Research

The latest research news from UNC Health Care and the UNC School of Medicine.

Severe burns, injuries from e-cigarette explosions go under-reported across the country

Severe burns, injuries from e-cigarette explosions go under-reported across the country

In a new British Medical Journal editorial, UNC School of Medicine researchers and physicians stress the need for better worldwide surveillance of e-cigarette-related burns and better regulation of e-cigarettes to reduce burn injuries.

Severe burns, injuries from e-cigarette explosions go under-reported across the country - Read More…

Particular HPV strain linked to improved prognosis for throat cancer

Particular HPV strain linked to improved prognosis for throat cancer

In an analysis of survival data for a population of patients with a particular type of head and neck cancer, UNC Lineberger researchers confirmed that a particular strain of HPV, a virus linked to multiple cancers, resulted in better overall survival for patients with oropharyngeal cancer than patients with other strains of the virus.

Particular HPV strain linked to improved prognosis for throat cancer - Read More…

UNC receives $18 million to develop mobile technology to prevent and treat HIV in adolescents

UNC receives $18 million to develop mobile technology to prevent and treat HIV in adolescents

iTech project will target people under the age of 30, the population with most new HIV infections in US. The effort is led by Lisa Hightow-Weidman, MD, MPH, associate professor of medicine.

UNC receives $18 million to develop mobile technology to prevent and treat HIV in adolescents - Read More…

Closing the Diversity Gap

Closing the Diversity Gap

UNC researchers publish special report exploring the reasons why PhD-trained scientists choose careers in or out of academia.

Closing the Diversity Gap - Read More…

UNC awarded high-profile NIH grant to research environmental influences on child health

UNC awarded high-profile NIH grant to research environmental influences on child health

UNC School of Medicine’s Michael O’Shea, MD, is the principal investigator for the $5-million grant to analyze data and follow children over time to study the origins of diseases and conditions.

UNC awarded high-profile NIH grant to research environmental influences on child health - Read More…

Baby teeth and autism: UNC part of large NIH study of environmental risk factors

Baby teeth and autism: UNC part of large NIH study of environmental risk factors

Autism researchers will use new technology to study baby teeth of children who have siblings with autism to learn if siblings are more likely to develop the disorder if exposed to chemicals while in the womb.

Baby teeth and autism: UNC part of large NIH study of environmental risk factors - Read More…

Tar Heels go viral: UNC researchers featured on “This Week in Virology” podcast

Tar Heels go viral: UNC researchers featured on “This Week in Virology” podcast

Virologists with the UNC School of Medicine participated in last week's on-campus recording of a popular virology podcast.

Tar Heels go viral: UNC researchers featured on “This Week in Virology” podcast - Read More…

Racial gaps persist in how breast cancer survivors function, feel during treatment and after

Racial gaps persist in how breast cancer survivors function, feel during treatment and after

A UNC Lineberger study published in the journal Breast Cancer Research and Treatment drew upon surveys that assessed health-related quality of life issues for women aged 20 to 74 years who lived in North Carolina and had breast cancer. The analysis was part of the third phase of the Carolina Breast Cancer Study.

Racial gaps persist in how breast cancer survivors function, feel during treatment and after - Read More…

Scientists discover interplay of yin-yang antagonists vital for cell division

Scientists discover interplay of yin-yang antagonists vital for cell division

Although mutated versions of the protein Cdh1 have not been found in cancers, the protein’s degradation at a key moment during the cell cycle may spur on cancerous cell division.

Scientists discover interplay of yin-yang antagonists vital for cell division - Read More…

UNC researchers identify how hepatitis A virus causes liver injury

UNC researchers identify how hepatitis A virus causes liver injury

A new report in the journal Science describes how the virus can jump species, including to mice – a finding that has major implications for researching the disease and host immune responses to the virus. Jason Whitmire, PhD, and Stanley Lemon, MD, led the research team.

UNC researchers identify how hepatitis A virus causes liver injury - Read More…

UNC Hospitals’ quality improvement program leads to quicker treatment of STEMI heart attacks

UNC Hospitals’ quality improvement program leads to quicker treatment of STEMI heart attacks

To address full cardiac arrest of hospital patients, new measures reduced the average time between symptom onset and the start of treatment by 72 percent.

UNC Hospitals’ quality improvement program leads to quicker treatment of STEMI heart attacks - Read More…

An Epigenetic First: researchers pinpoint protein's role in key biological process

An Epigenetic First: researchers pinpoint protein's role in key biological process

UNC researchers help piece together how the key players in DNA methylation work together during gene regulation, a key finding needed to develop better therapies.

An Epigenetic First: researchers pinpoint protein's role in key biological process - Read More…

UNC and Minnesota researchers earn NIH grant to explore infant brain development

UNC and Minnesota researchers earn NIH grant to explore infant brain development

Collaboration between the UNC School of Medicine and the University of Minnesota aims to provide scientists with breakthrough information about how the human brain develops from birth through early childhood.

UNC and Minnesota researchers earn NIH grant to explore infant brain development - Read More…

Biology discovery: tight DNA packaging protects against ‘jumping genes,’ potential cellular destruction

Biology discovery: tight DNA packaging protects against ‘jumping genes,’ potential cellular destruction

UNC study indicates that the “heterochromatin” form of DNA packaging mainly guards against virus-like genetic elements that destroy genes and destabilize the genome, a precursor of disease.

Biology discovery: tight DNA packaging protects against ‘jumping genes,’ potential cellular destruction - Read More…

UNC-Chapel Hill and Duke Team Up to Reduce Tobacco Use

UNC-Chapel Hill and Duke Team Up to Reduce Tobacco Use

Duke University and the University of North Carolina at Chapel Hill Schools of Medicine and Cancer Hospitals, with support from the North Carolina Area Health Education Centers Program, are collaborating on an innovative training program to prepare health care providers across North Carolina and the U.S. to better assist people addicted to tobacco products and help them become “tobacco free.”

UNC-Chapel Hill and Duke Team Up to Reduce Tobacco Use - Read More…

Study finds links between physicians setting cancer care guidelines and drug industry

Study finds links between physicians setting cancer care guidelines and drug industry

UNC Lineberger researchers, led by Aaron Mitchell, MD, found a high prevalence of financial relationships among authors who helped develop a leading set of cancer care guidelines in the United States in a study published in JAMA Oncology. They say the work lays the foundation for future studies of whether the payments influenced clinical practice or guideline recommendations.

Study finds links between physicians setting cancer care guidelines and drug industry - Read More…

Researchers question process for reviewing coverage of ‘off label’ cancer drug use

Researchers question process for reviewing coverage of ‘off label’ cancer drug use

In a paper published online by the Journal of the American Medical Association, UNC Lineberger physician-researchers led by Ethan Basch, MD, MSc, raised concerns that there are inconsistencies between the five reference guides, or compendia, that the Centers for Medicare and Medicaid Services uses to determine which drugs it will reimburse for off-label uses in cancer care.

Researchers question process for reviewing coverage of ‘off label’ cancer drug use - Read More…

UNC PREP reports impressive results

UNC PREP reports impressive results

Newly released research shows that the UNC Postbaccalaureate Research Education Program (PREP) is setting a high standard for the other 31 NIH-funded PREP programs across the country.

UNC PREP reports impressive results - Read More…

UNC and Duke collaborations score big wins in biomedical research

UNC and Duke collaborations score big wins in biomedical research

Pilot funding catalyzes progress on gene editing tools and algorithms to better predict pediatric drug safety.

UNC and Duke collaborations score big wins in biomedical research - Read More…

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