Machine Learning Tools & Precision Medicine in Clinical Research
May 18 @ 1:00 pm - 3:00 pm
Machine Learning Tools for Clinical Researchers: A Pragmatic Approach Series
Machine learning analysis methods offer the opportunity to integrate and learn from large amounts of biological, clinical, and environmental data, and there is a growing interest in how these tools can be used to inform and individualize clinical decision making in a variety of disease areas. Machine learning can offer different, yet often complementary, insights compared to traditional statistical analyses to better understand heterogeneity in patient presentation, prognoses, and treatment response, generating critical data for precision medicine research. These methods can allow integration across diverse data types and large feature sets, overcoming some limitations of traditional tools to answer clinical questions. However, many clinical researchers have little exposure to machine learning methods, presenting a barrier to utilization of these tools themselves and/or to effective collaboration with methodologists in their own research.
The objectives of this series are to:
- Provide a background/foundation of knowledge regarding the use of machine learning tools in clinical questions
- Understand the strengths and limitations of these methods
- Recognize some real-world examples of applied machine learning methodology in clinical research
- Elucidate how machine learning can be used to advance precision medicine research
|1:00pm||Precision medicine overview and SMART trial designs and how those can be used with ML methods to infer precision medicine decision support (John Sperger)|
|1:30pm||Precision medicine machine learning analytics to improve PAD treatment decisions and outcomes (Katharine McGinigle and Nikki Freeman)|
|2:00pm||Machine learning in Epic precision medicine machine learning analytics to address diagnostic odysseys among pediatric patients with rare genetic diseases (Michael Adams and Kushal Shah)|
|2:30pm||Q&A/panel questions and discussion|
The last event in this series happens on May 25, 2022.