Research

The latest research news from UNC Health Care and the UNC School of Medicine.

Bulik awarded Distinguished Investigator Grant by Brain & Behavior Research Foundation

Bulik awarded Distinguished Investigator Grant by Brain & Behavior Research Foundation

Cynthia M. Bulik, PhD, Distinguished Professor of Eating Disorders and Founding Director of the UNC Center of Excellence for Eating Disorders, is one of 17 scientists awarded a Distinguished Investigator Grant from the Brain & Behavior Research Foundation. Bulik's project, Binge Eating Disorder Genetics Initiative (BEGIN), will focus on the genetics of binge eating disorders.

Bulik awarded Distinguished Investigator Grant by Brain & Behavior Research Foundation - Read More…

UNC Scientists Discover Proteins Keeping Stem Cells in their Undifferentiated State

UNC Scientists Discover Proteins Keeping Stem Cells in their Undifferentiated State

The lab of Jean Cook, PhD, found how a chain of proteins called an MCM complex could enable the fast cell-division that makes some forms of cancer so dangerous.

UNC Scientists Discover Proteins Keeping Stem Cells in their Undifferentiated State - Read More…

Immunotherapy Could Be Beneficial for Relapsed Acute Myeloid Leukemia

Immunotherapy Could Be Beneficial for Relapsed Acute Myeloid Leukemia

Researchers led by UNC Lineberger's Joshua Zeidner, MD, presented preliminary results from an ongoing phase II trial of the checkpoint inhibitor pembrolizumab and chemotherapy for relaposed or refractory acute myeloid leukemia at the 59th American Society of Hematology Annual Meeting in Atlanta.

Immunotherapy Could Be Beneficial for Relapsed Acute Myeloid Leukemia - Read More…

Using Software, Researchers Predict Tumor Markers That Could Be Immune Targets

Using Software, Researchers Predict Tumor Markers That Could Be Immune Targets

UNC Lineberger researchers led by Benjamin Vincent, MD, reported preliminary findings at the 59th ASH Annual Meeting in Atlanta that are an early step in the overall plan to use the software’s predictions to develop immune-based therapies for leukemia.

Using Software, Researchers Predict Tumor Markers That Could Be Immune Targets - Read More…

Biological Factors Don't Completely Explain Racial Disparities for ‘Good Prognosis’ Breast Cancer

Biological Factors Don't Completely Explain Racial Disparities for ‘Good Prognosis’ Breast Cancer

The biological features of patients’ tumors partially explained a racial disparity for women with hormone receptor-positive, HER2-negative breast cancer, but UNC Lineberger researchers led by Katherine Reeder-Hayes, MD, MBA, MSc, said it didn’t explain it completely. The preliminary findings were reported at the 2017 San Antonio Breast Cancer Symposium.

Biological Factors Don't Completely Explain Racial Disparities for ‘Good Prognosis’ Breast Cancer - Read More…

NCI Grant to Help More Cancer Patients Become Tobacco-Free

NCI Grant to Help More Cancer Patients Become Tobacco-Free

A grant from the National Cancer Institute will help expand tobacco cessation programs for cancer patients at the N.C. Cancer Hospital. Adam O. Goldstein, MD, MPH, will lead the effort.

NCI Grant to Help More Cancer Patients Become Tobacco-Free - Read More…

National Clinical Trial Finds Certain Treatments for Blood Clots Not Effective

National Clinical Trial Finds Certain Treatments for Blood Clots Not Effective

Stephan Moll, MD, professor of medicine and member of the UNC Hemophilia and Thrombosis Center, co-authored the results of a large-scale multicenter clinical trial focusing on catheter-directed thrombolysis and its effects.

National Clinical Trial Finds Certain Treatments for Blood Clots Not Effective - Read More…

Scientists Find Potential Weapons for the Battle Against Antibiotic Resistance

Scientists Find Potential Weapons for the Battle Against Antibiotic Resistance

Led by UNC School of Medicine’s Brian Conlon, PhD, research published in PLoS Biology shows how different bacterial strains interact to make each other more or less resistant to antibiotics.

Scientists Find Potential Weapons for the Battle Against Antibiotic Resistance - Read More…

NIH renews grant funding the Bowles Alcohol Research Center

NIH renews grant funding the Bowles Alcohol Research Center

The center, established 20 years ago and led by Fulton Crews, PhD, will receive more than $8.7 million over five years to continue research on the effects of alcohol on the brain.

