MHI Seminar Series presents MHI Keynote Speaker: Rajan Jain, M.D., William Wikoff Smith Associate Professor, Dept of Medicine and Cell & Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
Summary of Seminar: The Jain Laboratory’s work broadly falls into two major themes. First, they are defining the molecular factors regulating 3D chromatin spatial positioning. Their work was the first to show that lamina-chromatin interactions are required for lineage restriction and cellular differentiation in mammals. They demonstrated that pathogenic LMNA variants impact cell type-specific lamina-chromatin … Read more