Research

The latest research news from UNC Health Care and the UNC School of Medicine.

Scan of Genomes for Inherited Variants Implicates New Gene Important in Autism

Scan of Genomes for Inherited Variants Implicates New Gene Important in Autism

Hyejung Won, PhD, and Jason Stein, PhD, in the UNC Department of Genetics and members of the UNC Neuroscience Center, led a genome-wide association study to find that lowered expression of a gene called DDHD2 may increase a person’s likelihood of autism.

Scan of Genomes for Inherited Variants Implicates New Gene Important in Autism - Read More…

UNC Researchers to Participate in International Schizophrenia Study

UNC Researchers to Participate in International Schizophrenia Study

The ProNET project aims to test whether data-driven variation in biomarkers can be used to predict individual clinical trajectories and select individual patients most likely to benefit from specific treatments. The Department of Psychiatry's Diana Perkins, MD, MPH, is the UNC principal investigator for ProNET.

UNC Researchers to Participate in International Schizophrenia Study - Read More…

Kesimer Featured as COPD Science Expert

Kesimer Featured as COPD Science Expert

The trade magazine Pulmonology Consultant asked Mehmet Kesimer, PhD, four important questions about mucin abnormalities in early COPD.

Kesimer Featured as COPD Science Expert - Read More…

A Scientific First: How Psychedelics Bind to Key Brain Cell Receptor

A Scientific First: How Psychedelics Bind to Key Brain Cell Receptor

This work, published in Cell and led by the UNC-Chapel Hill lab of Bryan L. Roth, MD, PhD, sets the stage for the discovery of new kinds of antidepressants, anti-anxiety drugs, and treatments for substance use disorders.

A Scientific First: How Psychedelics Bind to Key Brain Cell Receptor - Read More…

Ramsden, Gupta awarded 5-year, $8.8 million grant to study enzyme with important implications for breast and ovarian cancers

Ramsden, Gupta awarded 5-year, $8.8 million grant to study enzyme with important implications for breast and ovarian cancers

The National Cancer Institute has awarded a team led by UNC Lineberger’s Dale Ramsden, PhD, professor in the UNC School of Medicine Department of Biochemistry and Biophysics, a five-year, $8.8 million program project grant to study an enzyme called DNA polymerase theta.

Ramsden, Gupta awarded 5-year, $8.8 million grant to study enzyme with important implications for breast and ovarian cancers - Read More…

Researchers Reveal Safeguarding of a Key DNA Sensor in the Innate Immune System

Researchers Reveal Safeguarding of a Key DNA Sensor in the Innate Immune System

Led by Qi Zhang, PhD, and Robert McGinty, MD, PhD, UNC-Chapel Hill scientists used cryo-electron microscopy technology to produce the first-ever high-resolution structure of the protein cGAS bound to the DNA packaging unit inside human cell nuclei, revealing how cGAS responds to foreign or damaged DNA, but not the body’s healthy DNA.

Researchers Reveal Safeguarding of a Key DNA Sensor in the Innate Immune System - Read More…

The Malawian Program for Mental Health Research Training Grant has been awarded to Institute for Global Health and Infectious Diseases in partnership with UNC Psychiatry

The Malawian Program for Mental Health Research Training Grant has been awarded to Institute for Global Health and Infectious Diseases in partnership with UNC Psychiatry

The UNC Institute for Global health and Infectious Diseases and UNC Psychiatry’s Division of Global Mental Health WARMHEART will create an expert pool of mental health researchers based in Malawi who are trained as leaders and able to collaborate with other disciplines and policymakers to address the role of psychiatric illness across the lifespan in sub-Saharan Africa.

The Malawian Program for Mental Health Research Training Grant has been awarded to Institute for Global Health and Infectious Diseases in partnership with UNC Psychiatry - Read More…

UNC School of Medicine Research Featured in Midtown Magazine

In a Midtown Magazine feature titled "Triangle Hospitals Combat COVID-19," several UNC-Chapel Hill research projects were mentioned as important players in our fight against the virus.

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Linnstaedt named a 2020 Rita Allen Pain Scholar

Linnstaedt named a 2020 Rita Allen Pain Scholar

Sarah D. Linnstaedt, PhD, assistant professor in the UNC Department of Anesthesiology, has been awarded a 2020 Award in Pain grant from The Rita Allen Foundation. This prestigious award will help Dr. Linnstaedt’s lab perform studies examining a promising therapeutic target for the prevention of chronic pain.

Linnstaedt named a 2020 Rita Allen Pain Scholar - Read More…

CIDD Autism Imaging Research Published in National Geographic

CIDD Autism Imaging Research Published in National Geographic

The brains of infants who develop the disorder grow too fast, a UNC-Chapel Hill discovery that could help doctors prevent impairments before they appear.

