Genetics

The latest genetics news from UNC Health Care and the UNC School of Medicine.

New School of Medicine Program Highlights Precision Medicine at UNC

New School of Medicine Program Highlights Precision Medicine at UNC

The Program for Precision Medicine in Health Care will be led by the UNC School of Medicine’s Jonathan Berg, MD, PhD. The program, funded by a $10-million grant from UNC Health Care, will be a collaboration among multiple departments within the school to bring together existing precision medicine treatments and support future endeavors in this field.

New School of Medicine Program Highlights Precision Medicine at UNC - Read More…

Anti-inflammatory Protein Promotes Healthy Gut Bacteria to Curb Obesity

Anti-inflammatory Protein Promotes Healthy Gut Bacteria to Curb Obesity

UNC School of Medicine researchers led by Jenny Ting, PhD, and colleagues, publish a new approach to weight loss and diabetes prevention.

Anti-inflammatory Protein Promotes Healthy Gut Bacteria to Curb Obesity - Read More…

Genomic study finds a new role for microRNAs as predictors of Crohn’s disease progression

Genomic study finds a new role for microRNAs as predictors of Crohn’s disease progression

These findings by UNC School of Medicine researchers are an important step forward in designing more effective clinical trials and developing personalized Crohn’s disease therapies.

Genomic study finds a new role for microRNAs as predictors of Crohn’s disease progression - Read More…

Preliminary Data from Groundbreaking Genome Editing Clinical Trial Encouraging

Preliminary Data from Groundbreaking Genome Editing Clinical Trial Encouraging

As part of the phase 1 clinical trial for patients with Hunter syndrome, Joseph Muenzer, MD, PhD, performed the UNC Clinical Translational and Research Center's first-ever in vivo genome editing therapy, achieving a milestone in his own career.

Preliminary Data from Groundbreaking Genome Editing Clinical Trial Encouraging - Read More…

Children's Research Institute Seminar Series: "Cross-blood-brain-barrier Gene Delivery for Treating Neuropathic Lysosomal Storage Diseases"

The Children’s Research Institute Seminar Series presents its September speaker, Haiyan Fu, PhD, for her talk, "Cross-blood-brain-barrier Gene Delivery for Treating Neuropathic Lysosomal Storage Diseases."

Children's Research Institute Seminar Series: "Cross-blood-brain-barrier Gene Delivery for Treating Neuropathic Lysosomal Storage Diseases" - Read More…

McKay receives NIH "Maximizing Investigators' Research Award"

McKay receives NIH "Maximizing Investigators' Research Award"

Daniel J. McKay, PhD, assistant professor, Biology and Genetics and Integrative Program for Biological and Genome Studies (iBGS), has received a 5-year $1.25 million MIRA grant for his project titled “Genetic and Epigenetic Mechanisms of Developmental Gene Regulation."

McKay receives NIH "Maximizing Investigators' Research Award" - Read More…

 Researchers find potential key to unlocking the immune system in pancreatic cancer

Researchers find potential key to unlocking the immune system in pancreatic cancer

In the journal Cancer Immunology Research, scientists led by UNC Lineberger's Yuliya Pylayeva-Gupta, PhD, revealed that a molecule called interleukin-35 plays a role in suppressing cancer-fighting immune cells in pancreatic cancer.

Researchers find potential key to unlocking the immune system in pancreatic cancer - Read More…

SOM Office of Research appoints Christopher Gregory director of Office of Research Technologies

SOM Office of Research appoints Christopher Gregory director of Office of Research Technologies

Christopher Gregory, PhD, has been appointed director of the Office of Research Technologies to increase interdisciplinary science and maximize resources available to UNC School of Medicine researchers.

SOM Office of Research appoints Christopher Gregory director of Office of Research Technologies - Read More…

Experts Reaffirm One Gene Associated with Heart Condition, Dispute 20 Previous Gene Associations

Experts Reaffirm One Gene Associated with Heart Condition, Dispute 20 Previous Gene Associations

UNC's Jonathan Berg, MD, PhD, associate professor of genetics and medicine, served on the ClinGen panel to evaluate the validity of genes reported to be associated with Brugada Syndrome, a serious genetic heart arrhythmia condition.

