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February 3, 2022

UNC’s Cryo-EM Core facility develops new methodology for high-speed and high-resolution cryogenic electron microscopy technology

UNC researchers optimized the function of a microscope for cryogenic electron microscopy (CryoEM) to maximize the throughput and performance of the microscope housed in the UNC Chapel Hill Cryo-EM Core Facility. This method development is demonstrated successful for structural studies of GPCRs, a large group of signaling proteins that includes many therapeutic targets with unknown structures.