Research

The latest research news from UNC Health Care and the UNC School of Medicine.

Improving Cardiovascular Health of the Most Vulnerable

Improving Cardiovascular Health of the Most Vulnerable

Heart disease and stroke are major causes of pre-mature mortality and morbidity in North Carolina, and there are significant racial and geographic disparities in cardiovascular care, morbidity and mortality. A two-year pilot project led by Rick Stouffer, MD, shows how the cardiovascular health of the most vulnerable patients can be improved with free medications.

Improving Cardiovascular Health of the Most Vulnerable - Read More…

New School of Medicine Initiative Solicits First Call for Applications for Physician Scientist Trainee Awards

New School of Medicine Initiative Solicits First Call for Applications for Physician Scientist Trainee Awards

With support from the strategic plan, the new Physician Scientist Training Program will support the most promising physician scientists and bolster translational research at the UNC School of Medicine.

New School of Medicine Initiative Solicits First Call for Applications for Physician Scientist Trainee Awards - Read More…

Nelson Receives NIAMS Grant To Apply Advanced Methodologies to Osteoarthritis (OA) Phenotyping

Nelson Receives NIAMS Grant To Apply Advanced Methodologies to Osteoarthritis (OA) Phenotyping

Dr. Amanda Nelson's $365,000, 2-year grant will facilitate much-needed research strategies designed to lead to more personalized and successful management of OA.

Nelson Receives NIAMS Grant To Apply Advanced Methodologies to Osteoarthritis (OA) Phenotyping - Read More…

Researchers find clues to drug resistance in medulloblastoma subtype

Researchers find clues to drug resistance in medulloblastoma subtype

University of North Carolina Lineberger Comprehensive Cancer Center researchers led by Timothy Gershon, MD, PhD, and Kirk Wilhelmsen, MD, PhD, have new evidence to explain how drug resistance develops in a major subtype of medulloblastoma, the most common invasive brain tumor in children.

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A Full Breakdown of All Vaping Industry Academic Scholarships to High Schoolers

A Full Breakdown of All Vaping Industry Academic Scholarships to High Schoolers

Led by Adam Goldstein, MD, UNC Family Medicine researchers published details on how electronic cigarette companies offer academic scholarships to high school-age teenagers and young adults, showing a disconnect between the industry’s desire to increase vaping among young people and the desire of health advocates to decrease such usage.

A Full Breakdown of All Vaping Industry Academic Scholarships to High Schoolers - Read More…

Life’s Clockwork: Scientist Shows How Molecular Engines Keep Us Ticking

Life’s Clockwork: Scientist Shows How Molecular Engines Keep Us Ticking

Charles Carter, PhD, published seminal work on the inner workings of chemical machines inside our cells that turn energy into action, the foundation of life.

Life’s Clockwork: Scientist Shows How Molecular Engines Keep Us Ticking - Read More…

Latest Grant Awards to SOM Faculty

View a list of recent competitive grant awards to faculty from the UNC School of Medicine.

Latest Grant Awards to SOM Faculty - Read More…

Juliano Appointed to ASCI Institutional Representatives Program

Juliano Appointed to ASCI Institutional Representatives Program

Jonathan Juliano, MD, MSPH, will serve as the UNC Institutional Representative as part of the American Society for Clinical Investigation’s Institutional Representatives Program for the next 5 years.

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Research Round-Up Highlights of 2019

The SOM Office of Research releases this inaugural publication with the most noteworthy 1-2 research highlights provided by each Department.

Research Round-Up Highlights of 2019 - Read More…

Which Is More Effective for Treating PTSD:  Medication, or Psychotherapy?

Which Is More Effective for Treating PTSD: Medication, or Psychotherapy?

A systematic review and meta-analysis led by Jeffrey Sonis, MD, MPH, of UNC’s departments of social medicine and family medicine, finds there is insufficient evidence at present to answer that question. Clinicians should make shared decisions with patients about treatment, and they should not rely on current treatment guidelines.

Which Is More Effective for Treating PTSD: Medication, or Psychotherapy? - Read More…

What Happens When Your Immune System and Antibiotics Don't Work together?

What Happens When Your Immune System and Antibiotics Don't Work together?

