MHI Seminar Series presents Sharon Gerecht, Ph.D., Paul M. Gross Distinguished Professor of Biomedical Engineering; Associate Dean for Research and Infrastructure, Pratt School of Engineering, Duke University, Durham, NC
February 15 @ 10:00 am - 11:00 am
Summary of Seminar: Vascular differentiation and morphogenesis, and eventual homeostasis, occur in a complex and dynamic milieu. Two aspects of this microenvironment seem critical for blood vessel growth and stabilization: (i) the extracellular matrix, which provides critical support for vascular cell adhesion, proliferation, migration, and morphogenesis, and (ii) low oxygen concentrations (hypoxia), which is a critical factor promoting vascularization during embryonic development, injury, and tumor growth. In this talk, Dr. Gerecht will present her lab’s recent efforts to develop and use engineering approaches to understand how these physicochemical cues and downstream signaling pathways impact vascular assembly, function, and regeneration, leading to fundamental knowledge and future therapeutics.
UNC Lineberger Comprehensive Cancer Center, Pagano Conference Room (LCCC 00-002)
450 West Dr.
Chapel Hill, North Carolina 27599