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Scientists Identify Underlying Molecular Mechanisms of Alexander Disease
Researchers led by UNC School of Medicine’s Natasha Snider, PhD, used human induced pluripotent stem cells and CRISPR/Cas9 gene editing to make important basic science discoveries about the molecular underpinnings of Alexander disease, a rare neurodegenerative condition that is often fatal to young children.
Located in News / 2019 / November
Machine Learning Helps Scientists Measure Important Inflammation Process
Led by the UNC School of Medicine lab of Leslie Parise, PhD, researchers created an artificial intelligence tool to measure NETosis, an important inflammatory process by which certain white blood cells trap invaders like bacteria. This work will help scientists find ways to stop or promote the process in disease states.
Located in News / 2019 / December
UNC Health Care Introduces App to Help Patients Navigate Hospitals, Clinics and Parking
Smartphone technology from Gozio Health provides directions, doctor directories and more
Located in News / 2019 / December
Scientists Discover Key Neural Circuit Regulating Alcohol Consumption
The UNC School of Medicine lab of Zoe McElligott, PhD, found that alcohol consumption is regulated by the activity of a particular set of neurons in a specific brain region, a discovery that could lead to a better understanding of why some casual drinkers develop an alcohol use disorder.
Located in News / 2019 / December
Scientists Take a Big Step toward Building a Better Opioid
In a paper published in Cell, UNC School of Medicine researchers led by Bryan Roth, MD, PhD, show how to activate only one kind of brain receptor vital for pain relief. This receptor is not involved in addiction or respiratory depression that leads to death – the most severe side effects of opioid use.
Located in News / 2018 / January
Hormone therapy could effectively prevent depression for some women in the menopause transition
Research conducted by Susan Girdler, PhD, and David Rubinow, MD, and published in JAMA Psychiatry, is the first to conclude that a year of hormone therapy can effectively prevent the onset of depressive symptoms for women during the menopause transition.
Located in News / 2018 / January
Nash UNC Health Care Names L. Lee Isley as CEO
Isley has served as CEO for Granville Health System in Oxford, NC, since 2006, and has held a variety of roles in his 30-year health care career.
Located in News / 2018 / January
Narrowing the gap toward precision medicine for pancreatic cancer
To improve treatment and our understanding of one of the deadliest cancers in the United States, UNC Lineberger's Jen Jen Yeh, MD, was involved in two studies that take different approaches to precision medicine for pancreatic cancer.
Located in News / 2018 / January
Cystic Fibrosis Discovery: Bacterial Burden Begins During First Years of Life
UNC School of Medicine scientists show that therapies to break up mucus in toddlers might offer the best route to a longer life for CF patients.
Located in News / 2018 / January
Scientific Breakthrough Could Lead to Better Antipsychotic Drugs
Published in Nature, research from the lab of Bryan L. Roth, MD, PhD, revealed the first-ever crystal structure of the dopamine 2 receptor bound to an antipsychotic drug – a much-needed discovery in the quest to create effective drugs with fewer side effects to treat bipolar disorder, schizophrenia, and other conditions.
Located in News / 2018 / January