The study shows that drug citarinostat can awaken hidden HIV, advancing efforts towards a potential cure for the complex virus.

The prestigious honor recognizes biochemist Jean Cook, PhD, and her work on cancer development and the human cell cycle, a biological process crucial for development, healing, and continued maintenance of the body.

The research, led by Nobel laureate and biochemist Aziz Sancar, MD, PhD, could revolutionize treatments for glioblastoma, an aggressive and deadly form of brain cancer.

Dissociation of G protein from drug-bound GPCR (orange) is captured in accelerated molecular dynamics simulations, starting from the bound (blue) to free state (red), with a trace of its C-terminal residue colored in a blue-white-red scale.

UNC researchers discovered how a key step in cell signaling works by showing exactly how G proteins detach from receptors that many common medicines target.

Experts at the UNC School of Medicine played a pivotal role in the approval of a new medication for pediatric patients that could also be used to treat other types of cancer.

Published in Neuron, new research demonstrates how a high-fat diet, even short-term, can rapidly affect brain health, but there are ways to reverse this and prevent long-term cognitive decline.

Experts at the UNC School of Medicine and UNC Eshelman School of Pharmacy are focused on a pain drug candidate that can target an area of the brain that controls the ‘unpleasantness’ associated with pain.

Rahima Benhabbour, PhD, a tenured associate professor of biomedical engineering, is developing the first 3D-printed intravaginal ring, revolutionizing how women receive treatments for infertility, HIV, menopause, and more.

Using technology first designed by Bryan L. Roth, MD, PhD, the Michael Hooker Distinguished Professor of Pharmacology, researchers at the UNC School of Medicine have engineered a molecular technology that can turn off pain receptors.

The UNC School of Medicine lab of Bryan Roth, MD, PhD, and colleagues at UCSF, Stanford and Harvard determined that a protein prediction technology can yield accurate results in the hunt to efficiently find the best possible drug candidates for many conditions.

Juliane Nguyen, PhD, professor and vice chair of pharmacoengineering and molecular pharmaceuticals at the UNC Eshelman School of Pharmacy, and Janelle Arthur, PhD, associate professor of microbiology and immunology at the UNC School of Medicine, have engineered a probiotic yeast to treat inflammatory bowel disease in animals.

A new study in the lab of Bryan Roth, MD, PhD, at the UNC School of Medicine, helps us better understand how we perceive bitter taste on a chemical level. The findings may lead to the development of drugs that targeting taste receptors.

Tag: Pharmacology

UNC Researchers Demonstrate Drug’s Effectiveness in Drawing Out Dormant HIV from Immune Cells

Cook Elected to 2025 AAAS Class of Honorary Fellows

UNC Researchers Show Combination Therapy Effective for Brain Cancer

UNC Scientists Discover How a Critical Signaling Step Works Inside Cells

UNC Lab Contributed to FDA Approval of First-of-its-Kind Medication for Pediatric Brain Tumor

Junk Food Puts Memory at Risk—Here’s How to Protect It

A New, Non-Addictive Painkiller is on the Horizon

Meet The Researcher Who Is Revolutionizing Women’s Health

Researchers Create Gene Therapy with Potential to Treat Peripheral Pain Conditions

Researchers Wrestle with Accuracy of AI Technology Used to Create New Drug Candidates

Researchers Engineer Yeast to Deliver Drugs, Reduce Inflammation for Possible Inflammatory Bowel Disease Treatment

Researchers Discover How We Perceive Bitter Taste