Research

The latest research news from UNC Health Care and the UNC School of Medicine.

FDA should be equitable in proposed regulations on reducing nicotine in cigarettes

FDA should be equitable in proposed regulations on reducing nicotine in cigarettes

A commentary led by family medicine researcher M. Justin Byron, PhD, suggests that a recent FDA policy proposal needs to include little cigars, which look and function like cigarettes, to be equitable and most effective.

FDA should be equitable in proposed regulations on reducing nicotine in cigarettes - Read More…

New Counseling Process for Administering Naltrexone in Hospitalized Patients

New Counseling Process for Administering Naltrexone in Hospitalized Patients

UNC hospitalists led by John R. Stephens, MD, published a study that describes the effectiveness of counseling hospitalized patients with alcohol withdrawal, using naltrexone.

New Counseling Process for Administering Naltrexone in Hospitalized Patients - Read More…

Doctor-patient discussions neglect potential harms of lung cancer screening, study finds

Doctor-patient discussions neglect potential harms of lung cancer screening, study finds

UNC Lineberger researchers led by Daniel Reuland, MD, MPH, report in JAMA Internal Medicine that their analysis of 14 audio-recorded office visit discussions between doctors and patients found the quality of the conversation about lung cancer screening was “poor” and discussion of the potential harms of screening was “virtually nonexistent.” In addition, the doctors spent less than a minute, on average, discussing the issue.

Doctor-patient discussions neglect potential harms of lung cancer screening, study finds - Read More…

Review of scientific evidence on effectiveness of fertility awareness-based methods for contraception underscores need for higher quality studies

Review of scientific evidence on effectiveness of fertility awareness-based methods for contraception underscores need for higher quality studies

The systematic review led by UNC’s Rachel Peragallo Urrutia, MD, was published this week in Obstetrics and Gynecology. It reviewed 53 studies of the effectiveness of fertility awareness-based methods and rated the studies for their quality.

Review of scientific evidence on effectiveness of fertility awareness-based methods for contraception underscores need for higher quality studies - Read More…

 Researchers find potential key to unlocking the immune system in pancreatic cancer

Researchers find potential key to unlocking the immune system in pancreatic cancer

In the journal Cancer Immunology Research, scientists led by UNC Lineberger's Yuliya Pylayeva-Gupta, PhD, revealed that a molecule called interleukin-35 plays a role in suppressing cancer-fighting immune cells in pancreatic cancer.

Researchers find potential key to unlocking the immune system in pancreatic cancer - Read More…

Jonas publishes two JAMA Evidence Reports on ECG Cardiac Screenings

Jonas publishes two JAMA Evidence Reports on ECG Cardiac Screenings

Dan Jonas, MD, MPH, associate professor of medicine and deputy director for research at the Cecil G. Sheps Center for Health Services Research, found that using electrocardiography in screening asymptomatic adults for cardiovascular disease may cause more harm than good.

Jonas publishes two JAMA Evidence Reports on ECG Cardiac Screenings - Read More…

Researchers Reveal Hidden Rules of Genetics for How Life on Earth Began

Researchers Reveal Hidden Rules of Genetics for How Life on Earth Began

UNC researcher Charles Carter, PhD, and Peter Wills, PhD, from the University of Aukland, show how genes were first translated into proteins to offer insight into a long-time scientific mystery.

Researchers Reveal Hidden Rules of Genetics for How Life on Earth Began - Read More…

Pecot featured in story about becoming a doctor and researcher

Pecot featured in story about becoming a doctor and researcher

UNC Lineberger oncologist and cancer researcher Chad Pecot, MD, who was diagnosed with cancer at age 20, now works to stop the spread of lung cancer.

Pecot featured in story about becoming a doctor and researcher - Read More…

 Discovery of kidney cancer driver could lead to new treatment strategy

Discovery of kidney cancer driver could lead to new treatment strategy

In a study published in the journal Science, researchers led by UNC Lineberger's Qing Zhang, PhD, suggest that ZHX2 is a potential new therapeutic target for clear cell renal cell carcinoma, which is the most common type of kidney cancer.

Discovery of kidney cancer driver could lead to new treatment strategy - Read More…

These Gummy Bear-Looking Things Will Inherit the Earth

These Gummy Bear-Looking Things Will Inherit the Earth

What can we learn from tardigrades, aka ‘water bears,’ these ultimate survivors? And what might they help us figure out regarding human health and disease?

