Research

The latest research news from UNC Health Care and the UNC School of Medicine.

Scientists elucidate genetic underpinnings of congenital heart disease

Scientists elucidate genetic underpinnings of congenital heart disease

Led by scientists at the UNC School of Medicine, the five-year multi-lab effort lays the groundwork for developing treatments.

Scientists elucidate genetic underpinnings of congenital heart disease - Read More…

UNC autism article named one of top 10 papers of 2015

UNC autism article named one of top 10 papers of 2015

Researchers at the Carolina Institute for Developmental Disabilities tracking age-related issues of autism identified an increased risk of Parkinson’s disease in this high-impact paper.

UNC autism article named one of top 10 papers of 2015 - Read More…

Loeser demonstrates new mechanism for how reactive oxygen species contribute to arthritis

Loeser demonstrates new mechanism for how reactive oxygen species contribute to arthritis

Richard Loeser, MD, takes a new look at the role of reactive oxygen species or "free radicals" in arthritis, and provides data needed to design new therapies for this debilitating disease.

Loeser demonstrates new mechanism for how reactive oxygen species contribute to arthritis - Read More…

Study finds no link between subcortical brain volumes and genetic risk for schizophrenia

Study finds no link between subcortical brain volumes and genetic risk for schizophrenia

Proof-of-concept study provides roadmap for future research into possible associations between brain volume measures and known genetic risk factors.

Study finds no link between subcortical brain volumes and genetic risk for schizophrenia - Read More…

New gene therapy treatment proves effective for rare blood disorder

New gene therapy treatment proves effective for rare blood disorder

Researchers at the University of North Carolina and The Children’s Hospital of Philadelphia treated factor VII deficient dogs with normal copies of genes; three years later the dogs remain healthy with no side effects.

New gene therapy treatment proves effective for rare blood disorder - Read More…

UNC approved for a $248,594 award from Patient-Centered Outcomes Research Institute

UNC approved for a $248,594 award from Patient-Centered Outcomes Research Institute

The goal of the award is to bring mothers and providers together to address unmet health care needs during the “fourth trimester.”

UNC approved for a $248,594 award from Patient-Centered Outcomes Research Institute - Read More…

Zylka and Philpot to lead UNC Neuroscience Center

Zylka and Philpot to lead UNC Neuroscience Center

The research collaborators, who have made scientific breakthroughs in the fields of chronic pain, autism, and Angelman syndrome, will serve as director and associate director, replacing longtime director William Snider.

Zylka and Philpot to lead UNC Neuroscience Center - Read More…

Researchers further illuminate pathway for treatment of cystic fibrosis

Researchers further illuminate pathway for treatment of cystic fibrosis

New research findings from the UNC School of Medicine add further clarity to a question that has polarized the cystic fibrosis research community.

Researchers further illuminate pathway for treatment of cystic fibrosis - Read More…

Study finds gaps in patient knowledge of breast reconstruction surgery and complications

Study finds gaps in patient knowledge of breast reconstruction surgery and complications

In a study published in the journal Annals of Surgery, researchers report that breast cancer patients surveyed about their knowledge of breast reconstruction were only moderately informed about the procedure, and their knowledge of complications was low.

Study finds gaps in patient knowledge of breast reconstruction surgery and complications - Read More…

UNC Lineberger researchers identify DNA repair enzyme as a potential brain cancer drug target

UNC Lineberger researchers identify DNA repair enzyme as a potential brain cancer drug target

In the journal Cell Reports, UNC Lineberger researchers report that when they removed Dicer from preclinical models of medulloblastoma, a common type of brain cancer in children, they found high levels of DNA damage in the cancer cells, leading to the cells’ death.

UNC Lineberger researchers identify DNA repair enzyme as a potential brain cancer drug target - Read More…

UNC/Duke Team Publish on Using CRISPR Technique on Adult Mammals

UNC/Duke Team Publish on Using CRISPR Technique on Adult Mammals

A team of investigators supported in part by a $50,000 CTSA-supported UNC /Duke Collaborative Pilot Program has published results of their research into using CRISPR to treat an adult mouse model of Duchenne muscular dystrophy using a virus to deliver the gene-editing system. This marks the first time that the CRISPR technique has successfully treated a genetic disease inside a fully developed living mammal with a strategy that has the potential to be translated to human therapy.

UNC/Duke Team Publish on Using CRISPR Technique on Adult Mammals - Read More…

Female Urologists Still Earn Less Money Than Their Male Counterparts

Female Urologists Still Earn Less Money Than Their Male Counterparts

Despite Gender Disparity in Compensation, Increasing Number of Women Entering the Field, According to New Study Published in The Journal of Urology®

Female Urologists Still Earn Less Money Than Their Male Counterparts - Read More…

Study opens new door for ALS drug discovery

Study opens new door for ALS drug discovery

For the first time, scientists pin down the structure of toxic clumps of a protein associated with a large number of ALS cases, opening new avenues in the pursuit of drugs to stem the disease.

Study opens new door for ALS drug discovery - Read More…

The Power of Proteins

The Power of Proteins

Biomedical engineering student Scott Vu creates a new tool that prompts bacteria to make proteins for various biotech industrial uses.

The Power of Proteins - Read More…

Discovery shows how herpes simplex virus reactivates in neurons to trigger disease

Discovery shows how herpes simplex virus reactivates in neurons to trigger disease

About 90 percent of us live with HSV inside brain cells. Under stress, the virus leaves neurons and can cause cold sores, recurrent eye infection, and in rare cases encephalitis.

Discovery shows how herpes simplex virus reactivates in neurons to trigger disease - Read More…

The Man Behind the Nobel Prize

The Man Behind the Nobel Prize

This week, Aziz Sancar is in Sweden to accept the Nobel Prize in Chemistry. Life since the announcement that he won has been a little hectic.

The Man Behind the Nobel Prize - Read More…

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