Research

The latest research news from UNC Health Care and the UNC School of Medicine.

Risk of death for adults with blood cancer higher in three N.C. regions

Risk of death for adults with blood cancer higher in three N.C. regions

UNC Lineberger researchers led by Dr. William A. Wood found that for patients treated in a hospital, the risk of death from acute myeloid leukemia was elevated in three regions of the state compared to a benchmark.

Risk of death for adults with blood cancer higher in three N.C. regions - Read More…

Researchers discover how faulty genetic instructions drive a deadly blood cancer in adults

Researchers discover how faulty genetic instructions drive a deadly blood cancer in adults

A study by UNC Lineberger researcher G. Greg Wang, PhD, and colleagues uncovered the genetic mechanism for how acute myeloid leukemia cells with a specific DNA mutation stay as undifferentiated cells, rather than maturing into healthy blood cells.

Researchers discover how faulty genetic instructions drive a deadly blood cancer in adults - Read More…

Duronio named Associate Dean for Research

Duronio named Associate Dean for Research

Bob Duronio, PhD, has been named Associate Dean for Research at the UNC School of Medicine. Duronio is a professor of biology in the College of Arts and Sciences and a professor of genetics in the School of Medicine. He is also a member of the UNC Lineberger Comprehensive Cancer Center and directs the Integrative Program for Biological and Genome Sciences.

Duronio named Associate Dean for Research - Read More…

Binge-eating disorder patients respond well to major forms of treatment

Binge-eating disorder patients respond well to major forms of treatment

Psychological and medication treatment options are available to help patients with binge-eating disorder (BED) to achieve abstinence and improve other symptoms.

Binge-eating disorder patients respond well to major forms of treatment - Read More…

New ImPACT initiative puts graduate students on the path toward successful science careers

New ImPACT initiative puts graduate students on the path toward successful science careers

The immersion internship program pairs young scientists with leading companies and organizations throughout the Triangle to bolster experience outside academia.

New ImPACT initiative puts graduate students on the path toward successful science careers - Read More…

UNC researchers help create key diagnostic measures for gastrointestinal disorders

UNC researchers help create key diagnostic measures for gastrointestinal disorders

UNC School of Medicine faculty members took on critical roles in amending diagnostic criteria questionnaires for functional GI disorders, which affect millions of people worldwide.

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UNC a lead site in clinical trial of three hepatitis C medications

UNC a lead site in clinical trial of three hepatitis C medications

Dr. Michael Fried, director of the UNC Liver Center, is a co-principal investigator of the PRIORITIZE Study.

UNC a lead site in clinical trial of three hepatitis C medications - Read More…

E-cigarette use can alter hundreds of genes involved in airway immune defense

E-cigarette use can alter hundreds of genes involved in airway immune defense

The long-term health effects of e-cigarettes remain unknown, but toxicologists at UNC are now uncovering how use of e-cigarettes affect genes involved in upper airway immune defense.

E-cigarette use can alter hundreds of genes involved in airway immune defense - Read More…

The re-programmer: Qian receives global award for stem cell research

The re-programmer: Qian receives global award for stem cell research

Qian’s award-winning research explores cellular reprogramming in cardiac regeneration and disease modeling.

The re-programmer: Qian receives global award for stem cell research - Read More…

Diabetes drug lowers risk of cardiovascular complications, kidney disease

Diabetes drug lowers risk of cardiovascular complications, kidney disease

For the first time, a large clinical trial showed across-the-board cardiovascular benefit of a diabetes drug – liraglutide – a much-needed outcome for people with type 2 diabetes.

Diabetes drug lowers risk of cardiovascular complications, kidney disease - Read More…

UNC researchers awarded pilot grants for Zika research

UNC researchers awarded pilot grants for Zika research

UNC investigators will study diagnostics, transmission, and neurological effects of Zika, which has been reported in 62 countries and territories.

