Wendell Yarbrough, MD, MMHC, "HPV Associated Cancer Evolution of a Disease from Initial Description to Targeted Therapy"

HPV-associated head & neck squamous cell carcinoma (HPV+ HNSCC) was unrecognized until the late 1990s, but since that its incidence has dramatically increased in the United States making it the most frequently diagnosed cancer caused by HPV. Most knowledge about HPV carcinogenesis comes from study of uterine cervical cancer, but several differences between uterine cervical cancer and HPV+ HNSCC led us and others to identify molecular differences that support a new mechanism through which HPV causes human cancer.

When Sep 11, 2019
from 07:15 AM to 08:15 AM
Where 4008 Old Clinic Auditorium
Contact Name
Contact Phone 919-445-0369
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Dr. Wendell (Dell) Yarbrough is the Chairman of the Department of Otolaryngology/Head and Neck Surgery at the University of North Carolina.  He was a Morehead Scholar at the University of North Carolina before matriculating to the University of North Carolina School of Medicine and graduating in 1989 with honors and distinction. He then completed a Surgical Oncology Fellowship at the University of North Carolina at Chapel Hill School of Medicine under the auspices of Edison Liu before joining the faculty as an Assistant Professor in Otolaryngology/Head and Neck Surgery in 1996. Dr. Yarbrough moved to Vanderbilt in 2003 to become the Barry Baker Professor and co-leader of the Thoracic/Head and Neck Program in the Vanderbilt Ingram Cancer Center. In 2012, Dr. Yarbrough moved to Yale as Professor and Chief of Otolaryngology, Director of the Head and Neck Cancer Program and co-leader of the Virus and Other Infections-Associated Cancer (VOIC) Program in the Yale Cancer Center. In 2018, Dr. Yarbrough returned to the University of North Carolina at Chapel Hill School of Medicine as the Thomas J. Dark Distinguished Professor and Chairman of Otolaryngology/Head and Neck Surgery.

Dr. Yarbrough’s clinical practices focus on Head and Neck Cancers including those of the mouth, throat, voice box, neck, thyroid and salivary glands including minimally invasive approaches, (transoral robotic surgery (TORS) and transoral laser microsurgery (TLM).  Dr. Yarbrough has been active in translational research for more than 25 years with recent interests focusing on human papillomavirus (HPV)-associated head and neck cancer. 

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