UNC-led team awarded $2 million supplemental grant to support AIDS cure research

The Collaboratory of AIDS Researchers for Eradication, or CARE, a multi-institutional research team led by David Margolis, MD, professor of medicine at the UNC School of Medicine, has been awarded a $2 million supplemental grant from the National Institutes of Health to conduct expanded analysis of resting CD4+ T-cells of people infected with HIV.

CD4+ T-cells are special cells that the virus uses to replicate.

With the new funding, Margolis and others in the collaboratory will study the effect of a variety of interventions on these resting CD4+ T-cells.

CARE researchers are studying latent, or “hidden,” HIV infection in patients who are controlling the virus with anti-AIDS drugs. Flushing out and clearing this hidden virus is critical to finding a cure for AIDS.

In July 2012, Margolis and other researchers at UNC published novel research showing that a drug used to treat certain types of lymphoma was able to dislodge hidden virus in patients receiving treatment for HIV.

This latest NIH funding supplements a previous $32 million, five-year award to CARE to develop strategies to cure AIDS.

CARE is a group of over 20 research scientists who believe that HIV can be eradicated by working together as a collaboratory, combining our scientific expertise, our efforts and our shared vision of a world free from HIV.  For more information and to get involved go to http://www.delaneycare.org/.

This story was originally published here.

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