UNC researchers awarded pilot grants for Zika research - Read More…

Reuland, Brenner lead study published in AJPM

Alison Brenner, PhD, MPH, deputy director of research for the Decision Support Lab at the Cecil G Sheps Center for Health Services, was first author and Dan Reuland, MD, MPH, a UNC Lineberger member and professor in the UNC School of Medicine, was senior author of a paper published in the American Journal of Preventive Medicine. Multiple other UNC researchers were collaborators on the study, called "Colorectal Cancer Screening in Vulnerable Patients."

Reuland, Brenner lead study published in AJPM - Read More…

The Bigger the Bottle, the Bigger the Baby?

The Bigger the Bottle, the Bigger the Baby?

A new UNC School of Medicine study shows that the size of a bottle may contribute to greater weight gain and size for formula-fed infants, putting them at greater risk for obesity later in life.

The Bigger the Bottle, the Bigger the Baby? - Read More…

Cancer patients miss appointments, prescriptions due to inability to afford care

Cancer patients miss appointments, prescriptions due to inability to afford care

More than one-in-four cancer patients had to pay more for medical care than they could afford, according to a study led by UNC Lineberger member Stacie Dusetzina, PhD. A reported 18 percent were unable to afford their prescription medications.

Cancer patients miss appointments, prescriptions due to inability to afford care - Read More…

Bacteria found in female upper reproductive tract, once thought sterile

Bacteria found in female upper reproductive tract, once thought sterile

In a preliminary finding (abstract 5568) presented at the 2016 American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago, UNC Lineberger researchers Wendy Brewster, MD, PhD and Temitope Keku, PhD revealed they have found bacteria in the ovaries and fallopian tubes. Researchers also uncovered a trend toward a distinct bacterial profile in women with ovarian cancer.

Bacteria found in female upper reproductive tract, once thought sterile - Read More…

Advanced cancer patients receive aggressive care at high rates at the end of life

Advanced cancer patients receive aggressive care at high rates at the end of life

A national health claims analysis of cancer patients who were younger than age 65 and had metastatic disease revealed that nearly two-thirds were admitted to the hospital or visited the emergency room in the last 30 days of their lives. The UNC Lineberger researchers who led the study also found that nearly a third of patients died in the hospital.

Advanced cancer patients receive aggressive care at high rates at the end of life - Read More…

Duke/UNC Team Testing New Strategies to Prevent Clotting in Patients with Pancreatic Cancer

Duke/UNC Team Testing New Strategies to Prevent Clotting in Patients with Pancreatic Cancer

CTSA collaborative funding award supports mouse-model research. Nigel Mackman, PhD, of UNC, and Rebekah White, MD, of Duke are leading the effort.

Duke/UNC Team Testing New Strategies to Prevent Clotting in Patients with Pancreatic Cancer - Read More…

Patient Centered Outcomes Research Institute awards funding to address research priorities in health care for women with diabetes

Patient Centered Outcomes Research Institute awards funding to address research priorities in health care for women with diabetes

Wanda Nicholson, MD, MPH, MBA, director of the Diabetes and Obesity Core at the UNC Center for Women’s Health Research and member of the UNC Diabetes Center, will partner with Wendy Bennett, MD, MPH, of Johns Hopkins University, to create an online network to engage women with diabetes.

Patient Centered Outcomes Research Institute awards funding to address research priorities in health care for women with diabetes - Read More…

In all U.S. regions, broad support for increasing legal age of tobacco sales

In all U.S. regions, broad support for increasing legal age of tobacco sales

Researchers from the University of North Carolina at Chapel Hill and East Carolina University report in the American Journal of Preventive Medicine that in all nine regions of the country, a majority of adults supported increasing the minimum legal age for tobacco product sales. They also found the most support for increasing the minimum age to 21 rather than to 20 or 19.

In all U.S. regions, broad support for increasing legal age of tobacco sales - Read More…

Sancar earns UNC Board of Governors’ highest faculty honor

Sancar earns UNC Board of Governors’ highest faculty honor

Winning the Gardner Award is the latest in a long line of international achievements for Sancar, who shared the 2015 Nobel Prize in Chemistry for his groundbreaking work on DNA repair.

Sancar earns UNC Board of Governors’ highest faculty honor - Read More…

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