Liu Lab receives $2 million grant for heart research

Jiandong Liu, PhD, assistant professor of pathology, member of the UNC McAllister Heart Institute, and director of the Zebrafish Aquaculture Core facility, has received a $2-million research grant from the NIH for his project "Molecular regulation of ventricular chamber maturation."

Liu Lab receives $2 million grant for heart research click to enlarge Fluorescent protein-labeled zebrafish ventricle from Liu Lab

Jiandong Liu, PhD, Assistant Professor of Pathology, member of the McAllister Heart Institute, and director of the Zebrafish Aquaculture Core facility, has received a $2 million research grant from the NIH for his project "Molecular regulation of ventricular chamber maturation." This research aims to understand how ventricular heart defects can arise by examining the mechanical and biochemical interactions that occur during embryonic heart development in a zebrafish model. Zebrafish offer unique opportunities for research as 70% of human genes have functional homologs in zebrafish, and the embryos develop externally and are transparent, offering ready visualization of their development.

In September 2017, he received one year of funding from the NIH for a related project. The new funding demonstrates the NIH's continuing commitment to supporting Dr. Liu's research.