Research

The latest research news from UNC Health Care and the UNC School of Medicine.

Few online e-cigarette vendors block sales to minors, UNC Lineberger study finds

Few online e-cigarette vendors block sales to minors, UNC Lineberger study finds

A study led by a UNC Lineberger Comprehensive Cancer Center researcher has found that, despite a North Carolina law banning their purchase by minors and requiring online vendors to verify customer age, teens can easily buy electronic cigarettes online.

Few online e-cigarette vendors block sales to minors, UNC Lineberger study finds - Read More…

Genetically speaking, mammals are more like their fathers

Genetically speaking, mammals are more like their fathers

A first of its kind study shows that who we inherit genetic variants from – our mother or father – is crucial for the development of diseases and for research studies aimed at finding causes and potential treatments.

Genetically speaking, mammals are more like their fathers - Read More…

Scientists find a key protein that allows Plavix to conquer platelets

Scientists find a key protein that allows Plavix to conquer platelets

The findings could lead to more personalized approaches to controlling platelet activity during heart attacks and other vascular emergencies and diseases. Wolfgang Bergmeier, PhD, professor of biochemistry and biophysics, member of the McAllister Heart Institute at UNC, is senior author of the paper.

Scientists find a key protein that allows Plavix to conquer platelets - Read More…

Researchers pin down genetic pathways linked to CF disease severity

Researchers pin down genetic pathways linked to CF disease severity

New findings from the UNC School of Medicine may shed light on why cystic fibrosis patients with the same genetic mutation can have different disease severity and may react differently to medications

Researchers pin down genetic pathways linked to CF disease severity - Read More…

Patients who smoke want respect from physicians

Patients who smoke want respect from physicians

How can providers best interact with their patients who smoke and support their efforts to become tobacco-free? A new study by researchers from the UNC Department of Family Medicine and the Lineberger Comprehensive Cancer Center represents one of the first efforts to ask this and other critical questions. The study was lead by Jacqueline Halladay, MD, associate professor, Department of Family Medicine.

Patients who smoke want respect from physicians - Read More…

UNC Lineberger-led study builds understanding of hepatitis C virus replication

UNC Lineberger-led study builds understanding of hepatitis C virus replication

Hepatitis C virus infection is a common cause of liver disease and of liver cancer in the United States. Through a new study that explores one aspect of how the virus hijacks host cell machinery to replicate itself, UNC Lineberger Comprehensive Cancer Center researchers have gained insight into the workings of a potential drug target for hepatitis C.

UNC Lineberger-led study builds understanding of hepatitis C virus replication - Read More…

New UNC-Duke collaboration applies Cystic Fibrosis therapies to heart disease

New UNC-Duke collaboration applies Cystic Fibrosis therapies to heart disease

Given sufficient time, many forms of cardiovascular disease turn into heart failure, our nation’s number one killer. Despite intense efforts to discover new heart medications, none of the current therapies have been able to halt its relentless progression. As a result, researchers have begun looking to other diseases for inspiration. Two researchers from Duke and UNC have received a grant to explore the feasibility of re-purposing STFR drugs for the treatment of cardiovascular disease.

New UNC-Duke collaboration applies Cystic Fibrosis therapies to heart disease - Read More…

Largest ever genome-wide study on body fat and BMI strengthen genetic links to obesity

Largest ever genome-wide study on body fat and BMI strengthen genetic links to obesity

UNC researchers led by Karen Mohlke, PhD, and Kari North, PhD, including a consortium of researchers, find 89 new genetic locations that will help scientists pinpoint genes that play roles in different obesity traits.

Largest ever genome-wide study on body fat and BMI strengthen genetic links to obesity - Read More…

Bubonic Bottleneck: UNC scientists overturn dogma on the plague

Bubonic Bottleneck: UNC scientists overturn dogma on the plague

The current outbreak of the plague in Madagascar shines a light on the need for new approaches to treat the ancient pathogen. A new UNC study unexpectedly unravels a long-held theory on how a fleabite leads to infection.

Bubonic Bottleneck: UNC scientists overturn dogma on the plague - Read More…

Epigenetic Breakthrough: A first of its kind tool to study the histone code

Epigenetic Breakthrough: A first of its kind tool to study the histone code

Scientists from UNC-Chapel Hill have created a new way to investigate epigenetic mechanisms important in diseases ranging from Alzheimer’s to cancers.