These Gummy Bear-Looking Things Will Inherit the Earth - Read More…

Researchers find that private insurance pays more for emergency department visits

Researchers find that private insurance pays more for emergency department visits

UNC researchers led by Jonathan Yun, MD, MPH, find that private insurance had the greatest average annual increase in spending for each ED visit between 1996 through 2015.

Researchers find that private insurance pays more for emergency department visits - Read More…

Carolina researchers fight against current Ebola outbreak

Carolina researchers fight against current Ebola outbreak

Research conducted at Carolina is aiding the fight against the deadly Ebola virus outbreak in the Democratic Republic of Congo that has been declared “largely contained” by the World Health Organization.

Carolina researchers fight against current Ebola outbreak - Read More…

By sending tests in the mail, researchers boost colorectal cancer screening

By sending tests in the mail, researchers boost colorectal cancer screening

Alison Brenner, PhD, MPH, and Stephanie Wheeler, PhD, MPH, researchers with UNC Lineberger’s Carolina Cancer Screening Initiative, in collaboration with the Mecklenburg County Health Department in Charlotte, examined the impact of targeted outreach to more than 2,100 people insured by Medicaid who were not up-to-date with colorectal cancer screening.

By sending tests in the mail, researchers boost colorectal cancer screening - Read More…

Research shows blood cultures performed on children with skin infections largely ineffective

Research shows blood cultures performed on children with skin infections largely ineffective

The majority of blood cultures performed on children with common skin and soft tissue infections are unnecessary, according to a new article by co-authors, Eric Zwemer, MD, and John R. Stephens, MD, of the Division of General Pediatrics and Adolescent Medicines.

Research shows blood cultures performed on children with skin infections largely ineffective - Read More…

 Researchers clarify role of mutations in glioblastoma

Researchers clarify role of mutations in glioblastoma

In a preclinical study, researchers led by UNC Lineberger's Ryan Miller, MD, PhD, investigated whether the location of where the mutation occurred within the sequence of the PIK3CA gene affected the mutation’s ability to help drive cancerous growth. They also evaluated whether the location of the mutation would affect the cancer's response to certain treatments.

Researchers clarify role of mutations in glioblastoma - Read More…

Cohen Lab awarded three grants to study rare neurodegenerative diseases

Cohen Lab awarded three grants to study rare neurodegenerative diseases

Todd J. Cohen, PhD, an assistant professor in the Department of Neurology, and his research lab have recently received three separate foundation grants for a total of $460,000 over three years.

Cohen Lab awarded three grants to study rare neurodegenerative diseases - Read More…

Experts Reaffirm One Gene Associated with Heart Condition, Dispute 20 Previous Gene Associations

Experts Reaffirm One Gene Associated with Heart Condition, Dispute 20 Previous Gene Associations

UNC's Jonathan Berg, MD, PhD, associate professor of genetics and medicine, served on the ClinGen panel to evaluate the validity of genes reported to be associated with Brugada Syndrome, a serious genetic heart arrhythmia condition.

Experts Reaffirm One Gene Associated with Heart Condition, Dispute 20 Previous Gene Associations - Read More…

Higher body fat linked to lower breast cancer risk in younger women

Higher body fat linked to lower breast cancer risk in younger women

An analysis co-led led by UNC Lineberger's Hazel B. Nichols, PhD, linked higher body mass index to lower breast cancer risk for younger women, even for women within a normal weight range.

Higher body fat linked to lower breast cancer risk in younger women - Read More…

Weber and Colleagues' Publication Attracts Most Readers and Citations

Weber and Colleagues' Publication Attracts Most Readers and Citations

David J. Weber, MD, MPH, aims to help his peers keep their patients safe by studying infection control. His study entitled “Effectiveness of ultraviolet devices and hydrogen peroxide systems for terminal room decontamination: Focus on clinical trials” was the most read and cited publication in the American Journal of Infection Control in 2017.

Weber and Colleagues' Publication Attracts Most Readers and Citations - Read More…

Parents ranked cancer prevention as No. 1 provider reason for HPV vaccination

Parents ranked cancer prevention as No. 1 provider reason for HPV vaccination

A survey led by UNC Lineberger's Melissa Gilkey, PhD, and collaborators found that parents ranked cancer prevention as the most compelling reason health care providers can give for recommending the human papillomavirus (HPV) vaccine.

Parents ranked cancer prevention as No. 1 provider reason for HPV vaccination - Read More…

Share This: