Friedreich's Ataxia Research Alliance General Research Grant

Friedreich's Ataxia Research Alliance FARA accepts LOIs from qualified investigators for projects that target FARA’s research priorities twice per year (due February 1 and July 15). The applicant may request a budget of up to $150,000 per year for one or two years.

The UNC Office of Corporate and Foundation Relations has identified the following private funding opportunities:

Friedreich's Ataxia Research Alliance (FARA)

http://www.curefa.org/types-of-grants.html

http://www.curefa.org/grant.html

http://www.curefa.org/RPMP/public/pgrpmphome.aspx

General Research Grant 

FARA accepts LOIs from qualified investigators for projects that target FARA’s research priorities twice per year (due February 1 and July 15). For those invited to submit a full application, the deadlines for submission are April 1 and September 15, respectively. On the Main Grant Page, put “General Research” in the “Grant Type” field. The applicant may request a budget of up to $150,000 per year for one or two years.  

ARA’s Grant Program Priorities

  • Advance understanding of neuroscience / neuro systems – understanding the neurodegeneration of FA and implications for therapies
  • Advance drug discovery
    • Highest priority in this category will be given to genetic, epigenetic and protein approaches that target increasing frataxin levels
  • Facilitate the drug development process and translational research so that the most promising discoveries are rapidly brought to treatment trials
    • Highest priority in this category will be given to IND-enabling studies, biomarker discovery and validation, early phase or pilot clinical studies
  • Advance clinical research – natural history, discovery and validation of clinical outcome measures and/or biomarkers, identification of early (including pre-symptomatic) quantifiable clinical features, patient reported outcomes, investigator-initiated clinical trials, or evidence-based clinical treatment guidelines
  • Reduce the morbidity and mortality caused by cardiac disease in FA 
Grant Types, Deadlines and Budget Limits

Grant Type

LOI Deadlines

Application Deadlines

Maximum Budget
(in US dollars)

General Research Grant

Feb 1
July 15

April 1
Sept 15

$150,000
per year
for 1 or 2 years

Keith Michael Andrus Cardiac Research Award

January 15

March 1

$150,000
per year
for 1 or 2 years

Kyle Bryant Translational Research Award

May 15

July 15

$250,000
per year
for 1 or 2 years

Bronya J. Keats International Research Collaboration Award

May 15

July 15

$200,000
per year
for 1 or 2 years

General Research Grant Subtype:

Postdoctoral Trainees and Ph.D. Students 

Salaries for all those contributing to the research project (PI, postdocs, graduate students, research associates, etc.) can be requested under personnel costs in the budget of a General Research Grant application. 

Additionally, FARA has an application subtype specifically for PIs requesting only salary (plus applicable benefits) to support postdoctoral trainees and Ph.D. students in their laboratory. The PI is encouraged to involve the trainee/student in the preparation of the research plan to be submitted with the application. The name and CV of the postdoctoral trainee or Ph.D. student must be included in the application. 

The guidelines for General Research Grants should be followed, but the only allowable budget item is salary for the postdoctoral trainee or Ph.D. student (plus applicable benefits and tuition support) and the requested amount must not exceed the appropriate NIH stipend level. 

Bronya J. Keats Award for International Collaboration in Research on FA 

FARA accepts LOIs focusing on FA research that relies on international collaboration among investigators in at least two different countries. Special consideration will be given to proposals that bring new scientists to the FA community. The rationale for the collaboration needs to be convincing and must clearly demonstrate that the research goals could not be achieved by just one of the participating groups and that the synergy among the groups is essential for the success of the project. 

The deadline for the LOI is May 15. For those invited to submit a full application, the deadline for submission is July 15. 

On the Main Grant Page, put “Keats Award” in the “Grant Type” field. The applicants may request a combined budget of up to $200,000 per year for one or two years. 

Phillip Bennett and Kyle Bryant Translational Research Award 

FARA accepts LOIs focusing on pre-clinical and clinical investigations that will advance treatments for FA. The specific aims must target one or more of the following:

  • Identification of biomarkers for FA that will elucidate disease variability, severity, and prognosis; facilitate drug screening, and/or optimize selection of patients and clinical endpoints for clinical trials;
  • Development of tools and technologies that can (a) be directly used for therapy development; (b) overcome existing obstacles to treatment and (c) be directly applied to, or adapted for, delivery of potential therapeutics;
  • Pre-clinical development and testing of potential therapeutics, biologics, and devices in cells and animals;
  • Clinical studies of patient outcome measures, potential interventions, or devices.

The deadline for the LOI is May 15. For those invited to submit a full application, the deadline for submission is July 15. On the Main Grant Page, put “PB and KB Translational Award” in the “Grant Type” field. The applicant may request a budget of up to $250,000 per year for one or two years. 

FARA will fund direct costs only. Individuals or organizations with a specific interest in organizing a scientific meeting should contact FARA’s Executive Director directly (jen.farmer@curefa.org). An executive summary outlining the goals and objectives of the meeting, intended participants, explanation of relevance to the FARA mission, timeline and budget will be required. All requests will be reviewed by FARA’s scientific review committee and a recommendation will be submitted to FARA’s Board of Directors. The final funding decision will be made by the Board. 

FARA’s Grant Program General Policies

  • A Letter of Intent (LOI) is required for all grant applications. This letter must contain a brief description of the objectives, rationale, and key preliminary data for the project, an estimate of the budget, and the CV/biosketch for the principal investigator (including contact information). It will be reviewed by the FARA Scientific Research Committee and, based on the outcome of this review, the applicant will be either invited to submit a full application or informed that the LOI is declined. This decision will usually be made within two weeks of receipt of the LOI.

LOIs are accepted from for-profit organizations, non-profit organizations, public or private institutions, and foreign institutions. The LOI must be submitted as a PDF file via email tojen.farmer@curefa.org. In the subject line indicate that this is an LOI and the type of grant you are applying for, eg. LOI General Research Grant.

  • LOIs and invited grant applications must meet the specified deadlines. Exceptions are made only for projects of high priority to FARA. With compelling justification for special consideration, investigators with high-priority projects may submit LOIs throughout the year and may also have a budget greater than $150,000 per year. Please submit all special consideration requests and LOIs to Jennifer Farmer via email, jen.farmer@curefa.org.
  • Occasionally FARA may issue Requests For Proposals (RFPs) targeting a high priority research area. Each RFP will have its own specific deadline and budget limit.
  • FARA funds only direct costs. Indirect costs will not be awarded.
  • Grant awards are made in one-year allocations. As stipulated in the contractual agreement with FARA, satisfactory progress reports (following the instructions under Reporting Requirements) must be received before FARA will provide funds for the second year of a 2-year project.
  • All unused funds at the end each year must be returned to FARA. In exceptional circumstances, FARA may approve a Request for a No-Cost Extension.
  • FARA reserves the right to terminate any grant award for inadequate progress, failure to submit reports, deviation in scope of the original research, and/or changes in FARA funding priorities. If an award is terminated, all unused funds must be returned to FARA.

The UNC Office of Corporate and Foundation Relations is available to provide assistance in pursuing privately funded opportunities. Email cfr@unc.edu or phone 919.962.3423.

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