahue MD, MPH, has been appointed to the U.S. Preventive Services Task Force as one of its newest members.

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Researchers find clues to drug resistance in medulloblastoma subtype

Researchers find clues to drug resistance in medulloblastoma subtype

University of North Carolina Lineberger Comprehensive Cancer Center researchers led by Timothy Gershon, MD, PhD, and Kirk Wilhelmsen, MD, PhD, have new evidence to explain how drug resistance develops in a major subtype of medulloblastoma, the most common invasive brain tumor in children.

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A Full Breakdown of All Vaping Industry Academic Scholarships to High Schoolers

A Full Breakdown of All Vaping Industry Academic Scholarships to High Schoolers

Led by Adam Goldstein, MD, UNC Family Medicine researchers published details on how electronic cigarette companies offer academic scholarships to high school-age teenagers and young adults, showing a disconnect between the industry’s desire to increase vaping among young people and the desire of health advocates to decrease such usage.

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Life’s Clockwork: Scientist Shows How Molecular Engines Keep Us Ticking

Life’s Clockwork: Scientist Shows How Molecular Engines Keep Us Ticking

Charles Carter, PhD, published seminal work on the inner workings of chemical machines inside our cells that turn energy into action, the foundation of life.

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Remembering Dr. Robert Bashford

Remembering Dr. Robert Bashford

Dr. Robert Bashford, Associate Dean for Rural Initiatives and former Associate Dean for Admissions at the UNC School of Medicine, has passed away. Read a message from Drs. Wesley Burks and Cristy Page.

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The Ultimate Telemedicine: UNC Expert Helps Treat Astronaut’s Blood Clot During NASA Mission

The Ultimate Telemedicine: UNC Expert Helps Treat Astronaut’s Blood Clot During NASA Mission

Blood clot expert Stephan Moll, MD, professor of medicine in the UNC School of Medicine, consulted NASA on how to treat a U.S. astronaut’s deep vein thrombosis during a mission on the International Space Station. Moll co-wrote a case study on the successful treatment that has been published in the New England Journal of Medicine.

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Training Tomorrow’s Scientists: UNC’s BBSP at 12 Years Old

Training Tomorrow’s Scientists: UNC’s BBSP at 12 Years Old

With the number of applicants growing each year, UNC’s Biological and Biomedical Sciences Program (BBSP) has become a leader in introductory programs for students pursuing graduate degrees in the life and biomedical sciences. From lab rotations, wellness resources to career exploration opportunities, BBSP continues to train better students to become even better scientists.

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What Happens When Your Immune System and Antibiotics Don't Work together?

What Happens When Your Immune System and Antibiotics Don't Work together?

Research from the lab of Brian Conlon, PhD, shows that as the innate immune system attacks Staphylococcus aureus, the immune system also stops antibiotics from being able to efficiently kill. This antagonism may lead antibiotics to fail.

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Happy Holidays from Dr. Wesley Burks

Happy Holidays from Dr. Wesley Burks

Watch this Holiday greeting from Wesley Burks, MD, CEO of UNC Health Care and Dean of the UNC School of Medicine.

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First U.S. Study Shows Strong Results for Minimally Invasive Procedure to Treat Knee Pain from Osteoarthritis

First U.S. Study Shows Strong Results for Minimally Invasive Procedure to Treat Knee Pain from Osteoarthritis

Ari Isaacson, MD, director of clinical research in the UNC School of Medicine’s department of radiology, led a pilot study to investigate the effectiveness of using genicular artery embolization for long-term treatment of knee pain caused by osteoarthritis.

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Scientists Show How Tiny, Mutated Neuron Antennae Impair Brain Connectivity

Scientists Show How Tiny, Mutated Neuron Antennae Impair Brain Connectivity

UNC School of Medicine scientists led by Eva Anton, PhD, found that defective primary cilia can modulate connectivity between neurons during brain development and cause rare neurodevelopmental conditions called Joubert-syndrome related disorders.

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Scientists Visualize Competition Between Healthy, Dysfunctional Platelets

Scientists Visualize Competition Between Healthy, Dysfunctional Platelets

In some patients with blood disorders, platelet transfusion therapy doesn’t work. UNC School of Medicine scientists used real-time imaging and mouse models to show why. Their work, led by Wolfgang Bergmeier, PhD, could guide clinical studies and better use of platelet therapy.

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UNC School of Medicine Celebrates 2019-20 Yang Family Biomedical Scholars

UNC School of Medicine Celebrates 2019-20 Yang Family Biomedical Scholars

The award, which recognizes the research achievements of young tenured faculty, is made possible through a generous donation from Lenovo Chairman and CEO Yuanqing Yang with additional financial support from Mr. To Hing Wu. This is the fourth annual class of Yang Family Biomedical Scholars, and the recipients are Chad Pecot, Li Qian, Gregory Scherrer, Greg Wang.

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