In the journal Cell Reports, UNC Lineberger researchers report that when they removed Dicer from preclinical models of medulloblastoma, a common type of brain cancer in children, they found high levels of DNA damage in the cancer cells, leading to the cells’ death.
An Internet-based system for symptom collection benefited patients while giving them a clearer voice in their own care.
The new cancer drug delivery system improved efficacy of standard chemotherapy for ovarian cancer in mice with limited toxicity.
Findings suggest that radiologists studying mammograms observed suspicious markers that could have been indications of future cancer development.
The award, made possible through a donation from Lenovo chairman and CEO Yuanqing Yang, recognizes the research achievements of young tenured faculty.
UNC Lineberger-led study finds higher vitamin D and calcium intake does not reduce colorectal polyp risk
A UNC Lineberger-led study published in the New England Journal of Medicine found that vitamin D and calcium supplements do not reduce the risk of colorectal adenomas, which are benign tumors that can evolve into colorectal cancer.
From aspiring soccer star to world-renowned biochemist, Aziz Sancar, MD, PhD, joined Carolina’s other Nobel Laureate, Oliver Smithies, PhD, during a celebration of science at the UNC School of Medicine.
In the recent U.S. News and World Report rankings of America’s Best Hospitals, UNC Hospitals was nationally ranked in five of the 16 specialties. In this series, we profile these specialties to learn more about what makes them so outstanding.
Sancar’s team mapped DNA repair mechanisms that protect us against cancer.
The new drug-creation method could allow cancer drugs to last longer in the body to attack tumors, as well as cancer cells floating in the blood stream.
A science class captured Catherine Fahey’s imagination. A mother’s battle with cancer led her to pursue medicine as a career. At UNC, Fahey found a home at the junction of research and patient care.
When it comes to meeting the challenge of implementing new lung cancer screening guidelines, UNC is taking a multidisciplinary approach. Led by Daniel S. Reuland, MD MPH, Division of General Internal Medicine and Clinical Epidemiology, the UNC project on Supporting Appropriate Implementation of Lung cancer Screening (SAILS) is bringing together institutional experts as well as patient stakeholders to find ways to realize the benefits while minimizing the harms of the newly recommended screening test for lung cancer.
UNC Lineberger Comprehensive Cancer Center researchers and eight other leading cancer research institutions have won a five-year, $12 million grant to try to find treatments for a group of cancers linked to mutations in the NF1 gene.
Researchers from Norway visited the cancer center last week to learn firsthand about UNCseq, a clinical trial launched in 2011 at the N.C. Cancer Hospital. In the trial, researchers use a profile of the genetic and molecular alterations in patients' tumors to try to identify targeted treatments for them.
An $11.3 million, five-year grant from the National Cancer Institute will fund four studies by researchers with the Carolina Center of Cancer Nanotechnology Excellence.
A UNC Lineberger-led study, published today in Nature Genetics, paves the way for potential personalized medicine approaches for the deadly cancer type.
Fourteen-year-old star baseball player Liam Canard, of Raleigh, has been playing baseball throughout his battle with Hodgkin's lymphoma. Yesterday, thanks to Make-A-Wish of Eastern North Carolina, Liam received a gift that will help him hone his hitting while also taking his mind off his journey with cancer, and local media was there to cover it. View and read our wrap-up of media coverage, which includes Liam, his family, and pediatric hematologist-oncologist Dr. Patrick Thompson.
The editors of the MIT Technology Review highlighted Gu’s work on a novel way to monitor and treat diabetes.
In an article published in JAMA Oncology today, a study led by UNC Lineberger's Ethan Basch and colleagues shows that a system they developed accurately and reliably captures the patient experience with cancer drug side effects.
James Bear, PhD, uncovers the intricate mechanisms that allow certain cells to move, discoveries with implications for cancer metastasis.