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UNC researchers engineer 'protein switch' to dissect role of cancer’s key players
In the first application of this approach, the UNC researchers showed how a protein called Src kinase influences the way cells extend and move, a previously unknown role that is consistent with the protein’s ties to tumor progression and metastasis.
Located in News / 2013 / April
UNC researchers find final pieces to the circadian clock puzzle
Sixteen years after scientists found the genes that control the circadian clock in all cells, the lab of UNC’s Aziz Sancar, MD, PhD, discovered the mechanisms responsible for keeping the clock in sync.
Located in News / 2014 / September
UNC researchers find promising new angle for drugs to prevent stroke and heart attack
A new study — the first to apply a new screening technique to human platelets — netted a potential drug target for preventing dangerous blood clots in high-risk people.
Located in News / 2013 / August
UNC researchers find two biomarkers linked to severe heart disease
The finding published in PLoS One suggests that elevated oxidized LDL cholesterol and fructosamine – a measure of glycated proteins in blood sugar – are signposts for the development of severe coronary disease, especially in females.
Located in News / 2015 / July
UNC researchers identify cellular distress signal
Researchers from the University of North Carolina School of Medicine have discovered that a well-known associate of G protein-coupled receptors -- a common target of FDA-approved drugs -- may play a critical role in mounting a rescue effort to avert an intracellular meltdown.
Located in News / 2013 / August
UNC researchers identify important step in sperm reprogramming
A study from the UNC School of Medicine has illuminated a key step of demethylation, giving stem cell researchers critical information as they try to reprogram adult cells to mimic the curative and self-renewing properties of stem cells.
Located in News / 2011 / September
UNC researchers identify seventh and eighth bases of DNA
For decades, scientists have known that DNA consists of four basic units -- adenine, guanine, thymine and cytosine. In recent history, scientists have expanded that list from four to six. Now researchers from the UNC School of Medicine have discovered the seventh and eighth bases of DNA.
Located in News / 2011 / July
UNC researchers link aging to cellular interactions that occur across generations
Shawn Ahmed, PhD, shows that tweaking specific cellular mechanisms helps tiny worms overcome infertility through a pathway of cellular interactions that result in long life. The finding gives clues to how the molecular interactions in cells of one organism affect progeny many generations later.
Located in News / 2014 / April
UNC researchers link gene to increased dendritic spines – a signpost of autism
By deleting the NrCAM gene, scientists have found a potential way to cut back on the neural connections implicated in Autism Spectrum Disorder.
Located in News / 2014 / September
UNC researchers pinpoint new role for enzyme in DNA repair, kidney cancer
The discovery, from the lab of Brian Strahl, PhD, offers insights for the creation of better, more targeted therapies for various forms of cancer.
Located in News / 2014 / June