Diabetes

The latest diabetes and endocrinology news from UNC Health Care and the UNC School of Medicine.

Buse leads clinical trial of new diabetes treatment

Buse leads clinical trial of new diabetes treatment

The study is designed to evaluate whether TTP399 is well tolerated when administered as an add-on to insulin therapy and can improve daily glucose profiles and HbA1c in people living with type 1 diabetes.

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Smart Artificial Beta Cells Could Lead to New Diabetes Treatment

Smart Artificial Beta Cells Could Lead to New Diabetes Treatment

In lab experiments and animal models, UNC and NC State researchers led by Zhen Gu, PhD, designed synthetic beta cells to secrete insulin in response to high blood sugar.

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UNC/NC State spinout company raises $5.8M for ‘smart’ insulin devices

UNC/NC State spinout company raises $5.8M for ‘smart’ insulin devices

A Research Triangle Park startup founded by Zhen Gu, PhD, a biomedical engineer with joint faculty appointments at UNC and NC State University received a $5.8 million cash infusion to continue translation efforts of ‘smart’ insulin devices.

UNC/NC State spinout company raises $5.8M for ‘smart’ insulin devices - Read More…

UNC co-leads large clinical trial on new combo therapy for type 2 diabetes

UNC co-leads large clinical trial on new combo therapy for type 2 diabetes

New insulin degludec has comparable cardiovascular safety rates to insulin glargine U100 but with less risk of triggering low blood sugar.

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Is the finger-stick blood test necessary for type 2 diabetes treatment?

Is the finger-stick blood test necessary for type 2 diabetes treatment?

In the first large pragmatic trial of its kind in the United States, results from a UNC School of Medicine study show that checking finger-stick blood sugars may not help diabetes patients who do not use insulin.

Is the finger-stick blood test necessary for type 2 diabetes treatment? - Read More…

Researchers implicate suspect in heart disease linked to diabetes

Researchers implicate suspect in heart disease linked to diabetes

In their study of the IRS-1 protein, researchers at the University of North Carolina found a new lead for reversing or preventing heart disease associated with diabetes.

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UNC clinical trials play crucial role in FDA approval for diabetes drug

UNC clinical trials play crucial role in FDA approval for diabetes drug

Led by John Buse, MD, PhD, director of the UNC Diabetes Care Center, the clinical research of UNC doctors and the participation of thousands of patients culminates in a new, effective, and safe daily injectable drug to combat type-2 diabetes.

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Diabetes drug lowers risk of cardiovascular complications, kidney disease

Diabetes drug lowers risk of cardiovascular complications, kidney disease

For the first time, a large clinical trial showed across-the-board cardiovascular benefit of a diabetes drug – liraglutide – a much-needed outcome for people with type 2 diabetes.

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UNC diabetes expert John Buse featured twice on WRAL

UNC diabetes expert John Buse featured twice on WRAL

Buse led a global clinical trial on the new type-2 diabetes drug iDegLira, and he spoke to the local news station about the best ways to screen for the disease.

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Scientists create painless patch of insulin-producing beta cells to control diabetes

Scientists create painless patch of insulin-producing beta cells to control diabetes

The new “smart cell patch” developed at UNC and NC State is a proof of principle to treat millions of people with type-1 and advanced type-2 diabetes.

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New type-2 diabetes therapy proves better than traditional insulin injections

New type-2 diabetes therapy proves better than traditional insulin injections

UNC-led global phase-3 clinical trial sets the stage for improved management of a disease that affects nearly 30 million Americans.

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Biomedical engineer Zhen Gu receives prestigious Sloan Fellowship

Biomedical engineer Zhen Gu receives prestigious Sloan Fellowship

The joint UNC/NC State researcher also earned a grant from JDRF and Sanofi to further develop glucose responsive insulin therapies for diabetes.

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Biomedical engineer Zhen Gu, PhD, tabbed as top young innovator

Biomedical engineer Zhen Gu, PhD, tabbed as top young innovator

The editors of the MIT Technology Review highlighted Gu’s work on a novel way to monitor and treat diabetes.

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Diabetes drug metformin’s primary effect is in the gut, not the bloodstream

Diabetes drug metformin’s primary effect is in the gut, not the bloodstream

New study in Diabetes Care suggests new delayed-release metformin could help 40 percent of type 2 diabetes patients that currently can’t take metformin.

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UNC researchers find two biomarkers linked to severe heart disease

UNC researchers find two biomarkers linked to severe heart disease

The finding published in PLoS One suggests that elevated oxidized LDL cholesterol and fructosamine – a measure of glycated proteins in blood sugar – are signposts for the development of severe coronary disease, especially in females.

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Smart insulin patch could replace painful injections for diabetes

Smart insulin patch could replace painful injections for diabetes

A joint effort between diabetes doctors and biomedical engineers could revolutionize how people with diabetes keep their blood sugar levels in check.

Smart insulin patch could replace painful injections for diabetes - Read More…

UNC diabetes researcher featured on WRAL

UNC diabetes researcher featured on WRAL

TV segment focused diabetes prevention and screening and featured John Buse, MD, PhD, chief, Division of Endocrinology, executive associate dean for clinical research.

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Diabetes researcher earns ADA grant to design nanoparticles to control blood sugar

Diabetes researcher earns ADA grant to design nanoparticles to control blood sugar

The research by Zhen Gu, PhD, assistant professor in the UNC-NCSU joint department of biomedical engineering, aims to improve methods for delivering precise amounts of medications less frequently.

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Diabetes researchers urge for new screening and management approach

Diabetes researchers urge for new screening and management approach

By treating people earlier, doctors could help diabetes patients avoid the most severe, life-threatening complications that stem from prolonged periods of elevated blood glucose.

Diabetes researchers urge for new screening and management approach - Read More…

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