2015 Call for Tobacco Center of Regulatory Science Pilot Project Proposals

The UNC SOM Center for Tobacco Regulatory Science and Lung Health P50 is funding pilot projects (up to $40,000 in direct costs). The purpose of the pilot projects is to fund new initiatives and to allow new investigators to pursue tobacco regulation research related to the effects of new and emerging tobacco products (e.g., little cigars, hookah, e-cigs, etc.) on innate defense. Pilot projects should seek to characterize the health effects of new and emerging tobacco products in an effort to inform the FDA’s tobacco regulatory practices. Please note that by law, the FDA can only fund studies that directly pertain to tobacco regulatory science, and they cannot fund research that will not inform or advise a future tobacco policy.

Investigators should meet one of the following criteria:

  1. Junior faculty at UNC-CH not currently funded by NIH grants and in need of funds to help prepare for R01-type applications.
  2. Established UNC-CH investigators not currently funded for work related to the Center’s focus but who wish to apply their areas of expertise to tobacco regulatory science.
  3. Funded investigators from the Center who wish to pursue a project that is different from their current focus, especially if the new project is in response to changes in the tobacco market.

Important Dates

Friday, August 14, 2015: Deadline for submission of Letter of Intent emailed to Flori Sassano (msassano@unc.edu) by 5:00pm. The one-page Letter of Intent must include the following:

  1. Name and Academic position
  2. Title of the pilot project
  3. Future scientific plans regarding new and emerging tobacco products (i.e., “Research Outline”)
  4. Statement regarding the applicability of the proposed pilot project to the UNC Center for Tobacco Regulatory Science and Lung Health

Friday, August 21, 2015: Invitation to submit a full application.

Friday, September 4, 2015: Deadline for submission of full application emailed to Flori Sassano at msassano@unc.edu by 5:00 p.m. The forms necessary for the full application are available here. Applications should not exceed the page limits and format below:

  1. Form Page 1: Face Page (Q2. Number, n/a; Q2. Title, UNC School of Medicine TCORS Pilot Project Program; Date of proposed period of supports, 09/01/2014 through 08/31/2015; Q11-Q13 do not need to be completed)
  2. Form Page 2: Summary, Relevance, Project/Performance Sites, Senior/Key Personnel, Other Significant Contributors, and Human Embryonic Stem Cells (Project Summary and Relevance sections should not exceed the box provided; Relevance refers to how the pilot project will contribute to the overall theme of the UNC Center for Tobacco Regulatory Science and Lung Health/Innate Defense)
  3. Continuation Format Page (Research strategy including background, specific aims, and any preliminary data; 3-5 pages not including references)
  4. Form Page 4:  Detailed Budget for Initial Budget Period (PI salary not allowed, salary may only be requested for project support personnel, e.g. research technician; funding for travel not allowed)
  5. Biographical Sketch Format Page (provide one for each key personnel, see Biographical Sketch Sample)

Friday, September 18, 2015: Provisional notice of awards. (N.B., all awards must be approved by the NIH/FDA before funds can be released.  Awards must be aligned with the mission of the FDA’s Center for Tobacco Products (Click here for more details).

Previously funded Projects:

5 Pilot & Feasibility Projects were funded in year 2.  These included 3 P&F projects from UNC faculty for ~$40,000 each.  The Faculty awards were as follows:

  • The Impact of Cigarette Smoke on Intestinal Microbiota and Intestinal Epithelium Homeostasis.   P Kay Lund
  • Assessing Airway Responses to e-Cigarette Exposure. Charles Esther
  • The Effect of New and Emerging Tobacco Products on Prothrombotic Biomarkers. Alisa Wohlberg
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