A UNC Maternal-Fetal Medicine Network trial has shown that, among pregnant and postpartum individuals, SARS-CoV-2 infection was associated with increased risk of maternal mortality or serious morbidity from obstetric complications.
A UNC Maternal-Fetal Medicine Network (MFMU) trial currently underway has shown that SARS-CoV-2 infection was associated with an increased risk for a composite outcome of maternal mortality or serious morbidity from obstetric complications.
Among infected women, premature birth was more likely and cesarean delivery was more prevalent in those with severe symptoms. Women with a BMI ≥ 30 who identify as Black or Hispanic were more likely to develop complications.
Previously, the same trial concluded that compared with pregnant patients with SARS-CoV-2 infection without symptoms, those with severe–critical COVID-19, but not those with mild–moderate COVID-19, were at increased risk of perinatal complications. Those findings were reported here.
The UNC MFMU is part of a national network focusing on clinical questions regarding matters concerning maternal fetal medicine and obstetrics. They are funded by the Eunice Kennedy Shriver National Institutes of Child Health and Human Development (NICHD). John Thorp, MD, McAllister Distinguished Professor in the Department of Obstetrics and Gynecology, is the Principal Investigator for the UNC clinical center. The Nurse Coordinator is Kelly Clark, RN. Learn more about the MFMU.