UNC sequenced the RNA for 10,000 tumor samples as part of The Cancer Genome Atlas project, a National Cancer Institute and National Human Genome Research Institute backed effort to create a comprehensive atlas of the genetic changes in cancer.
A first of its kind study shows that who we inherit genetic variants from – our mother or father – is crucial for the development of diseases and for research studies aimed at finding causes and potential treatments.
Samir Kelada, PhD, assistant professor, Department of Genetics, was one of six scientists across the nation to receive the Outstanding New Environmental Scientist (ONES) award.
UNC researchers led by Karen Mohlke, PhD, and Kari North, PhD, including a consortium of researchers, find 89 new genetic locations that will help scientists pinpoint genes that play roles in different obesity traits.
The current outbreak of the plague in Madagascar shines a light on the need for new approaches to treat the ancient pathogen. A new UNC study unexpectedly unravels a long-held theory on how a fleabite leads to infection.
Scientists from UNC-Chapel Hill have created a new way to investigate epigenetic mechanisms important in diseases ranging from Alzheimer’s to cancers.
The finding has implications for the field of evolutionary genetics and biomedical science, including new ways to research human conditions, such as Down syndrome.
UNC geneticists led by Terry Magnuson, PhD, and Ron Chandler, PhD, create the first mouse model of ovarian clear cell carcinoma; show how a known drug can suppress tumor growth.
Postpartum depression (PPD) may have a diverse clinical presentation and this has critical implications for diagnosis, treatment and understanding the underlying biology of the illness, a new study finds.
UNC Lineberger Comprehensive Cancer Center member Jim Evans, MD, PhD, Bryson Distinguished Professor of Genetics and Medicine and director of clinical cancer genetics, has co-authored a commentary in the Journal of the American Medical Association (JAMA) on proposed US Food and Drug Administration (FDA) regulation of genetic testing.
The scientists join 65 UNC colleagues as fellows of the American Association for the Advancement of Science.
UNC researchers and colleagues are the first to develop a mouse model that more accurately reflects human disease symptoms; they found a single gene crucial for disease severity.
UNC’s Dr. Patrick F. Sullivan is one of two researchers nationwide to receive the award.
With his selection to the NIH Council of Councils, Terry Magnuson, PhD, becomes the first UNC scientist appointed to the board dedicated to funding the biggest ideas in medical research.
The work, led by researchers at the UNC Lineberger Comprehensive Cancer Center, UNC-Chapel Hill and other TCGA sites, revamps traditional ideas of how cancers are diagnosed and treated and could also have a profound impact on the future landscape of drug development.
Genes, pathways identified could inform new approaches to treatment
The discovery, from the lab of Brian Strahl, PhD, offers insights for the creation of better, more targeted therapies for various forms of cancer.
‘Science ambassadors’ deploy across the state for annual DNA Day celebration, inspiring students to break stereotypes, ask questions and dream big.
Shawn Ahmed, PhD, shows that tweaking specific cellular mechanisms helps tiny worms overcome infertility through a pathway of cellular interactions that result in long life. The finding gives clues to how the molecular interactions in cells of one organism affect progeny many generations later.
In a new study, researchers from North Carolina State University, UNC-Chapel Hill and other institutions have taken the first steps toward creating a roadmap that may help scientists narrow down the genetic cause of numerous diseases.