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MHI Seminar Series presents Zhong Wang, Ph.D., Associate Professor, Cardiac Surgery, University of Michigan, Ann Arbor, MI

Summary of Seminar:  Cell fate conversion is associated with extensive epigenetic and post-translational modifications (PTMs) and architectural changes of sub-organelles and organelles; yet, how these events are interconnected remains unknown. I will discuss our identification of a phosphorylation code in 14-3-3 binding motifs (PC14-3-3) that greatly stimulates induced cardiomyocyte (iCM) formation from fibroblasts. PC14-3-3 is identified … Read more