60-year-old Maxine Pender of Edgecombe County receives healthy stem cells from her older brother for a bone marrow transplant, the tried and true treatment for her type of leukemia.
This center and its facility enables advanced research in cancer, neuroscience, medical imaging, computer science, drug discovery, nanotechnology, and imaging instrumentation.
Dr. Anders was chosen for her work on the identification of the prognosis and treatment of breast cancer brain metastases. Dr. Hoadley is being recognized for her contributions to a UNC-led analysis of glioblastomas (fast-growing malignant brain tumors).
It's a gene called DOT1L, and if you don’t have enough of the DOT1L enzyme, you could be at risk for some types of heart disease. These findings by UNC researchers appear in the journal Genes and Development.
The projects focus on areas of the state where cancers, and in particular breast, lung and colorectal cancers, are common and place a burden on the health of North Carolinians.
Serious illness most often brings devastating hardship, but it also has the potential to bring blessings with positive impact. Two couples from eastern North Carolina are living proof of how serious illness binds strangers in life-enriching ways.
A team of researchers led by Blossom Damania, PhD, has shown for the first time that the Kaposi sarcoma virus has a decoy protein that impedes a key molecule involved in the human immune response.
A new study shows that a test of biomarkers for DNA methylation is technically feasible and could aid in earlier, more precise diagnosis of melanoma.
The program will feature talks by physician/scientists and a patient’s parents on topics ranging from indoor tanning to clinical trials and from genetic testing to psychosocial support for melanoma patients.
The enzyme, known as Rad18, detects a protein called DNA polymerase eta (Pol eta) and accompanies it to the sites of sunlight-induced DNA damage, enabling accurate repair. When Pol eta is not present, alternative error-prone polymerases take its place – a process that leads to DNA mutations often found in cancer cells.
A team of researchers led by Channing Der, PhD, has made a discovery about how the Ras oncogene chooses a signaling pathway and how the consequences of that choice play out in cellular development.
Calling all runners! Sign up for the 2011 Wachovia Tar Heel 10-miler that will be held this year on April 9. The event is expected to sell out – come out and run the 10-miler, the Fleet Feet 4-miler, volunteer for the race, or cheer on the participants as they run through some of the most scenic routes in Chapel Hill.
Researchers investigating a genetic mutation in brain cancer and leukemia patients have discovered how one cancer metabolite battles another normal metabolite to contribute cancer development.
Calling all runners! Sign up for the 2011 Wachovia Tar Heel 10-miler that will be held this year on April 9. The event is expected to sell out – come out and run 10-miler, the Fleet Feet 4-miler, volunteer for the race or cheer on the participants as they run through some of the most scenic routes in Chapel Hill.
Sullivan among six faculty elected fellows of the American Association for the Advancement of Science
Patrick F. Sullivan, MD, Ray M. Hayworth and Family Distinguished Professor of Psychiatry and professor of genetics in the UNC School of Medicine, is among six UNC faculty members who have been named fellows of the American Association for the Advancement of Science.
The results show that basal-like breast cancer is equally aggressive in African American and white women, and that African American women had worse outcomes no matter what kind of breast cancer they developed.
A new paper by Aziz Sancar, MD, PhD and his colleagues takes an important step in understanding the underlying molecular signals that influence a broad array of biological processes ranging from the sleep-wake cycle to cancer growth and development.
This is the first-ever integrated analysis of the molecular processes that control genome function in an animal, which has the potential to speed understanding of the molecular processes in human cells.
Recent research from the University of North Carolina at Chapel Hill has found a number of issues with histone antibodies, the main tools used to decipher this code, suggesting they may need more rigorous testing.
In a paper published in Nature Structural and Molecular Biology, UNC's Jason Lieb and colleagues from across the country describe how they tested more than 200 antibodies against 57 histone modifications (or flavors) in three different organisms, using three different tests commonly used in this kind of genetic analysis.