The UNC School of Medicine lab of Bryan Roth, MD, PhD, and colleagues at UCSF, Stanford and Harvard determined that a protein prediction technology can yield accurate results in the hunt to efficiently find the best possible drug candidates for many conditions.

Juliane Nguyen, PhD, professor and vice chair of pharmacoengineering and molecular pharmaceuticals at the UNC Eshelman School of Pharmacy, and Janelle Arthur, PhD, associate professor of microbiology and immunology at the UNC School of Medicine, have engineered a probiotic yeast to treat inflammatory bowel disease in animals.

A new study in the lab of Bryan Roth, MD, PhD, at the UNC School of Medicine, helps us better understand how we perceive bitter taste on a chemical level. The findings may lead to the development of drugs that targeting taste receptors.

Klaus Hahn, PhD, the Ronald G. Thurman Distinguished Professor of Pharmacology at the UNC School of Medicine, will co-lead this Chan Zuckerberg Initiative project with colleagues at Duke University and North Carolina State University.

Jonathan Schisler, PhD, Leon Coleman, MD, PhD, and Ben Philpot, PhD, at the UNC School of Medicine, were awarded a five-year, $675,000 grant to lead a summer undergraduate experience program promoting neuropharmacology and neurobiological disease research to be conducted by students from underrepresented groups.

An international research team, including Jonathan C. Schisler, PhD, in the UNC School of Medicine, has found how SARS-CoV-2 causes widespread “energy outages” throughout major organs, and how these effects contribute to debilitating long COVID symptoms.

A comprehensive UC San Francisco-led study flagged drug components in need of more rigorous review to be sure they are safe. The UNC School of Medicine lab of Bryan Roth, MD, PhD, conducted important screening studies to confirm the findings.

Funded by the Defense Advanced Research Projects Agency (DARPA), a team of internationally acclaimed researchers led by UNC School of Medicine’s Bryan L. Roth, MD, PhD, aims to create new medications to effectively and rapidly treat depression, anxiety, and substance abuse without major side effects.

Tag: Pharmacology

Researchers Wrestle with Accuracy of AI Technology Used to Create New Drug Candidates

Researchers Engineer Yeast to Deliver Drugs, Reduce Inflammation for Possible Inflammatory Bowel Disease Treatment

Researchers Discover How We Perceive Bitter Taste

Hahn Awarded CZI Grant to Monitor, Manipulate Proteins Important in Nervous System Function, Neurological Disease

UNC School of Medicine Researchers Awarded Grant for Summer Undergraduate Experience Program

Researchers Show SARS-Cov-2 Infection Affects Energy Stores in the Body, Causing Organ Failure

Some ‘Inert’ Drug Ingredients May Be Biologically Active

Roth Leads $26.9 Million Project to Create Better Psychiatric Medications