In a first-of-its-kind-study, researchers at the University of North Carolina Lineberger Comprehensive Cancer Center discovered and applied a new screening technique capable of testing thousands of potential drug compounds to see if those compounds can reverse abnormal DNA unwinding in Ewing sarcoma, a bone and soft tissue cancer that’s most common in teens and young adults.
The joint UNC/NC State researcher also earned a grant from JDRF and Sanofi to further develop glucose responsive insulin therapies for diabetes.
As part of the “Cancer Moonshot” federal initiative to spur breakthroughs in cancer research, Biden hosted a roundtable discussion on Feb. 10 at the Duke University School of Medicine that featured cancer experts and leaders from UNC. Among the experts chosen for the panel were Stephanie Wheeler, PhD, UNC Lineberger member and assistant professor of health policy and management at the UNC Gillings School of Global Public Health, and Niklaus Steiner, UNC professor and co-founder of the Chapel Hill-based Be Loud! Sophie Foundation, which supports adolescents and young adults with cancer.
A UNC Lineberger researcher was first-author of a report published in the Journal of Clinical Oncology that details guidelines for the active surveillance of men with low-risk prostate cancer. The guidelines, originally authored by Cancer Care Ontario, were reviewed and endorsed by the American Society of Clinical Oncology with some revisions.
UNC Lineberger joins nation’s cancer centers in endorsement of HPV vaccination for cancer prevention
Joint statement urges parents, young adults and physicians to act to increase vaccination rates
In a study published in the journal Annals of Surgery, researchers report that breast cancer patients surveyed about their knowledge of breast reconstruction were only moderately informed about the procedure, and their knowledge of complications was low.
In the journal Cell Reports, UNC Lineberger researchers report that when they removed Dicer from preclinical models of medulloblastoma, a common type of brain cancer in children, they found high levels of DNA damage in the cancer cells, leading to the cells’ death.
An Internet-based system for symptom collection benefited patients while giving them a clearer voice in their own care.
The new cancer drug delivery system improved efficacy of standard chemotherapy for ovarian cancer in mice with limited toxicity.
Findings suggest that radiologists studying mammograms observed suspicious markers that could have been indications of future cancer development.
The award, made possible through a donation from Lenovo chairman and CEO Yuanqing Yang, recognizes the research achievements of young tenured faculty.
UNC Lineberger-led study finds higher vitamin D and calcium intake does not reduce colorectal polyp risk
A UNC Lineberger-led study published in the New England Journal of Medicine found that vitamin D and calcium supplements do not reduce the risk of colorectal adenomas, which are benign tumors that can evolve into colorectal cancer.
From aspiring soccer star to world-renowned biochemist, Aziz Sancar, MD, PhD, joined Carolina’s other Nobel Laureate, Oliver Smithies, PhD, during a celebration of science at the UNC School of Medicine.
In the recent U.S. News and World Report rankings of America’s Best Hospitals, UNC Hospitals was nationally ranked in five of the 16 specialties. In this series, we profile these specialties to learn more about what makes them so outstanding.
Sancar’s team mapped DNA repair mechanisms that protect us against cancer.
The new drug-creation method could allow cancer drugs to last longer in the body to attack tumors, as well as cancer cells floating in the blood stream.
A science class captured Catherine Fahey’s imagination. A mother’s battle with cancer led her to pursue medicine as a career. At UNC, Fahey found a home at the junction of research and patient care.
When it comes to meeting the challenge of implementing new lung cancer screening guidelines, UNC is taking a multidisciplinary approach. Led by Daniel S. Reuland, MD MPH, Division of General Internal Medicine and Clinical Epidemiology, the UNC project on Supporting Appropriate Implementation of Lung cancer Screening (SAILS) is bringing together institutional experts as well as patient stakeholders to find ways to realize the benefits while minimizing the harms of the newly recommended screening test for lung cancer.
UNC Lineberger Comprehensive Cancer Center researchers and eight other leading cancer research institutions have won a five-year, $12 million grant to try to find treatments for a group of cancers linked to mutations in the NF1 gene.
Researchers from Norway visited the cancer center last week to learn firsthand about UNCseq, a clinical trial launched in 2011 at the N.C. Cancer Hospital. In the trial, researchers use a profile of the genetic and molecular alterations in patients' tumors to try to identify targeted treatments for them.