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Post Heart Attack: How can scar tissue be turned back into healthy heart muscle?
For the first time, UNC scientists detail crucial differences in two leading methods for generating heart muscle cells, a key strategy for new post-heart attack therapies.
Located in Biochemistry and Biophysics News / / 2017 / September
Predicting Autism: Study Links Infant Brain Connections to Diagnoses at Age 2
In two previous studies, University of North Carolina researchers and colleagues linked infant brain anatomy differences to autism diagnoses at age two. Now they show differences in functional connections between brain regions at 6 months to predict autism at age two.
Located in Biochemistry and Biophysics News / / 2017 / June
Pregnant women should be included in Zika virus vaccine research, new guidance says
The inclusion of pregnant women in Zika virus vaccine research is crucial to solving the international health crisis, according to new guidance published by UNC’s Center for Bioethics and two other universities.
Located in Biochemistry and Biophysics News / / 2017 / July
Preliminary Data from Groundbreaking Genome Editing Clinical Trial Encouraging
As part of the phase 1 clinical trial for patients with Hunter syndrome, Joseph Muenzer, MD, PhD, performed the UNC Clinical Translational and Research Center's first-ever in vivo genome editing therapy, achieving a milestone in his own career.
Located in Biochemistry and Biophysics News / / 2018 / September
Promising results found for treatment of melanoma in the brain
At the American Society of Clinical Oncology Annual Meeting 2017 in Chicago, researchers presented promising data for two different investigational drug regimens used to treat melanoma that has spread to the brain, a common and deadly complication of this cancer.
Located in Biochemistry and Biophysics News / / 2017 / June
Research Reveals New Molecular Player in Heart Enlargement Due to Cardiac Disease
UNC School of Medicine researchers led by Jiandong Liu, PhD, found that an RNA-binding protein called Lin28 is crucial for pathological hypertrophy, an enlargement of the heart associated with diverse cardiac diseases.
Located in Biochemistry and Biophysics News / / 2019 / January
Researchers continue to seek strategy for starving brain tumors
In the journal Cancer Research, UNC Lineberger researchers led by member Timothy R. Gershon, MD, PhD, report in the latest in a series of attempts to shut down the energy production machinery in medulloblastoma, the most common malignant brain tumor in children. The findings may help researchers identify a suitable therapeutic target within the sugar metabolism pathway, and provide clues to a scientific mystery surrounding the confounding way that some cancer cells get energy from sugar.
Located in Biochemistry and Biophysics News / / 2017 / June
Researchers identify anorexia nervosa genetic variants, redefine disorder as metabolic and psychiatric
The large-scale genome-wide association study, led by UNC’s Cynthia M. Bulik, PhD, FAED, founding director of the UNC Center of Excellence for Eating Disorders, and Gerome Breen, PhD, of King’s College London suggests that the origins of the eating disorder include a combination of metabolic and psychiatric components.
Located in Biochemistry and Biophysics News / / 2019 / July
Researchers Link Specific Protein Mutations to Ataxia Disease Symptoms
Jonathan Schisler, MS, PhD, led research showing that limiting the activity of a mutant CHIP protein could decrease symptom severity for people with cerebral ataxia, a debilitating disease of the nervous system.
Located in Biochemistry and Biophysics News / / 2019 / November
Researchers Pinpoint Animal Model Proteins Important in Study of Human Disease
Frank Conlon, PhD, co-led a study showing which proteins and pathways are conserved in four major animal models and humans, providing insights into which models are best for specific research of human disease.
Located in Biochemistry and Biophysics News / / 2019 / September