Genetics And Aging Archives

Researchers pinpoint small molecules that greatly affect differences in heart health in men and women.

Building off previous groundbreaking research, a new study identifies specific genetic variants that have significant impacts on brain development and are shared across eight different psychiatric disorders. Targeting these variants could pave the way for treatments that address multiple conditions at once.

A research team led by Daniel McKay, PhD, associate professor in the Departments of Biology and Genetics, has identified a key focal point in the biological processes that control cell identity and can lead to disease when mutated.

Chris Sayed, MD, professor of dermatology, Yun Li, PhD, professor of genetics and biostatistics, and Karen Mohlke, PhD, professor of genetics, were awarded $2.3 million from the National Institute of Arthritis, Musculoskeletal and Skin Diseases to study the genetic basis of a chronic skin condition called hidradenitis suppurativa.

The lab of Jason Stein, PhD, associate professor of genetics and member of the UNC Neuroscience Center, has created a controlled model system that could help researchers identify the context-dependent functions of genetic variants that increase one’s risk for developing a psychiatric disorder, such as schizophrenia.

UNC School of Medicine researchers Mohanish Deshmukh, PhD, professor of cell biology and physiology, and Praveen Sethupathy, PhD, a former professor of genetics and current chair of Biomedical Sciences at Cornell University, show that a molecule called miR-29 is instrumental in driving the aging process.

A new review article written by Patrick Sullivan, MD, FRANZCP, the Yeargan Distinguished Professor of Psychiatry and Genetics, outlines the genetic foundations for schizophrenia.

Researchers in the lab of Jenny Ting, PhD, the William Kenan Distinguished Professor of Genetics and professor of microbiology and immunology, have made numerous findings about how cell death from SARS-CoV-2 infection may directly influence disease progression.

A woman with blonde hair and a white lab coat stands with hands in her pockets

A research study named Early Check has screened 1,000 newborns after birth in an effort to help identify rare conditions early, provide treatment, give parents educational information, and connect families with specialists throughout the state of North Carolina.

Springer recently released "Chronic Illness Care, Principles and Practice," edited by UNC Family Medicine's Timothy P. Daaleman, DO, MPH, and Margaret R. Helton, MD. Faculty members in the Department of Family Medicine, faculty across the UNC-Chapel Hill campus, and other national and international experts wrote the textbook.

UNC School of Medicine’s Patrick Sullivan, MD, FRANZCP, and a team of scientists in the Psychiatric Genetic Consortium have created a new manual researchers can use to learn more about the origins of human diseases with high genetic risk.

Keriayn Smith, PhD, receives $665,786 over the course of four years to research non-coding RNA in yeast, mammalian cells, and more.

Category: Genetics And Aging

MicroRNA Responsible for Sex Differences in Cardiac Physiology, Disease

Eight Psychiatric Disorders Share the Same Genetic Causes, Study Says

UNC Scientists Discover New Details of Gene Regulation

UNC School of Medicine Researchers Take on Chronic Skin Condition

Researchers Create New System to Decode Genetic Risk for Psychiatric Disorders

Small RNA Molecule Discovered to Have Role in Driving Aging

Researchers Highlight the Genetic Complexity of Schizophrenia

Study Reveals “Cell Death Cascade” in Airway Cells Infected with SARS-CoV-2

A Newborn Genetic Screening Study Reaches New Milestone

UNC Department of Family Medicine Authors Second Edition of Chronic Illness Care Textbook

Mammalian Evolution Provides Hints for Understanding the Origins of Human Disease

Smith Earns NSF Grant to Study “Dark Matter” of the Genome