Ortho RaMs – Mechanics and Computational Modeling of Biological Tissues

Presented by Dr. Shadow Huang (NC State University). The mechanics of biological tissues, including both soft and hard tissues, is a multidisciplinary research area. There is a growing recognition that mathematical modeling plays a crucial role in understanding and predicting tissue growth and remodeling. These models can guide the identification and interpretation of insightful experiments and enable efficient exploration of the implications of various hypotheses. In my research group at NC State University, we employ a combination of experimental, microstructural, continuum mechanical, and computational methods to gain a deeper understanding of the relationships among tissue structure, properties, and functions. I will present examples from cardio-vascular tissues, such as venous tissue, and musculoskeletal tissues, specifically tendon-bone insertion. The in-silico models we construct in this research are verified and refined by comparing them to our in-situ biaxial mechanical testing results, making them valuable translational tools for accurately predicting the material behavior of biological tissues.

3200 Thurston Building, Dickson Conference Room
CB #7280
Chapel Hill, North Carolina 27599
United States
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