March 9, 2026
A North Carolina Mother Struggling with Lupus for Years Finds Relief at UNC School of Medicine
Groundbreaking CAR-T cell clinical trial led by Saira Sheikh, MD, showcased on national television.
Category: Clinical Research
February 4, 2026
UNC Researchers Awarded $7.3 Million to Advance Research on Rare Bronchiectatic Diseases
UNC researchers have received ~$7.3M from NHLBI to lead the Rare Bronchiectatic Diseases Consortium, advancing research on four rare lung diseases that cause progressive bronchiectasis. The effort builds on UNC’s national leadership and aims to accelerate discovery, clinical trials, and new therapies for underserved patient populations.
January 28, 2026
UNC Study Shows CAR T-Cell Therapy Improves Symptoms of Myasthenia Gravis
The clinical trial, led by James Howard Jr., MD., shows that a single course of six once-weekly infusions of Descartes-08 resulted in sustained clinically meaningful responses among patients with generalized myasthenia gravis.
January 5, 2026
The Year in Research
In fiscal year 2025, UNC School of Medicine researchers led the drive toward important discoveries aimed at improving human health and the lives of people in North Carolina. Our researchers remain dedicated to UNC’s broader research missions by preventing and curing disease, optimizing brain health and well-being, and applying artificial intelligence to benefit and save lives.
December 18, 2025
UNC Awarded Funding To Implement Useful Research Results to Prevent Childhood Obesity
This project is co-led by Dual Principal Investigators Dr. Kori Flower at the University of North Carolina at Chapel Hill and Dr. Eliana Perrin at The Johns Hopkins University.
October 20, 2025
Digital Health Outreach Improves Lung Cancer Screening
A new multi-site study, co-led by researchers at the UNC Lineberger Comprehensive Cancer Center and Wake Forest University School of Medicine, has demonstrated that a direct-to-patient digital health program can significantly increase recommended lung cancer screening for high-risk individuals.
October 15, 2025
New Secure Cloud Computing Environment to Change How Researchers Work with UNC Health Electronic Health Record Data
In a joint effort to modernize our clinical data research infrastructure, UNC School of Medicine, NC TraCS Institute, and UNC Health have built the new Secure Health Informatics Research Environment (SHIRE). The SHIRE, going live on November 3, is a full-featured analytics platform designed to meet the needs of a wide variety of projects using data from UNC Health’s electronic health record.
May 29, 2025
UNC Researchers Help Marion Family Affected by Rare Mosquito Disease
Five-year-old Granger Horney contracted the La Crosse Virus, a potentially deadly mosquito-borne disease, in July 2024. With blood samples from Granger, researchers at Carolina are working to create better diagnostics and a treatment for the little-known disease.
March 10, 2025
Therapy for Perinatal Asphyxia Does Not Benefit Preterm Infants, Study Finds
A national multi-site clinical trial, co-led by researchers at the UNC School of Medicine, has found that therapeutic hypothermia may be harming preterm infants recovering from a specific type of brain injury.
October 15, 2024
UNC School of Medicine, BioXcel Therapeutics Team Up to Tackle Acute Stress Disorder
U.S. Department of Defense awarded $2.8 million to UNC Institute for Trauma Recovery researchers led by Samuel McLean, MD, to test the safety and efficacy of BXCL501 – sublingual dexmedetomidine created by BioXcel Therapautics for treating acute stress reaction symptoms and preventing posttraumatic stress.
September 25, 2024
UNC Fast-Tracks Personalized Treatment for Twins with Ultra Rare Genetic Disorder
In May 2022, Yael Shiloh-Malawsky, MD, a neurologist at the UNC School of Medicine, met two new patients combatting a rare and fatal neurodegenerative disorder called Batten disease. With help from UNC, the twin girls were able to get personalized treatment from bench to bedside in record time.
July 24, 2024
Wearable Devices Can Increase Health Anxiety. Could They Adversely Affect Health?
For patients with atrial fibrillation, using a wearable device can lead to higher rates of anxiety about their Afib symptoms and treatment, doctor visits, and use of informal healthcare resources, according to a new study from UNC School of Medicine researchers led by Lindsey Rosman, PhD.