Vital Signs

This week's collection of news and events from the School of Medicine

Black women with breast cancer experience delayed, longer treatment than whites, study finds

Black women with breast cancer experience delayed, longer treatment than whites, study finds

One in seven black women with breast cancer had delays in starting treatment, and black women also had extended duration of treatment, according to a study led by UNC Lineberger Comprehensive Cancer Center researchers Melissa Troester, PhD, and Marc Emerson, PhD.

Black women with breast cancer experience delayed, longer treatment than whites, study finds - Read More…

Lack of Key Neuropeptide Induces Neuroinflammation to Impair Neural Stem Cells and Limit New Neuron Production

Lack of Key Neuropeptide Induces Neuroinflammation to Impair Neural Stem Cells and Limit New Neuron Production

Published in Neuron, research from the UNC School of Medicine lab of Juan Song, PhD, determined the cell-signaling role of a neuropeptide called cholecystokinin, which is important in regulating neural stem cells and creating adult-born neurons within the hippocampus of the brain.

Lack of Key Neuropeptide Induces Neuroinflammation to Impair Neural Stem Cells and Limit New Neuron Production - Read More…

Ramsden, Gupta awarded 5-year, $8.8 million grant to study enzyme with important implications for breast and ovarian cancers

Ramsden, Gupta awarded 5-year, $8.8 million grant to study enzyme with important implications for breast and ovarian cancers

The National Cancer Institute has awarded a team led by UNC Lineberger’s Dale Ramsden, PhD, professor in the UNC School of Medicine Department of Biochemistry and Biophysics, a five-year, $8.8 million program project grant to study an enzyme called DNA polymerase theta.

Ramsden, Gupta awarded 5-year, $8.8 million grant to study enzyme with important implications for breast and ovarian cancers - Read More…

A Scientific First: How Psychedelics Bind to Key Brain Cell Receptor

A Scientific First: How Psychedelics Bind to Key Brain Cell Receptor

This work, published in Cell and led by the UNC-Chapel Hill lab of Bryan L. Roth, MD, PhD, sets the stage for the discovery of new kinds of antidepressants, anti-anxiety drugs, and treatments for substance use disorders.

A Scientific First: How Psychedelics Bind to Key Brain Cell Receptor - Read More…

Researchers Reveal Safeguarding of a Key DNA Sensor in the Innate Immune System

Researchers Reveal Safeguarding of a Key DNA Sensor in the Innate Immune System

Led by Qi Zhang, PhD, and Robert McGinty, MD, PhD, UNC-Chapel Hill scientists used cryo-electron microscopy technology to produce the first-ever high-resolution structure of the protein cGAS bound to the DNA packaging unit inside human cell nuclei, revealing how cGAS responds to foreign or damaged DNA, but not the body’s healthy DNA.

Researchers Reveal Safeguarding of a Key DNA Sensor in the Innate Immune System - Read More…