The Patient-Centered Outcomes Research Institute has awarded contracts totaling more than $12 million to Michael Kappelman, Kelli Allen and Donna Evon. The largest of the three awards, to Dr. Kappelman, is a 5-year, $8 million contract to compare the effectiveness of two drug therapies in the treatment of Crohn’s disease in children.
The sixth annual Translational Medicine Symposium was held this week at the Koury Oral Health Sciences Building at UNC. The event features students trained to engage in the clinical side of research
A new study by UNC researchers has found dramatic improvements in the care of patients with cirrhosis and liver failure and recommends improved treatment strategies for patients with cirrhosis and concurrent bacterial infections.
Cystic fibrosis took five of her siblings at a young age. Now, Wanda O’Neal, PhD, is part of a team of UNC researchers searching for reasons why. Their latest work has provided new insights that will help unravel why a sixth sibling with CF is living a productive life as he turns 50.
Using a weak electric current to alter a specific brain activity pattern, UNC School of Medicine researchers increased creativity in healthy adults. Now they’re testing the same experimental protocol to alleviate symptoms in people with depression.
Born in a former frontier town, UNC graduate student Patrick McCarter explores how our cells respond to dangerous changes in their environment.
A UNC Lineberger-led study found that people with higher-risk melanoma containing either BRAF or NRAS gene mutations had lower survival rates.
Using human cancer cell lines, UNC scientists identified various ways that HER2-positive breast cancer tumors resist therapy, and they discovered a potential combination therapy to overcome multiple mechanisms of resistance and kill cancer cells.
UNC sequenced the RNA for 10,000 tumor samples as part of The Cancer Genome Atlas project, a National Cancer Institute and National Human Genome Research Institute backed effort to create a comprehensive atlas of the genetic changes in cancer.
UNC stem cell expert Scott Magness, PhD, and Duke microbiome researcher John Rawls, PhD, are using a $50,000 grant to develop a new technology to study the co-dependent relationship between the human gut and its resident bacteria.
Spencer Smith, PhD, assistant professor of cell biology and physiology and member of the UNC Neuroscience Center, was featured on North Carolina Now, a nightly program on UNC TV.
A new study of newborns with prenatal drug exposure finds cocaine-specific disruptions in a part of the brain circuitry thought to play an important role in arousal regulation.
Two new faculty members have joined the UNC Lineberger Comprehensive Cancer Center to help launch groundbreaking immunotherapy clinical trials that will test an experimental treatment in which patients’ own immune cells are genetically engineered to fight their cancer.
A new study in PLoS Pathogens shows that HIV can infect the brain early on and should be combated as soon as possible with antiretroviral therapy to limit risk of dementia
UNC School of Medicine scientist Scott Magness and collaborators use their newly developed technology to dissect properties of single stem cells. The advancement will allow researchers to study gastrointestinal disorders and cancers like never before.
Graduate student Jon Hagar is uncovering how our immune systems can overreact to infection and trigger a life-threatening condition.
Research showed that bleeding events were drastically decreased in animals with hemophilia B. Using a viral vector to swap out faulty genes proved safe and could be used for the more common hemophilia A.
Dr. Adam Goldstein, who is director of the tobacco intervention programs in the UNC School of Medicine, argues his point in an opinion piece published in the March/April 2015 issue of Annals of Family Medicine.
A new study led by UNC researchers identifies both where in the brain and how a protein in the brain, called Neuropeptide Y or NPY, can act to suppress binge alcohol drinking. These findings suggest that restoring NPY may be useful for treating alcohol use disorders and may also protect some individuals from becoming alcohol dependent.
A study led by a UNC Lineberger Comprehensive Cancer Center researcher has found that, despite a North Carolina law banning their purchase by minors and requiring online vendors to verify customer age, teens can easily buy electronic cigarettes online.