UNC sequenced the RNA for 10,000 tumor samples as part of The Cancer Genome Atlas project, a National Cancer Institute and National Human Genome Research Institute-backed effort to create a comprehensive atlas of the genetic changes in cancer.
UNC stem cell expert Scott Magness, PhD, and Duke microbiome researcher John Rawls, PhD, are using a $50,000 grant to develop a new technology to study the co-dependent relationship between the human gut and its resident bacteria.
Two new faculty members have joined the UNC Lineberger Comprehensive Cancer Center to help launch groundbreaking immunotherapy clinical trials that will test an experimental treatment in which patients’ own immune cells are genetically engineered to fight their cancer.
A new study in PLoS Pathogens shows that HIV can infect the brain early on and should be combated as soon as possible with antiretroviral therapy to limit risk of dementia
UNC School of Medicine scientist Scott Magness and collaborators use their newly developed technology to dissect properties of single stem cells. The advancement will allow researchers to study gastrointestinal disorders and cancers like never before.
Graduate student Jon Hagar is uncovering how our immune systems can overreact to infection and trigger a life-threatening condition.
Research showed that bleeding events were drastically decreased in animals with hemophilia B. Using a viral vector to swap out faulty genes proved safe and could be used for the more common hemophilia A.
Dr. Adam Goldstein, who is director of the tobacco intervention programs in the UNC School of Medicine, argues his point in an opinion piece published in the March/April 2015 issue of Annals of Family Medicine.
A new study led by UNC researchers identifies both where in the brain and how a protein in the brain, called Neuropeptide Y or NPY, can act to suppress binge alcohol drinking. These findings suggest that restoring NPY may be useful for treating alcohol use disorders and may also protect some individuals from becoming alcohol dependent.
A study led by a UNC Lineberger Comprehensive Cancer Center researcher has found that, despite a North Carolina law banning their purchase by minors and requiring online vendors to verify customer age, teens can easily buy electronic cigarettes online.
A first of its kind study shows that who we inherit genetic variants from – our mother or father – is crucial for the development of diseases and for research studies aimed at finding causes and potential treatments.
The findings could lead to more personalized approaches to controlling platelet activity during heart attacks and other vascular emergencies and diseases. Wolfgang Bergmeier, PhD, professor of biochemistry and biophysics, member of the McAllister Heart Institute at UNC, is senior author of the paper.
New findings from the UNC School of Medicine may shed light on why cystic fibrosis patients with the same genetic mutation can have different disease severity and may react differently to medications
How can providers best interact with their patients who smoke and support their efforts to become tobacco-free? A new study by researchers from the UNC Department of Family Medicine and the Lineberger Comprehensive Cancer Center represents one of the first efforts to ask this and other critical questions. The study was lead by Jacqueline Halladay, MD, associate professor, Department of Family Medicine.
Hepatitis C virus infection is a common cause of liver disease and of liver cancer in the United States. Through a new study that explores one aspect of how the virus hijacks host cell machinery to replicate itself, UNC Lineberger Comprehensive Cancer Center researchers have gained insight into the workings of a potential drug target for hepatitis C.
Given sufficient time, many forms of cardiovascular disease turn into heart failure, our nation’s number one killer. Despite intense efforts to discover new heart medications, none of the current therapies have been able to halt its relentless progression. As a result, researchers have begun looking to other diseases for inspiration. Two researchers from Duke and UNC have received a grant to explore the feasibility of re-purposing STFR drugs for the treatment of cardiovascular disease.
UNC researchers led by Karen Mohlke, PhD, and Kari North, PhD, including a consortium of researchers, find 89 new genetic locations that will help scientists pinpoint genes that play roles in different obesity traits.
The current outbreak of the plague in Madagascar shines a light on the need for new approaches to treat the ancient pathogen. A new UNC study unexpectedly unravels a long-held theory on how a fleabite leads to infection.
Scientists from UNC-Chapel Hill have created a new way to investigate epigenetic mechanisms important in diseases ranging from Alzheimer’s to cancers.