Cardiac Resuscitation Technique Gaining Interest

James Manning, MD, director, Department of Emergency Medicine Resuscitation Research Laboratories, first began tinkering with a new technique for treating cardiac arrest in 1989. Now, more than 25 years later, the idea that many described as far-fetched at the time has drawn international attention, taking Manning to three continents to deliver lectures.

Cardiac Resuscitation Technique Gaining Interest click to enlarge James Manning, MD

The Selective Aortic Arch Profusion (SAAP), which Manning developed in his lab at UNC, is a method for treating cardiac arrests that are caused by traumatic hemorrhage or non-traumatic medical causes, such as acute sudden death. It works by inserting an aortic balloon catheter from a femoral artery to the thoracic aorta to allow for resuscitative perfusion of the heart and brain during cardiac arrest.

“When I first started working on this, a lot of people called it far-fetched, but in the last 10 years or so, advances in endovascular surgery have led people to looking at it with fresh eyes,” Manning said.

He said he has been working on this as a passion project over the years piecing together small grants to conduct small scale experiments in his lab.

“You tend to hang on to something when it’s your own invention,” Manning said.

He says his lab work has made him confident of the techniques effectiveness. He is now working to draw more attention in the hopes of one day beginning clinical trials. To that end, Manning is working in partnership with the U.S. Air Force 59th Wing Clinical Research Division on a two-year, $1.24 million research project aimed at advancing the clinical usage of the SAAP technique.

He has also been busy spreading the word through lectures and conferences.

“If you had told me even a few years ago that I’d have given 22 lectures across three continents, I would have told you that was crazy,” Manning said. “I’ve been working on this for so long, and now to see these results, it has really been mind boggling.”

Filed under: