UNC clinical geneticists Jonathan Berg and James Evans spearhead an ambitious project to catalog all genetic variations implicated in disease.
New test uses PAM50 breast cancer gene signature discovered by UNC’s Perou
Dr. Cynthia Powell of N.C. Children's Hospital and Dr. Jonathan Berg of UNC Lineberger Comprehensive Cancer Center will answer your questions in a live Facebook chat at noon (12 p.m.) Eastern time on Thursday, Sept. 26.
Researchers at UNC plan to sequence the entire genome of 400 infants to determine what useful clinical data can be acquired through the tests.
Key enzymes are found to have a ‘profound effect’ across dozens of genes linked to autism. The insight could help illuminate environmental factors behind autism spectrum disorder and contribute to a unified theory of how the disorder develops.
A genome-wide association analysis led by Dr. Patrick Sullivan of UNC identifies 22 places in the human genome that play a role in development of the mental disorder.
Dr. Patrick Sullivan of UNC is a co-author of the study, which found that schizophrenia and bipolar disorder share the most common genetic variation.
A UNC research team found that genetically engineered mouse models (GEMMs) were able to accurately predict human response to a standard chemotherapy drug combination commonly used in the clinic.
Tarantino, Valdar, and Pardo Manuel de Villena receive five-year R01 from the National Institute for Mental Health
Lisa Tarantino, PhD, assistant professor of psychiatry, and William Valdar, PhD, assistant professor of genetics, are co-principal investigators, and Fernando Pardo Manuel de Villena, PhD, professor of genetics, is co-investigator on a grant entitled, "Role of maternal diet and allelic imbalance in behavior." The grant will fund estimated costs of $3,092,719 over a five-year period.
Clinical geneticist James Evans, MD, PhD helped to open the exhibition, Genome: Unlocking Life's Code. The high-tech, high-intensity display celebrates the 10th anniversary of production of the first complete human genome sequence also known as the genetic blueprint of the human body.
Cynthia Powell, MD, MS, professor of Pediatrics and Genetics, is part of a team of researchers from the University of North Carolina, Duke University, and the University of Michigan that identified the gene, STAC3, for a severe neurological condition that affects some members of the Native American Lumbee tribe in North Carolina.
By better understanding the molecular and biological mechanisms involved with schizophrenia, scientists hope to use this new genetic information to one day develop and design drugs that are more efficacious and have fewer side effects.
Research conducted in fruit flies at the University of North Carolina School of Medicine has pinpointed a specific DNA sequence that both triggers the formation of the “histone locus body” and turns on all the histone genes in the entire block.
Aravind Asokan, PhD, assistant professor of genetics in the School of Medicine, was selected by the American Society of Gene and Cell Therapy to receive a 2013 Outstanding New Investigator Award.
Art of Science Competition sponsored in conjunction with Carolina Biosciences Alumni Reunion and Symposium
Carolina Biosciences Alumni Reunion and Symposium is sponsoring an Art of Science Competition open to all UNC students, staff and faculty. Winners will get to have their art on display at the Ackland Art Museum.
The School of Medicine Office of Graduate Education and the Biological Biomedical Sciences Program are sponsoring a reunion for biosciences graduate alumni from 14 member PhD programs from the School of Medicine, College of Arts and Sciences, School of Pharmacy, and School of Dentistry.
On Feb. 7, the UNC School of Medicine Gene Therapy Center and the Wake Forest Institute for Regenerative Medicine collaborated to host a joint symposium for the first time. Jude Samulski, PhD, professor of pharmacology and director of the UNC Gene Therapy Center and Anthony Atala, MD, chair of the Department of Urology and director of the Wake Forest Institute for Regenerative Medicine served as keynote speakers.
An investigation into diabetes-related outcomes in a rat model, with senior author William Valdar, PhD, assistant professor of genetics at UNC, and first author Leah Solberg Woods, PhD, from the Medical College of Wisconsin, has made the editor's pick in this month's Physiological Genomics, a journal of the American Physiological Society.
William Y. Kim, MD, assistant professor in the departments of medicine and genetics at the University of North Carolina School of Medicine and member of UNC Lineberger Comprehensive Cancer Center, will receive $250,000 during the two-year grant term.
A cutting-edge genomic analysis method has helped researchers track new genetic contributors relevant to diabetes. The results provide a first example that the new tool can help decipher many complex diseases such as obesity and cancer.