Dr. Kenneth A. Jacobson from the National Institutes of Health presents
March 18 @ 4:00 pm - 5:00 pm
Kenneth A. Jacobson, PhD
John W. Daly Distinguished Scientist
Senior Investigator
Laboratory of Bioorganic Chemistry
NIDDK, National Institutes of Health
Seminar Title: “Action of Nucleosides and Nucleotides at Purinergic and Non-Purinergic Drug Targets”
Please join us and show support for our seminar speakers!
(For those unable to attend, a zoom link is available upon request to Mimi Baltz.)
Host: Yinglong Miao
Dr. Jacobson is an established medicinal chemist with interests in the structure and pharmacology of receptors and in developing drugs that act as agonists or antagonists of G protein-coupled receptors (GPCRs). His current focus is on receptors for purines, encompassing both adenosine receptors and P2 receptors, which are activated by ATP, UTP and other extracellular nucleotides. His lab has taken an interdisciplinary approach to studying the chemical and biological aspects of these receptors. They have used convergent modeling, mutagenesis and structure activity approaches to gather information about the three-dimensional structure of the receptors and its relationship to binding and activation functions.
https://www.niddk.nih.gov/about-niddk/staff-directory/biography/jacobson-kenneth