Research

The latest research news from UNC Health Care and the UNC School of Medicine.

Scientists create genomic resource to explore the biological underpinnings of brain disorders

Scientists create genomic resource to explore the biological underpinnings of brain disorders

Published in Science, this research integrates a broad range of genomics data to help find molecular underpinnings of schizophrenia, autism, and other neuropsychiatric conditions. Hyejung Won, PhD, in the department of genetics and UNC Neuroscience Center was co-first author.

Scientists create genomic resource to explore the biological underpinnings of brain disorders - Read More…

Study finds higher risk of breast cancer for women after childbirth

Study finds higher risk of breast cancer for women after childbirth

UNC Lineberger's Hazel Nichols, PhD, and collaborators from the Premenopausal Breast Cancer Collaborative Group identified elevated breast cancer risk after childbirth in women younger than 55.

Study finds higher risk of breast cancer for women after childbirth - Read More…

Clinical Genome Resource (ClinGen) Endorsed by FDA

Clinical Genome Resource (ClinGen) Endorsed by FDA

UNC researchers were instrumental in the FDA recognition of the ClinGen expert curated human genetic data. In a press release, the FDA announced this first formal recognition of a public database of human genetic variants and their relationship to disease.

Clinical Genome Resource (ClinGen) Endorsed by FDA - Read More…

UNC School of Medicine researchers receive $9.96 million U.S. DoD grant

UNC School of Medicine researchers receive $9.96 million U.S. DoD grant

The US Department of Defense tabbed UNC Marsico Lung Institute researchers led by Richard Boucher, MD, and Ilona Jaspers, PhD, to study the adverse effects of inhaling toxic fumes from burn pits in the field.

UNC School of Medicine researchers receive $9.96 million U.S. DoD grant - Read More…

CAR-T immunotherapy, chemotherapy show promise for fighting relapsed blood cancer

CAR-T immunotherapy, chemotherapy show promise for fighting relapsed blood cancer

At the 60th Annual American Society of Hematology Meeting in San Diego, UNC Lineberger's Natalie Grover, MD, presented preliminary results from a clinical study of an investigational cellular immunotherapy for Hodgkin lymphoma and non-Hodgkin lymphoma expressing the CD30 protein marker.

CAR-T immunotherapy, chemotherapy show promise for fighting relapsed blood cancer - Read More…

Infective endocarditis increases more than tenfold in North Carolina

Infective endocarditis increases more than tenfold in North Carolina

The opioid epidemic is reshaping the epidemiology of heart valve infection, according to a new study led by Asher Shranz, MD, published in the Annals of Internal Medicine.

Infective endocarditis increases more than tenfold in North Carolina - Read More…

Novel immunotoxin shows promise in treating pancreatic cancer

Novel immunotoxin shows promise in treating pancreatic cancer

A study led by first-year UNC School of Medicine student Salma El-Behaedi found that a novel immunotoxin, LMB-100, could be effective in the treatment of pancreatic cancer.

Novel immunotoxin shows promise in treating pancreatic cancer - Read More…

UNC researchers awarded $1.3 million to put diabetes discovery into practice across the U.S.

UNC researchers awarded $1.3 million to put diabetes discovery into practice across the U.S.

A landmark UNC School of Medicine study showed that the finger prick blood glucose test is unnecessary for most people with type 2 diabetes, and now researchers Katrina Donahue and Laura Young received a PCORI grant to implement their findings across the country.

UNC researchers awarded $1.3 million to put diabetes discovery into practice across the U.S. - Read More…

UNC-Chapel Hill Rises to Fifth for Federal Research Funding

UNC-Chapel Hill Rises to Fifth for Federal Research Funding

The latest annual R&D survey reinforces Carolina’s position as a top global research university.

UNC-Chapel Hill Rises to Fifth for Federal Research Funding - Read More…

Boyce receives NIH support for innovative Malaria study in Uganda

Boyce receives NIH support for innovative Malaria study in Uganda

Ross Boyce, MD, MSc, a clinical instructor in the division of infectious diseases, has been awarded a nearly $1-million Career Development Award (K23) from the National Institutes of Health to utilize principles from criminology to map mosquito breeding sites in Western Uganda. The project could increase the efficiency of vector control in the region.

Boyce receives NIH support for innovative Malaria study in Uganda - Read More…

Can Genetic Therapy Help Kids with Angelman Syndrome Overcome Seizures?

Can Genetic Therapy Help Kids with Angelman Syndrome Overcome Seizures?

