Doris Duke Charitable Foundation: Sickle Cell Disease/Advancing Cures

The Doris Duke Charitable Foundation (DDCF) has announced a new funding opportunity focused on providing grants to advance curative approaches for sickle cell disease including, gene modification and drug therapies to restore hemoglobin function. Award amount is up to $900,000 over three (3) years. The application deadline is May 25, 2017 by 3:00pm EST.

The Office of Corporate and Foundation Relations has identified the following private funding opportunity:

Doris Duke Charitable Foundation: Sickle Cell Disease/Advancing Cures
http://www.ddcf.org

The Doris Duke Charitable Foundation (DDCF) has announced a new funding opportunity focused on providing grants to advance curative approaches for sickle cell disease including, gene modification and drug therapies to restore hemoglobin function. Research studies of interest include, but are not limited to:

  •  Therapeutic agents to restore hemoglobin function
  • Methods or approaches to maximize procurement of hematopoietic stem cells from patients with sickle cell disease for ex vivo manipulation
  • Approaches to maximize the rate of genetic correction of hematopoietic stem cells with available gene therapies for long-term benefit and to minimize off-target effects
  • Testing of safer bone marrow conditioning regimens to minimize toxicity in patients with sickle cell disease
  • Determinants of hematopoietic stem cell engraftment in patients with sickle cell disease

DDCF encourages crossover of researchers from other disciplines and specialties to work on sickle cell disease. Applicants must propose a clinical research project that meets the foundation’s definition: the scientific investigation of the etiology, prevention, diagnosis, or treatment of human disease using human subjects, human populations or materials of human origin. Included in the definition are studies that utilize tissues or pathogens only if they can be linked to a patient. Please note that DDCF does not support research with non-human animals. Eligible applicants must hold an advanced doctoral degree (PhD, MD, MD/PhD, DO or equivalent) and have a full-time faculty rank appointment ((Instructor, Assistant Professor, Associate Professor, or Professor). Only one application per Principal Investigator is allowed; however, an investigator may be considered part of the key personnel of another application. Applications may be submitted by an individual principal investigator or by teams of up to two principal investigators who will be co-equals sharing the responsibility for leading and directing the research project. In the case of a team application, choose one of the principal investigators to submit the application; this person will be DDCF’s point of contact for the application and grant, if awarded. Awards are made to the institution, not the individual. Indirect costs may not exceed 10% of annual total direct cost, including equipment.

Application Deadline: May 25, 2017 by 3:00pm EST. Application Guidelines for the award: http://www.ddcf.org/globalassets/medicalresearch/scd-ac/2017-scd-ac/2017-scd-ac-rfa.pdf.

If you have any questions about this funding opportunity, please contact Brooke Church, Senior Director of Corporate and Foundation Relations for Health Affairs, at Brooke_Church@unc.edu or (919) 962-0024. The UNC Office of Corporate and Foundation Relations is available to provide assistance in pursuing privately funded opportunities. 

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