Doris Duke Charitable Foundation: Sickle Cell Disease/Advancing Cures

The Doris Duke Charitable Foundation (DDCF) is accepting applications to support research into cures for sickle cell disease. DDCF seeks to fund research needed to advance curative therapies (e.g., gene modification, bone marrow transplant) or new drug candidates that would decrease sickling of red blood cells (e.g., molecules that would increase fetal hemoglobin) and encourages crossover of researchers from other disciplines and specialties to work on sickle cell disease. Award amount up to $300,000 over three (3) years. The application deadline is May 31, 2019 by 3:00pm ET.

The UNC Chapel Hill Office of Corporate and Foundation Relations has identified the following private funding opportunity:

Doris Duke Charitable Foundation: Sickle Cell Disease/Advancing Cures
http://www.ddcf.org

Award Amount: up to $300,000 over three (3) years
Application Deadline: May 31, 2019 by 3:00pm ET
Anticipated Award Notification: August 2019
Anticipated Award Start Date: September 1, 2019
RFP Synopsis:

The Doris Duke Charitable Foundation (DDCF) is accepting applications to support research into cures for sickle cell disease. Research studies of interest include, but are not limited to:

  • Advance gene therapies into the clinic, including gene addition and genome editing
  • Build on globin regulatory mechanisms to restore red blood cell function
  • Advance bone marrow transplant approaches to minimize toxicities and improve outcomes

DDCF seeks to fund research needed to advance curative therapies (e.g., gene modification, bone marrow transplant) or new drug candidates that would decrease sickling of red blood cells (e.g., molecules that would increase fetal hemoglobin) and encourages crossover of researchers from other disciplines and specialties to work on sickle cell disease. Applicants must propose a clinical research project that meets the foundation’s definition: the scientific investigation of the etiology, prevention, diagnosis, or treatment of human disease using human subjects, human populations or materials of human origin. Included in the definition are studies that utilize tissues or pathogens only if they can be linked to a patient. Please note that DDCF does not support research with non-human animals. Eligible applicants must hold an advanced doctoral degree (PhD, MD, MD/PhD, DO or equivalent) and have a full-time faculty rank appointment (Instructor, Assistant Professor, Associate Professor, or Professor). Only one application per Principal Investigator is allowed; however, an investigator may be considered part of the key personnel of another application. Applications may be submitted by an individual principal investigator or by teams of up to two principal investigators who will be co-equals sharing the responsibility for leading and directing the research project. In the case of a team application, choose one of the principal investigators to submit the application; this person will be DDCF’s point of contact for the application and grant, if awarded. Awards are made to the institution, not the individual. Indirect costs may not exceed 10% of annual total direct cost, including equipment.

To read the full application guidelines, including detailed eligibility requirements, please visit: https://www.ddcf.org/what-we-fund/medical-research/goals-and-strategies/advance-biomedical-research-and-innovation/sickle-cell-disease-advancing-cures/?id=5081

If you have any questions about this funding opportunity, please contact Brooke Church, Senior Director of Corporate and Foundation Relations for Health Affairs, at Brooke_Church@unc.edu or (919) 962-0024. The UNC Chapel Hill Office of Corporate and Foundation Relations is available to assist UNC personnel pursuing privately funded opportunities.

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