The UNC School of Medicine lab of Ben Philpot, PhD, discovered key details for how a deficiency in the gene UBE3A affects the brain and how replacing it could benefit children with the neuro-genetic disorder.

Can Genetic Therapy Help Kids with Angelman Syndrome Overcome Seizures? - Read More…

 Researchers identify resistance mechanism to possible pancreatic cancer treatment

Researchers identify resistance mechanism to possible pancreatic cancer treatment

In the journal Cancer Cell, UNC Lineberger's Channing Der, PhD, and colleagues describe how pancreatic cancer may develop resistance to ERK inhibitors in pancreatic cancer.

Researchers identify resistance mechanism to possible pancreatic cancer treatment - Read More…

Scientists train a computer to classify breast cancer tumors

Scientists train a computer to classify breast cancer tumors

In a study published in the journal NPJ Breast Cancer, researchers led by Charles Perou, PhD, and Melissa Troester, PhD, reported they used a form of artificial intelligence called machine learning, or deep learning, to train a computer to identify certain features of breast cancer tumors from images.

Scientists train a computer to classify breast cancer tumors - Read More…

UNC Researcher Finds Gender Disparities in Admissions, Treatment for Heart Attack Patients, Earns Nomination for AHA Award

UNC Researcher Finds Gender Disparities in Admissions, Treatment for Heart Attack Patients, Earns Nomination for AHA Award

Sameer Arora, MD, a UNC School of Medicine cardiology fellow, was nominated for the Elizabeth Barrett-Connor Research Award for Young Investigators in Training for his study showing young women are having proportionally more heart attacks than young men.

UNC Researcher Finds Gender Disparities in Admissions, Treatment for Heart Attack Patients, Earns Nomination for AHA Award - Read More…

 By solving a mystery of gene repair, scientists uncover an exception to biology’s rules

By solving a mystery of gene repair, scientists uncover an exception to biology’s rules

UNC Lineberger's Dale Ramsden, PhD, and his colleagues published a major study in the journal Science revealing surprising findings about the way major breaks in our DNA are repaired.

By solving a mystery of gene repair, scientists uncover an exception to biology’s rules - Read More…

Researchers awarded $5.5M to improve colorectal cancer screening in North Carolina

Researchers awarded $5.5M to improve colorectal cancer screening in North Carolina

UNC Lineberger researchers were awarded $5.5 million to increase colorectal cancer screening, follow-up, and care referrals in community health centers in North Carolina. Daniel S. Reuland, MD, MPH, leads UNC Lineberger's Carolina Cancer Screening Initiative.

Researchers awarded $5.5M to improve colorectal cancer screening in North Carolina - Read More…

Can Stimulating the Brain Treat Chronic Pain?

Can Stimulating the Brain Treat Chronic Pain?

Neuroscientists and chronic pain experts at the UNC School of Medicine used a weak alternating current of electricity to target a specific part of the brain and significantly decrease chronic lower back pain in all participants of a small clinical trial.

Can Stimulating the Brain Treat Chronic Pain? - Read More…

Can Scientists Change Mucus to Make It Easier to Clear, Limiting Harm to Lungs?

Can Scientists Change Mucus to Make It Easier to Clear, Limiting Harm to Lungs?

UNC School of Medicine and Duke University researchers, led by Brian Button, PhD, show why coughing can’t force mucus free from airways to help people battle cystic fibrosis and chronic bronchitis, and how new treatments could alter mucus to make coughing more therapeutic.

Can Scientists Change Mucus to Make It Easier to Clear, Limiting Harm to Lungs? - Read More…

Hip fracture study compares hospitalist and non-hospitalist services

Hip fracture study compares hospitalist and non-hospitalist services

A newly-published study led by John R. Stephens, MD, professor of medicine and pediatrics in the division of hospital medicine, compared outcomes for patients with hip fracture managed by hospitalist versus non-hospitalist services. Findings suggest there is a benefit to hospitalist co-management.

Hip fracture study compares hospitalist and non-hospitalist services - Read More…

Nephrology study shows need for more training in women's health

Nephrology study shows need for more training in women's health

Clinical instructor Monica Reynolds, MD, presented research at ASN Kidney Week 2018 that shows nephrologists often lack confidence in managing women's health issues that may be related to kidney disease. The study was selected from thousands for special release during ASN Kidney Week, the premier US and international clinical and scientific meeting focused on kidney disease.

Nephrology study shows need for more training in women's health - Read More…

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