CIDD Autism Imaging Research Published in National Geographic - Read More…

Genetics Faculty Publish Back-to-Back Papers in Cell

Genetics Faculty Publish Back-to-Back Papers in Cell

Blood-Cell Consortium members from the UNC Department of Genetics, Drs. Yun Li (associate professor), Laura Raffield (assistant professor), Karen Mohlke (professor) and Cassandra Spracklen (former postdoctoral fellow) are co-authors on two large studies focused on the genetics of blood cell traits.

Genetics Faculty Publish Back-to-Back Papers in Cell - Read More…

Patients with a Liver Transplant Aren't at Greater Risk of Death from COVID-19

Patients with a Liver Transplant Aren't at Greater Risk of Death from COVID-19

UNC's Erica Brenner, MD, A. Sidney Barritt IV, MD, and Andrew M. Moon, MD, are co-authors of the study with colleagues at Oxford University.

Patients with a Liver Transplant Aren't at Greater Risk of Death from COVID-19 - Read More…

UNC Ramps Up Convalescent Plasma Clinical Trial to Fight COVID-19

UNC Ramps Up Convalescent Plasma Clinical Trial to Fight COVID-19

On the heels of FDA authorization of convalescent plasma as a treatment for COVID-19, researchers at UNC are conducting a clinical trial to determine the safety and efficacy of plasma that includes a higher amount of neutralizing antibodies against SARS-CoV-2.

UNC Ramps Up Convalescent Plasma Clinical Trial to Fight COVID-19 - Read More…

Researching the impact of COVID-19 on families with autism

Researching the impact of COVID-19 on families with autism

On Monday, March 16th, Clare Harrop, PhD, found out that her daughters' daycare was closing. As the full impact of state and national shutdowns hit her, Harrop began to lose sleep and feel a heightened sense of anxiety. At the same time, she was thinking of the many families she works with in her research studies. She recalls texting a colleague: If I'm feeling like this, how are parents of kids with autism feeling?

Researching the impact of COVID-19 on families with autism - Read More…

UNC Researchers Publish Striking Images of SARS-CoV-2 Infected Cells

UNC Researchers Publish Striking Images of SARS-CoV-2 Infected Cells

The UNC School of Medicine lab of Camille Ehre, PhD, generated high-powered microscopic images showing startlingly high SARS-CoV-2 viral loads on human respiratory surfaces, ready to spread infection in infected individuals and transmit infection to others.

UNC Researchers Publish Striking Images of SARS-CoV-2 Infected Cells - Read More…

Scientists Show How Brain Flexibility Emerges in Infants

Scientists Show How Brain Flexibility Emerges in Infants

Cognitive flexibility, which refers to the brain’s ability to switch between mental processes in response to external stimuli and different task demands, seems to begin developing during the first two years of life, which is much earlier than previously thought. UNC BRIC researchers led by Weili Lin, PhD, used magnetic resonance imaging techniques to show the emergence of a functional flexible brain during early infancy.

Scientists Show How Brain Flexibility Emerges in Infants - Read More…

Join the COVID-19 Prevention Network Registry to Enroll in Clinical Trials

The UNC School of Medicine is recruiting participants for a phase III clinical trial of a COVID-19 vaccine in an effort to find solutions to the current pandemic. By enrolling in this study, participants will contribute to a potential solution that could solve this global health crisis.

Join the COVID-19 Prevention Network Registry to Enroll in Clinical Trials - Read More…

UNC Researchers Launch Clinical Trial for COVID-19 Treatments

UNC Researchers Launch Clinical Trial for COVID-19 Treatments

This study includes phase 2 and phase 3 elements to expedite the evaluation of treatments for adults with moderate cases of COVID-19, with the goal of preventing severe disease that can lead to hospitalizations. The principal investigator is David Wohl, MD, professor of infectious diseases at the UNC School of Medicine.

UNC Researchers Launch Clinical Trial for COVID-19 Treatments - Read More…

UNC-led Consortium to Study HIV-related Cancers in sub-Saharan Africa

UNC-led Consortium to Study HIV-related Cancers in sub-Saharan Africa

UNC researchers are partnering with colleagues at four institutions in Africa to study HIV-associated malignancies. Led by Blossom Damania, PhD, the research team received a five-year, $6-million grant from the National Cancer Institute.

UNC-led Consortium to Study HIV-related Cancers in sub-Saharan Africa - Read More…

UNC and Duke Investigators Receive a $1.5 Million Grant to Test SARS-CoV-2 Vaccines

UNC and Duke Investigators Receive a $1.5 Million Grant to Test SARS-CoV-2 Vaccines

Kristina De Paris, PhD, and Sallie Permar, MD, PhD, received a supplement from the National Institute of Allergy and Infectious Diseases to test Moderna’s mRNA vaccine and a protein vaccine designed by Kizzy Corbett and Barney Graham.

UNC and Duke Investigators Receive a $1.5 Million Grant to Test SARS-CoV-2 Vaccines - Read More…

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