Experts Reaffirm One Gene Associated with Heart Condition, Dispute 20 Previous Gene Associations - Read More…

Getting to the Heart of Congenital Cardiac Defects

Getting to the Heart of Congenital Cardiac Defects

UNC researchers led by Frank Conlon, PhD, shed light on how gene defects lead to congenital heart malformations.

Getting to the Heart of Congenital Cardiac Defects - Read More…

New patent on autism genetic test could stall scientific research

New patent on autism genetic test could stall scientific research

Jim Evans, MD, PhD, was quoted in The Scientist on the potential of a North Carolina-based company charging a licensing fee to scientists who want to sequence the gene HOMER1, which has been linked to autism.

New patent on autism genetic test could stall scientific research - Read More…

UNC Biocuration Core teams with Genomet to support collaboration on genetics research

UNC Biocuration Core teams with Genomet to support collaboration on genetics research

In an effort to advance precision medicine, the Biocuration Core at the UNC School of Medicine is using Genomet’s innovative collaboration platform to strengthen user engagement.

UNC Biocuration Core teams with Genomet to support collaboration on genetics research - Read More…

Scientists identify brain cell types underlying schizophrenia

Scientists identify brain cell types underlying schizophrenia

Karolinska Institutet and UNC School of Medicine researchers, including Patrick Sullivan, PhD, have identified four specific types of brain cells associated with schizophrenia. The findings offer a roadmap for the development of new therapies to target the condition.

Scientists identify brain cell types underlying schizophrenia - Read More…

New genomic research on cardiovascular health in rural North Carolina

New genomic research on cardiovascular health in rural North Carolina

Two genomic-based studies from Heart Healthy Lenoir were published in the last month. Heart Healthy Lenoir was a multidisciplinary research project that aimed to reduce cardiovascular disease in Lenoir County, North Carolina by developing new approaches to care, from prevention to treatment. The lead investigator of the Heart Healthy Lenoir genomics study is Jonathan Schisler, PhD, assistant professor in the Department of Pharmacology and McAllister Heart Institute.

New genomic research on cardiovascular health in rural North Carolina - Read More…

Berg quoted in NY Times, WRAL Tech Wire on genetic screening

Berg quoted in NY Times, WRAL Tech Wire on genetic screening

As genetic testing increases in popularity, experts such as Jonathan Berg, MD, PhD, question the usefulness of screening disease risks for the general public until further research establishes best practices.

Berg quoted in NY Times, WRAL Tech Wire on genetic screening - Read More…

Researchers identify 44 genomic variants associated with depression

Researchers identify 44 genomic variants associated with depression

The study, co-led by Patrick Sullivan of UNC and Naomi Wray of the University of Queensland, is the largest genome-wide association study to date of genetic risk factors for major depression.

Researchers identify 44 genomic variants associated with depression - Read More…

Valdar earns MIRA award from NIH for gene mapping

Valdar earns MIRA award from NIH for gene mapping

The National Institute of General Medical Sciences awarded Will Valdar, PhD, $2.95 million over five years to investigate the architecture of complex traits using the Collaborative Cross housed at UNC-Chapel Hill.

Valdar earns MIRA award from NIH for gene mapping - Read More…

 UNC Lineberger researchers help map the cancer genome, generate key insights

UNC Lineberger researchers help map the cancer genome, generate key insights

UNC Lineberger researchers led two major projects to mark the finale of The Cancer Genome Atlas project, which was backed by the National Cancer Institute and National Human Genome Research Institute.

UNC Lineberger researchers help map the cancer genome, generate key insights - Read More…

ASH Announces Partnership with UNC to Curate Genomic Data for Blood Disease Research

ASH Announces Partnership with UNC to Curate Genomic Data for Blood Disease Research

In partnership with UNC School of Medicine researchers led by Jonathan Berg, MD, PhD, the American Society of Hematology is supporting two expert review panels that will analyze the clinical significance of variants and mutations understood to be associated with myeloid malignancies and platelet disorders with the goal of aiding in their interpretation on diagnostic genetic tests.

ASH Announces Partnership with UNC to Curate Genomic Data for Blood Disease Research - Read More…

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