NIH renews grant funding the Bowles Alcohol Research Center - Read More…

Pairing cancer genomics with cognitive computing highlights potential therapeutic options

Pairing cancer genomics with cognitive computing highlights potential therapeutic options

Study findings suggest that cognitive computing could help physicians to stay abreast of an ever-expanding body of scientific literature as well as highlight potential cancer therapeutic options. UNC Lineberger's William Kim, MD, is the study's corresponding author.

Pairing cancer genomics with cognitive computing highlights potential therapeutic options - Read More…

The Leukemia & Lymphoma Society awards grant to Savoldo for immunotherapy research

The Leukemia & Lymphoma Society awards grant to Savoldo for immunotherapy research

A grant from The Leukemia & Lymphoma Society will help fund clinical research led by UNC Lineberger's Barbara Savoldo, MD, PhD, into an investigational chimeric antigen receptor (CAR) T-cell treatment for acute lymphoblastic leukemia that would include a built-in "safety switch."

The Leukemia & Lymphoma Society awards grant to Savoldo for immunotherapy research - Read More…

New simple test could help cystic fibrosis patients find best treatment

New simple test could help cystic fibrosis patients find best treatment

In a significant step toward personalized medicine for cystic fibrosis, a minimally-invasive technique developed in the lab of Martina Gentzsch, PhD, shows promise as a fast, inexpensive indicator to help more patients access new treatments.

New simple test could help cystic fibrosis patients find best treatment - Read More…

Could this Protein Protect People against Coronary Artery Disease?

Could this Protein Protect People against Coronary Artery Disease?

Research led by UNC’s Jonathan Schisler, PhD, showed much lower levels of the protein CXCL5 in older people with clogged arteries.

Could this Protein Protect People against Coronary Artery Disease? - Read More…

A New Test to Measure the Effectiveness of CF Drugs

A New Test to Measure the Effectiveness of CF Drugs

A new lab model developed by UNC’s Carla Ribeiro, PhD, and colleagues can be used to test new therapeutics for cystic fibrosis.

A New Test to Measure the Effectiveness of CF Drugs - Read More…

Can asthma be controlled with a vitamin supplement?

Can asthma be controlled with a vitamin supplement?

UNC School of Medicine researchers led by Michelle Hernandez, MD, found that asthma patients taking a kind of vitamin E called gamma tocopherol had less inflammation of the airways. The study points to a new way to control asthma’s chronic symptoms.

Can asthma be controlled with a vitamin supplement? - Read More…

Fat Cell Gene Deficiency Promotes Obesity

Fat Cell Gene Deficiency Promotes Obesity

UNC School of Medicine’s Damaris Lorenzo, PhD, and colleagues show how a gene variant can trigger obesity in mice – without them eating more than control mice – and lead to health concerns related to weight gain.

Fat Cell Gene Deficiency Promotes Obesity - Read More…

Researchers use a skin patch, infrared light, and melanin to battle melanoma

Researchers use a skin patch, infrared light, and melanin to battle melanoma

In lab experiments led by Zhen Gu, PhD, UNC and NC State scientists were able to trigger naturally occurring melanin to boost an immune response against skin cancer cells in mice.

Researchers use a skin patch, infrared light, and melanin to battle melanoma - Read More…

Buse leads clinical trial of new diabetes treatment

Buse leads clinical trial of new diabetes treatment

The study is designed to evaluate whether TTP399 is well tolerated when administered as an add-on to insulin therapy and can improve daily glucose profiles and HbA1c in people living with type 1 diabetes.

Buse leads clinical trial of new diabetes treatment - Read More…

Researchers Compile Scientific Evidence Behind “Nine Truths About Eating Disorders” Ahead of National Eating Disorder Conference

Researchers Compile Scientific Evidence Behind “Nine Truths About Eating Disorders” Ahead of National Eating Disorder Conference

To better educate the public and physicians on what is and isn’t true about eating disorders, UNC’s Cynthia Bulik and fellow researchers delved into the science to substantiate the “Nine Truths About Eating Disorders.”

Researchers Compile Scientific Evidence Behind “Nine Truths About Eating Disorders” Ahead of National Eating Disorder Conference - Read More…

Football Position and Length of Play Affect Brain Impact

Football Position and Length of Play Affect Brain Impact

Results from a newly published UNC study co-authored by MD/PhD student Michael Clark showed that non-speed players with a history of recurrent concussion had lower white matter integrity and lower measure of activation during cognitive tasks.

Football Position and Length of Play Affect Brain Impact - Read More…

Share This: