Cancer

The latest cancer news from UNC Health Care and the UNC School of Medicine.

Chaperone enzyme provides new target for cancer treatments

The enzyme, known as Rad18, detects a protein called DNA polymerase eta (Pol eta) and accompanies it to the sites of sunlight-induced DNA damage, enabling accurate repair. When Pol eta is not present, alternative error-prone polymerases take its place – a process that leads to DNA mutations often found in cancer cells.

Chaperone enzyme provides new target for cancer treatments - Read More…

Roundworm unlocks pancreatic cancer pathway

Roundworm unlocks pancreatic cancer pathway

A team of researchers led by Channing Der, PhD, has made a discovery about how the Ras oncogene chooses a signaling pathway and how the consequences of that choice play out in cellular development.

Roundworm unlocks pancreatic cancer pathway - Read More…

2011 Wachovia Tar Heel 10-miler to benefit UNC Lineberger, UNC Cancer Care

2011 Wachovia Tar Heel 10-miler to benefit UNC Lineberger, UNC Cancer Care

Calling all runners! Sign up for the 2011 Wachovia Tar Heel 10-miler that will be held this year on April 9. The event is expected to sell out – come out and run the 10-miler, the Fleet Feet 4-miler, volunteer for the race, or cheer on the participants as they run through some of the most scenic routes in Chapel Hill.

2011 Wachovia Tar Heel 10-miler to benefit UNC Lineberger, UNC Cancer Care - Read More…

Molecular battle in cancer cells offers clues for treatment

Molecular battle in cancer cells offers clues for treatment

Researchers investigating a genetic mutation in brain cancer and leukemia patients have discovered how one cancer metabolite battles another normal metabolite to contribute cancer development.

Molecular battle in cancer cells offers clues for treatment - Read More…

2011 Wachovia Tar Heel 10-miler to benefit UNC Lineberger, UNC Cancer Care

2011 Wachovia Tar Heel 10-miler to benefit UNC Lineberger, UNC Cancer Care

Calling all runners! Sign up for the 2011 Wachovia Tar Heel 10-miler that will be held this year on April 9. The event is expected to sell out – come out and run 10-miler, the Fleet Feet 4-miler, volunteer for the race or cheer on the participants as they run through some of the most scenic routes in Chapel Hill.

2011 Wachovia Tar Heel 10-miler to benefit UNC Lineberger, UNC Cancer Care - Read More…

Sullivan among six faculty elected fellows of the American Association for the Advancement of Science

Sullivan among six faculty elected fellows of the American Association for the Advancement of Science

Patrick F. Sullivan, MD, Ray M. Hayworth and Family Distinguished Professor of Psychiatry and professor of genetics in the UNC School of Medicine, is among six UNC faculty members who have been named fellows of the American Association for the Advancement of Science.

Sullivan among six faculty elected fellows of the American Association for the Advancement of Science - Read More…

UNC study provides further insight into racial disparities in breast cancer

The results show that basal-like breast cancer is equally aggressive in African American and white women, and that African American women had worse outcomes no matter what kind of breast cancer they developed.

UNC study provides further insight into racial disparities in breast cancer - Read More…

UNC scientists pinpoint link between light signal and circadian rhythms

UNC scientists pinpoint link between light signal and circadian rhythms

A new paper by Aziz Sancar, MD, PhD and his colleagues takes an important step in understanding the underlying molecular signals that influence a broad array of biological processes ranging from the sleep-wake cycle to cancer growth and development.

UNC scientists pinpoint link between light signal and circadian rhythms - Read More…

International team including UNC scientist probes DNA function

International team including UNC scientist probes DNA function

This is the first-ever integrated analysis of the molecular processes that control genome function in an animal, which has the potential to speed understanding of the molecular processes in human cells.

International team including UNC scientist probes DNA function - Read More…

Tools used to decipher 'histone code' may be faulty

Tools used to decipher 'histone code' may be faulty

Recent research from the University of North Carolina at Chapel Hill has found a number of issues with histone antibodies, the main tools used to decipher this code, suggesting they may need more rigorous testing.

Tools used to decipher 'histone code' may be faulty - Read More…

UNC-led team tests commonly-used antibodies

UNC-led team tests commonly-used antibodies

In a paper published in Nature Structural and Molecular Biology, UNC's Jason Lieb and colleagues from across the country describe how they tested more than 200 antibodies against 57 histone modifications (or flavors) in three different organisms, using three different tests commonly used in this kind of genetic analysis.

UNC-led team tests commonly-used antibodies - Read More…

Raj Pruthi named chief of urologic surgery in UNC School of Medicine

Raj Pruthi named chief of urologic surgery in UNC School of Medicine

In addition to his new role as division chief, Pruthi is an associate professor of surgery and director of urologic oncology. He also serves as disease group leader for the Genitourinary Oncology program at the UNC Lineberger Comprehensive Cancer Center.

Raj Pruthi named chief of urologic surgery in UNC School of Medicine - Read More…

UNC team discovers mechanistic link between genetic variation and risk of atherosclerotic disease

UNC team discovers mechanistic link between genetic variation and risk of atherosclerotic disease

Previous genome-wide association studies (GWAS) have shown that common genetic variants located near these genes are associated with diseases of aging such as cancer, heart attack, stroke, type 2 diabetes and frailty. Yet how these variants contribute to the risk of these ailments was not known.

UNC team discovers mechanistic link between genetic variation and risk of atherosclerotic disease - Read More…

HSL Hosts Book Drive for Pediatric Cancer Patients

HSL Hosts Book Drive for Pediatric Cancer Patients

The Health Sciences Library, along with several other UNC departments and organizations, is once again sponsoring a book drive on behalf of the Book Fairy, an organization that donates children's books to the Pediatric Oncology Clinic at UNC Hospitals. Please donate by Dec. 8!

HSL Hosts Book Drive for Pediatric Cancer Patients - Read More…

HSL Hosts Book Drive for Pediatric Cancer Patients

HSL Hosts Book Drive for Pediatric Cancer Patients

From Nov. 8 through Dec. 9, 2010, the Health Sciences Library, along with several other UNC departments and organizations, is once again sponsoring a book drive on behalf of the Book Fairy, an organization that donates children's books to the Pediatric Oncology Clinic at UNC Hospitals.

HSL Hosts Book Drive for Pediatric Cancer Patients - Read More…

2010 Oncology Nursing and Service Awards Presented

2010 Oncology Nursing and Service Awards Presented

Ann Fletcher, Sam Sharf and Liz Sherwood each received a 2010 Oncology Nursing Excellence Award. Dan Roscicki was recognized with a Clinical Services Excellence Award.

2010 Oncology Nursing and Service Awards Presented - Read More…

UNC scientists identify cellular communicators for cancer virus

A new discovery by UNC scientists describes how cells infected by the Epstein-Barr virus (EBV) produce small vesicles or sacs called exosomes, changing their cellular “cargo” of proteins and RNA.

UNC scientists identify cellular communicators for cancer virus - Read More…

UNC team discovers promising target for new pancreatic cancer treatments

UNC team discovers promising target for new pancreatic cancer treatments

In a paper published in the Journal of Biological Chemistry, a team from UNC Lineberger Comprehensive Cancer Center has narrowed the focus of this scientific quest to a protein called RGL2.

UNC team discovers promising target for new pancreatic cancer treatments - Read More…

UNC startup receives federal grant to kick-start cancer research commercialization

UNC startup receives federal grant to kick-start cancer research commercialization

The company, G-Zero Therapeutics, is commercializing a high potential marker of molecular age measured from a patient blood sample, which could assist physicians in making more informed treatment-management decisions.

UNC startup receives federal grant to kick-start cancer research commercialization - Read More…

UNC scientists receive National Cancer Institute grant to address cancer health disparities

UNC scientists receive National Cancer Institute grant to address cancer health disparities

The five-year, $3.9 million grant will be used to target 13 North Carolina counties through the Carolina Community Network to Reduce Cancer Health Disparities.

UNC scientists receive National Cancer Institute grant to address cancer health disparities - Read More…

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