Research from the lab of Brian Conlon, PhD, shows that as the innate immune system attacks Staphylococcus aureus, the immune system also stops antibiotics from being able to efficiently kill. This antagonism may lead antibiotics to fail.

What Happens When Your Immune System and Antibiotics Don't Work together? - Read More…

Scientists Show How Tiny, Mutated Neuron Antennae Impair Brain Connectivity

Scientists Show How Tiny, Mutated Neuron Antennae Impair Brain Connectivity

UNC School of Medicine scientists led by Eva Anton, PhD, found that defective primary cilia can modulate connectivity between neurons during brain development and cause rare neurodevelopmental conditions called Joubert-syndrome related disorders.

Scientists Show How Tiny, Mutated Neuron Antennae Impair Brain Connectivity - Read More…

Scientists Visualize Competition Between Healthy, Dysfunctional Platelets

Scientists Visualize Competition Between Healthy, Dysfunctional Platelets

In some patients with blood disorders, platelet transfusion therapy doesn’t work. UNC School of Medicine scientists used real-time imaging and mouse models to show why. Their work, led by Wolfgang Bergmeier, PhD, could guide clinical studies and better use of platelet therapy.

Scientists Visualize Competition Between Healthy, Dysfunctional Platelets - Read More…

Weiss Will Lead PDS Biotechnology Combination Studies in Cancer

Weiss Will Lead PDS Biotechnology Combination Studies in Cancer

PDS Biotechnology has appointed Jared Weiss, MD, principal investigator for combination trials with Merck, to advance studies in head, neck and HPV-related advanced cancer.

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Niznik Leads Study That Identifies Benefits of De-prescribing AChEls

Niznik Leads Study That Identifies Benefits of De-prescribing AChEls

Assistant professor Joshua Niznik, PhD, PharmD, in the division of Geriatric Medicine, published a study in the Journal of the American Geriatrics Society that suggests de-prescribing Acetylcholinesterase Inhibitors (AChEls) as a reasonable approach to lowering polypharmacy.

Niznik Leads Study That Identifies Benefits of De-prescribing AChEls - Read More…

Largest study of its kind reveals that many psychiatric disorders  arise from common genes

Largest study of its kind reveals that many psychiatric disorders arise from common genes

Several UNC School of Medicine faculty from the departments of Genetics and Psychiatry are co-authors of the study, which was published in the journal Cell.

Largest study of its kind reveals that many psychiatric disorders arise from common genes - Read More…

How Enzymes Reign Supreme in Worldwide Carbon Recycling

How Enzymes Reign Supreme in Worldwide Carbon Recycling

Richard Wolfenden, PhD, professor of biochemistry and biophysics, details how white rot fungi produce enzymes that turn out to be key players in the carbon cycle.

How Enzymes Reign Supreme in Worldwide Carbon Recycling - Read More…

First U.S. Study Shows Strong Results for Minimally Invasive Procedure to Treat Knee Pain from Osteoarthritis

First U.S. Study Shows Strong Results for Minimally Invasive Procedure to Treat Knee Pain from Osteoarthritis

Ari Isaacson, MD, director of clinical research in the UNC School of Medicine’s department of radiology, led a pilot study to investigate the effectiveness of using genicular artery embolization for long-term treatment of knee pain caused by osteoarthritis.

First U.S. Study Shows Strong Results for Minimally Invasive Procedure to Treat Knee Pain from Osteoarthritis - Read More…

Machine Learning Helps Scientists Measure Important Inflammation Process

Machine Learning Helps Scientists Measure Important Inflammation Process

Led by the UNC School of Medicine lab of Leslie Parise, PhD, researchers created an artificial intelligence tool to measure NETosis, an important inflammatory process by which certain white blood cells trap invaders like bacteria. This work will help scientists find ways to stop or promote the process in disease states.

Machine Learning Helps Scientists Measure Important Inflammation Process - Read More…

Barnes Presentation Designated a Presidential Poster at ACG Annual Meeting

Barnes Presentation Designated a Presidential Poster at ACG Annual Meeting

Edward L. Barnes, MD, MPH, assistant professor in the division of gastroenterology and hepatology, also won an Outstanding Presenter Award for this research.

Barnes Presentation Designated a Presidential Poster at ACG Annual Meeting - Read More…

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