Epigenetic Breakthrough: A first of its kind tool to study the histone code - Read More…

Another breastfeeding benefit: preparing baby’s belly for solid food

Another breastfeeding benefit: preparing baby’s belly for solid food

A close examination of gut bacteria reveals that exclusively breastfed babies are better equipped for the transition to solids and potentially an early life with fewer stomach woes

Another breastfeeding benefit: preparing baby’s belly for solid food - Read More…

R2d2 beats Mendel: scientists discover a selfish gene that breaks the ‘law of segregation’

R2d2 beats Mendel: scientists discover a selfish gene that breaks the ‘law of segregation’

The finding has implications for the field of evolutionary genetics and biomedical science, including new ways to research human conditions, such as Down syndrome.

R2d2 beats Mendel: scientists discover a selfish gene that breaks the ‘law of segregation’ - Read More…

Potential pancreatic cancer treatment could increase life expectancy

Potential pancreatic cancer treatment could increase life expectancy

Device that drives drugs into solid tumors that are poorly vascularized opens the possibility of life-saving surgeries in cancer patients. James Byrne, PhD, a medical student and member of Joseph DeSimone’s lab, led the research by constructing the device and examining its ability to deliver chemotherapeutic drugs effectively to pancreatic cancer tumors, as well as two types of breast cancer tumors.

Potential pancreatic cancer treatment could increase life expectancy - Read More…

Simple strategies used by parents lead to improvements in one-year-olds at risk for autism spectrum disorder

Simple strategies used by parents lead to improvements in one-year-olds at risk for autism spectrum disorder

Parents using these strategies, known as Adapted Responsive Teaching (ART), reported significant improvements in their child’s sensory responsiveness, communication and socialization.

Simple strategies used by parents lead to improvements in one-year-olds at risk for autism spectrum disorder - Read More…

UNC researcher co-leads effort to map genomic changes in head and neck cancer

UNC researcher co-leads effort to map genomic changes in head and neck cancer

A study co-led by a UNC Lineberger Comprehensive Cancer Center researcher has identified genomic changes in head and neck cancers linked to the sexually transmitted disease HPV -- the latest finding of a collaborative scientific effort designed to map out the genomic changes driving cancer.

UNC researcher co-leads effort to map genomic changes in head and neck cancer - Read More…

New deep-brain imaging reveals separate functions for nearly identical neurons

New deep-brain imaging reveals separate functions for nearly identical neurons

For the first time, UNC neuroscientist Garret Stuber, PhD, imaged activity patterns of individual brain cells in freely moving mice to link specific basic behaviors to particular neurons.

New deep-brain imaging reveals separate functions for nearly identical neurons - Read More…

Systematic Review Series offered at Health Sciences Library

This spring, catch one or all of the Research Hub @ HSL’s six-part series on systematic reviews. The sessions will provide an introduction and walk attendees through topic refinement, power searching, tracking references, study selection and presentation of results.

Systematic Review Series offered at Health Sciences Library - Read More…

Researchers pinpoint two genes that trigger severest form of ovarian cancer

Researchers pinpoint two genes that trigger severest form of ovarian cancer

UNC geneticists led by Terry Magnuson, PhD, and Ron Chandler, PhD, create the first mouse model of ovarian clear cell carcinoma; show how a known drug can suppress tumor growth.

Researchers pinpoint two genes that trigger severest form of ovarian cancer - Read More…

MRIs link impaired brain activity to inability to regulate emotions in autism

MRIs link impaired brain activity to inability to regulate emotions in autism

UNC researchers find that the bigger the differences in brain activity related to emotion regulation, the more severe the autism. Gabriel Dichter, PhD, associate professor of psychiatry and psychology was the paper's senior author.

MRIs link impaired brain activity to inability to regulate emotions in autism - Read More…

Patient older age not an issue in revision cochlear implantation

Patient older age not an issue in revision cochlear implantation

Sometimes patients with coclear implants need to have a second or "revision" implantation surgery because of device failure. A new UNC study finds that adults age 65 and older do just as well in speech perception after revision cochlear implantation as those younger than 65.

Patient older age not an issue in revision cochlear implantation - Read More…

Share This: