Pharmacology Archives

A new study published in Neuron, led by Juan Song, PhD, sheds light on how Alzheimer’s disease affects the brain. The findings could lead to new forms of therapy.

Experts at the UNC School of Medicine played a pivotal role in the approval of a new medication for pediatric patients that could also be used to treat other types of cancer.

Published in Neuron, new research demonstrates how a high-fat diet, even short-term, can rapidly affect brain health, but there are ways to reverse this and prevent long-term cognitive decline.

Experts at the UNC School of Medicine and UNC Eshelman School of Pharmacy are focused on a pain drug candidate that can target an area of the brain that controls the ‘unpleasantness’ associated with pain.

Rahima Benhabbour, PhD, a tenured associate professor of biomedical engineering, is developing the first 3D-printed intravaginal ring, revolutionizing how women receive treatments for infertility, HIV, menopause, and more.

Using technology first designed by Bryan L. Roth, MD, PhD, the Michael Hooker Distinguished Professor of Pharmacology, researchers at the UNC School of Medicine have engineered a molecular technology that can turn off pain receptors.

Yinglong Miao, PhD, associate professor of pharmacology and computational medicine, has been named editor-in-chief of npj Drug Discover, part of the Nature portfolio of journals.

The UNC School of Medicine lab of Bryan Roth, MD, PhD, and colleagues at UCSF, Stanford and Harvard determined that a protein prediction technology can yield accurate results in the hunt to efficiently find the best possible drug candidates for many conditions.

The UNC School of Medicine lab of Zoe McElligott, PhD, and colleagues found that the animal tranquilizer xylazine activates opioid receptors in the brain, suggesting a reason why the treatment naloxone triggers a more severe withdrawal response when given to individuals on fentanyl/xylazine and suffering from respiratory depression.

Juliane Nguyen, PhD, professor and vice chair of pharmacoengineering and molecular pharmaceuticals at the UNC Eshelman School of Pharmacy, and Janelle Arthur, PhD, associate professor of microbiology and immunology at the UNC School of Medicine, have engineered a probiotic yeast to treat inflammatory bowel disease in animals.

A new study in the lab of Bryan Roth, MD, PhD, at the UNC School of Medicine, helps us better understand how we perceive bitter taste on a chemical level. The findings may lead to the development of drugs that targeting taste receptors.

In this new Vital Signs series, we feature graduate student Max Hockenberry, who performs research in the labs of Wes Legant, PhD, and Jim Bear, PhD. Hockenberry is developing new microscopy methods so researchers can measure the mechanisms cells use to maneuver through tight spaces in the body.

Category: Pharmacology

Study Uncovers Brain Pathways Connected to Alzheimer’s Memory Loss and Mood Changes

UNC Lab Contributed to FDA Approval of First-of-its-Kind Medication for Pediatric Brain Tumor

Junk Food Puts Memory at Risk—Here’s How to Protect It

A New, Non-Addictive Painkiller is on the Horizon

Meet The Researcher Who Is Revolutionizing Women’s Health

Researchers Create Gene Therapy with Potential to Treat Peripheral Pain Conditions

Miao Named Editor-in-Chief of Nature Journal

Researchers Wrestle with Accuracy of AI Technology Used to Create New Drug Candidates

Scientists Discover Surprising Details about Xylazine in Combination with Fentanyl

Researchers Engineer Yeast to Deliver Drugs, Reduce Inflammation for Possible Inflammatory Bowel Disease Treatment

Researchers Discover How We Perceive Bitter Taste

Five Questions with Max Hockenberry