UNC geneticists led by Terry Magnuson, PhD, and Ron Chandler, PhD, create the first mouse model of ovarian clear cell carcinoma; show how a known drug can suppress tumor growth.
Postpartum depression (PPD) may have a diverse clinical presentation and this has critical implications for diagnosis, treatment and understanding the underlying biology of the illness, a new study finds.
UNC Lineberger Comprehensive Cancer Center member Jim Evans, MD, PhD, Bryson Distinguished Professor of Genetics and Medicine and director of clinical cancer genetics, has co-authored a commentary in the Journal of the American Medical Association (JAMA) on proposed US Food and Drug Administration (FDA) regulation of genetic testing.
The scientists join 65 UNC colleagues as fellows of the American Association for the Advancement of Science.
UNC researchers and colleagues are the first to develop a mouse model that more accurately reflects human disease symptoms; they found a single gene crucial for disease severity.
UNC’s Dr. Patrick F. Sullivan is one of two researchers nationwide to receive the award.
With his selection to the NIH Council of Councils, Terry Magnuson, PhD, becomes the first UNC scientist appointed to the board dedicated to funding the biggest ideas in medical research.
The work, led by researchers at the UNC Lineberger Comprehensive Cancer Center, UNC-Chapel Hill and other TCGA sites, revamps traditional ideas of how cancers are diagnosed and treated and could also have a profound impact on the future landscape of drug development.
Genes, pathways identified could inform new approaches to treatment
The discovery, from the lab of Brian Strahl, PhD, offers insights for the creation of better, more targeted therapies for various forms of cancer.
‘Science ambassadors’ deploy across the state for annual DNA Day celebration, inspiring students to break stereotypes, ask questions and dream big.
Shawn Ahmed, PhD, shows that tweaking specific cellular mechanisms helps tiny worms overcome infertility through a pathway of cellular interactions that result in long life. The finding gives clues to how the molecular interactions in cells of one organism affect progeny many generations later.
In a new study, researchers from North Carolina State University, UNC-Chapel Hill and other institutions have taken the first steps toward creating a roadmap that may help scientists narrow down the genetic cause of numerous diseases.
Five questions for Chuck Perou, PhD, a UNC geneticist on the hunt for better treatments for the most deadly form of breast cancer
UNC School of Medicine's William Valdar and James Crowley lead a quest to discover the genetic underpinnings of drug side effects.
Eight basic science and clinical departments at UNC finished in the top 10 in their fields.
Two new studies provide further evidence that schizophrenia arises from the combined effects of many genes. Dr. Patrick Sullivan of UNC is a co-author of one of the studies.
The Anorexia Nervosa Genetics Initiative (ANGI) will collect DNA samples from more than 8,000 people with anorexia nervosa (AN) and those without an eating disorder in an effort to detect genes that contribute to this potentially life-threatening illness.
UNC clinical geneticists Jonathan Berg and James Evans spearhead an ambitious project to catalog all genetic variations implicated in disease.
New test uses PAM50 breast cancer gene signature discovered by UNC’s Perou