December 17, 2024
Using technology first designed by Bryan L. Roth, MD, PhD, the Michael Hooker Distinguished Professor of Pharmacology, researchers at the UNC School of Medicine have engineered a molecular technology that can turn off pain receptors.
June 11, 2024
Yinglong Miao, PhD, associate professor of pharmacology and computational medicine, has been named editor-in-chief of npj Drug Discover, part of the Nature portfolio of journals.
May 16, 2024
The UNC School of Medicine lab of Bryan Roth, MD, PhD, and colleagues at UCSF, Stanford and Harvard determined that a protein prediction technology can yield accurate results in the hunt to efficiently find the best possible drug candidates for many conditions.
May 13, 2024
The UNC School of Medicine lab of Zoe McElligott, PhD, and colleagues found that the animal tranquilizer xylazine activates opioid receptors in the brain, suggesting a reason why the treatment naloxone triggers a more severe withdrawal response when given to individuals on fentanyl/xylazine and suffering from respiratory depression.
May 7, 2024
Juliane Nguyen, PhD, professor and vice chair of pharmacoengineering and molecular pharmaceuticals at the UNC Eshelman School of Pharmacy, and Janelle Arthur, PhD, associate professor of microbiology and immunology at the UNC School of Medicine, have engineered a probiotic yeast to treat inflammatory bowel disease in animals.
April 10, 2024
A new study in the lab of Bryan Roth, MD, PhD, at the UNC School of Medicine, helps us better understand how we perceive bitter taste on a chemical level. The findings may lead to the development of drugs that targeting taste receptors.
March 6, 2024
In this new Vital Signs series, we feature graduate student Max Hockenberry, who performs research in the labs of Wes Legant, PhD, and Jim Bear, PhD. Hockenberry is developing new microscopy methods so researchers can measure the mechanisms cells use to maneuver through tight spaces in the body.
February 29, 2024
Klaus Hahn, PhD, the Ronald G. Thurman Distinguished Professor of Pharmacology at the UNC School of Medicine, will co-lead this Chan Zuckerberg Initiative project with colleagues at Duke University and North Carolina State University.
January 22, 2024
Jonathan Schisler, PhD, Leon Coleman, MD, PhD, and Ben Philpot, PhD, at the UNC School of Medicine, were awarded a five-year, $675,000 grant to lead a summer undergraduate experience program promoting neuropharmacology and neurobiological disease research to be conducted by students from underrepresented groups.
January 17, 2024
Led by Juan Song, PhD, at the UNC School of Medicine, and Wubin Bai, PhD, at the UNC College of Arts and Sciences, research suggests that a wearable patch featuring electrically triggered microneedles for on-demand drug delivery could be the next frontier in treatment of neurodegenerative disorders and neurological injuries.
October 31, 2023
An international research team, including Jonathan C. Schisler, PhD, in the UNC School of Medicine, has found how SARS-CoV-2 causes widespread “energy outages” throughout major organs, and how these effects contribute to debilitating long COVID symptoms.
September 25, 2023
Kristalyn Gallagher, DO, Kevin Chen, MD, and Shawn Gomez, EngScD, in the UNC School of Medicine have developed an AI model that can predict whether or not cancerous tissue has been fully removed from the body during breast cancer surgery.