Genetics

The latest genetics news from UNC Health Care and the UNC School of Medicine.

A new era for genetic interpretation

A new era for genetic interpretation

UNC Lineberger researchers are collaborating through the ClinGen consortium to pinpoint disease-causing genetic variants.

A new era for genetic interpretation - Read More…

UNC Lineberger sequences 10,000 tumors as part of national cancer genomics effort

UNC Lineberger sequences 10,000 tumors as part of national cancer genomics effort

UNC sequenced the RNA for 10,000 tumor samples as part of The Cancer Genome Atlas project, a National Cancer Institute and National Human Genome Research Institute backed effort to create a comprehensive atlas of the genetic changes in cancer.

UNC Lineberger sequences 10,000 tumors as part of national cancer genomics effort - Read More…

Genetically speaking, mammals are more like their fathers

Genetically speaking, mammals are more like their fathers

A first of its kind study shows that who we inherit genetic variants from – our mother or father – is crucial for the development of diseases and for research studies aimed at finding causes and potential treatments.

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Kelada recognized by National Institute of Environmental Health Sciences

Kelada recognized by National Institute of Environmental Health Sciences

Samir Kelada, PhD, assistant professor, Department of Genetics, was one of six scientists across the nation to receive the Outstanding New Environmental Scientist (ONES) award.

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Largest ever genome-wide study on body fat and BMI strengthen genetic links to obesity

Largest ever genome-wide study on body fat and BMI strengthen genetic links to obesity

UNC researchers led by Karen Mohlke, PhD, and Kari North, PhD, including a consortium of researchers, find 89 new genetic locations that will help scientists pinpoint genes that play roles in different obesity traits.

Largest ever genome-wide study on body fat and BMI strengthen genetic links to obesity - Read More…

Bubonic Bottleneck: UNC scientists overturn dogma on the plague

Bubonic Bottleneck: UNC scientists overturn dogma on the plague

The current outbreak of the plague in Madagascar shines a light on the need for new approaches to treat the ancient pathogen. A new UNC study unexpectedly unravels a long-held theory on how a fleabite leads to infection.

Bubonic Bottleneck: UNC scientists overturn dogma on the plague - Read More…

Epigenetic Breakthrough: A first of its kind tool to study the histone code

Epigenetic Breakthrough: A first of its kind tool to study the histone code

Scientists from UNC-Chapel Hill have created a new way to investigate epigenetic mechanisms important in diseases ranging from Alzheimer’s to cancers.

Epigenetic Breakthrough: A first of its kind tool to study the histone code - Read More…

R2d2 beats Mendel: scientists discover a selfish gene that breaks the ‘law of segregation’

R2d2 beats Mendel: scientists discover a selfish gene that breaks the ‘law of segregation’

The finding has implications for the field of evolutionary genetics and biomedical science, including new ways to research human conditions, such as Down syndrome.

R2d2 beats Mendel: scientists discover a selfish gene that breaks the ‘law of segregation’ - Read More…

Researchers pinpoint two genes that trigger severest form of ovarian cancer

Researchers pinpoint two genes that trigger severest form of ovarian cancer

UNC geneticists led by Terry Magnuson, PhD, and Ron Chandler, PhD, create the first mouse model of ovarian clear cell carcinoma; show how a known drug can suppress tumor growth.

Researchers pinpoint two genes that trigger severest form of ovarian cancer - Read More…

Women who experience postpartum depression symptoms before giving birth may face greater risk

Women who experience postpartum depression symptoms before giving birth may face greater risk

Postpartum depression (PPD) may have a diverse clinical presentation and this has critical implications for diagnosis, treatment and understanding the underlying biology of the illness, a new study finds.

Women who experience postpartum depression symptoms before giving birth may face greater risk - Read More…

Evans co-authors commentary in JAMA

Evans co-authors commentary in JAMA

UNC Lineberger Comprehensive Cancer Center member Jim Evans, MD, PhD, Bryson Distinguished Professor of Genetics and Medicine and director of clinical cancer genetics, has co-authored a commentary in the Journal of the American Medical Association (JAMA) on proposed US Food and Drug Administration (FDA) regulation of genetic testing.

Evans co-authors commentary in JAMA - Read More…

UNC School of Medicine researchers elected AAAS fellows

UNC School of Medicine researchers elected AAAS fellows

The scientists join 65 UNC colleagues as fellows of the American Association for the Advancement of Science.

UNC School of Medicine researchers elected AAAS fellows - Read More…

Improved mouse model will accelerate research on potential Ebola vaccines, treatments

Improved mouse model will accelerate research on potential Ebola vaccines, treatments

UNC researchers and colleagues are the first to develop a mouse model that more accurately reflects human disease symptoms; they found a single gene crucial for disease severity.

Improved mouse model will accelerate research on potential Ebola vaccines, treatments - Read More…

The Geneticist

The Geneticist

With his selection to the NIH Council of Councils, Terry Magnuson, PhD, becomes the first UNC scientist appointed to the board dedicated to funding the biggest ideas in medical research.

The Geneticist - Read More…

 Largest cancer genetic analysis reveals new way of classifying cancer

Largest cancer genetic analysis reveals new way of classifying cancer

The work, led by researchers at the UNC Lineberger Comprehensive Cancer Center, UNC-Chapel Hill and other TCGA sites, revamps traditional ideas of how cancers are diagnosed and treated and could also have a profound impact on the future landscape of drug development.

Largest cancer genetic analysis reveals new way of classifying cancer - Read More…

UNC researchers pinpoint new role for enzyme in DNA repair, kidney cancer

UNC researchers pinpoint new role for enzyme in DNA repair, kidney cancer

The discovery, from the lab of Brian Strahl, PhD, offers insights for the creation of better, more targeted therapies for various forms of cancer.

UNC researchers pinpoint new role for enzyme in DNA repair, kidney cancer - Read More…

Scientists visit 8,400 North Carolina students

Scientists visit 8,400 North Carolina students

‘Science ambassadors’ deploy across the state for annual DNA Day celebration, inspiring students to break stereotypes, ask questions and dream big.

Scientists visit 8,400 North Carolina students - Read More…

UNC researchers link aging to cellular interactions that occur across generations

UNC researchers link aging to cellular interactions that occur across generations

Shawn Ahmed, PhD, shows that tweaking specific cellular mechanisms helps tiny worms overcome infertility through a pathway of cellular interactions that result in long life. The finding gives clues to how the molecular interactions in cells of one organism affect progeny many generations later.

UNC researchers link aging to cellular interactions that occur across generations - Read More…

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