MHI Seminar Series presents MHI Keynote Speaker: Federica Accornero, PhD, Associate Professor, Molecular Biology, Cell Biology, and Biochemistry, Brown University, Providence, RI
The Carolina Club, George Watts Hill Alumni Center 150 Stadium Drive, Chapel Hill, NC, United StatesSummary of Seminar: Gene expression fluctuations are critical for muscle homeostasis and the response to environmental insults. Yet, little is known about post-transcriptional mechanisms regulating such fluctuations while impacting muscle proteome. Genome-wide analysis of mRNA methyladenosine (m6A) revealed the dynamics of this modification during stress (PMIDs: 35013323, 33188779). We demonstrated that METTL3 (the m6A-forming enzyme; PMIDs: … Read more