A research collaboration between clinical and preclinical investigators in the Department of Psychiatry at the UNC School of Medicine, led by Leslie Morrow, PhD, found that a drug for post-partum depression works by inhibiting systemic inflammatory pathways.

UNC School of Medicine researchers led by Flavio Frohlich, PhD, are the first to use transcranial alternating current brain stimulation (tACS) to significantly reduce symptoms in people diagnosed with major depression.

The findings of the integrated analysis from one phase 2 and two phase 3 pivotal trials were published today in The Lancet. Lead author Samantha Meltzer-Brody, MD, MPH, of the UNC School of Medicine said the promising results mark a major step forward in women’s health care.

Patrick Sullivan, MD, made international news with a study he contributed to that uncovered 30 new genes linked to depression, tripling the number known to play a role in the debilitating disease.

The study, co-led by Patrick Sullivan of UNC and Naomi Wray of the University of Queensland, is the largest genome-wide association study to date of genetic risk factors for major depression.

CHAPEL HILL - A specific genetic variation may be tied to an increased risk for severe premenstrual depression, scientists at the University of North Carolina at Chapel Hill and the National Institute of Mental Health have found.

Tag: Depression

Researchers Uncover Mechanisms of Brexanolone and the Role of Inflammation in Post-partum Depression

Brain Stimulation Improves Depression Symptoms, Restores Brain Waves in Clinical Study

Investigational Treatment for Postpartum Depression Consistently Reduced Symptoms Across Three Trials, Supporting Submission for FDA Approval

Sullivan makes international news with new study on genes and depression

Researchers identify 44 genomic variants associated with depression

Study finds hereditary link to premenstrual depression