Research

The latest research news from UNC Health Care and the UNC School of Medicine.

Hu Earns NSF Early Career Award

Hu Earns NSF Early Career Award

Xiaogang Hu, PhD, in the UNC/NCSU Joint Department of Biomedical Engineering, was selected to receive a National Science Foundation Early Career Award to enhance the quality of biomedical technology addressing neurological conditions.

Hu Earns NSF Early Career Award - Read More…

NIH awards nearly $2 million to Cell Microsystems to boost biomedical research

NIH awards nearly $2 million to Cell Microsystems to boost biomedical research

The UNC School of Medicine lab of William Marzluff, PhD, will collaborate with Cell Microsystems on gene editing projects to speed up the use of CRISPR workflows in lab experiments.

NIH awards nearly $2 million to Cell Microsystems to boost biomedical research - Read More…

Researchers Find Fewer Hospital and Nursing Home Admissions, and a 16 Percent Drop in Medical Expenses, Among Recipients of Medically Tailored Meals

Researchers Find Fewer Hospital and Nursing Home Admissions, and a 16 Percent Drop in Medical Expenses, Among Recipients of Medically Tailored Meals

The study, led by UNC's Seth A. Berkowitz, MD, MPH, assistant professor of general medicine and clinical epidemiology, found that participation in a medically tailored meals program was associated with fewer hospital admissions and nursing home admissions, and less overall medical spending.

Researchers Find Fewer Hospital and Nursing Home Admissions, and a 16 Percent Drop in Medical Expenses, Among Recipients of Medically Tailored Meals - Read More…

Researchers study strategies for using nanotechnology to boost cancer therapeutics

Researchers study strategies for using nanotechnology to boost cancer therapeutics

Four UNC Lineberger researchers – Leaf Huang, Alexander Kabanov, Andrew Wang, and Jenny Ting – presented strategies for using tiny particles to boost cancer treatment as part of a National Cancer Institute site visit.

Researchers study strategies for using nanotechnology to boost cancer therapeutics - Read More…

NCI awards $2.2M to Pylayeva-Gupta to investigate immune responses in pancreatic cancer

NCI awards $2.2M to Pylayeva-Gupta to investigate immune responses in pancreatic cancer

The National Cancer Institute has awarded a five-year grant of more than $2.2 million to UNC Lineberger’s Yuliya Pylayeva-Gupta, PhD, to support her research into the immune response in pancreatic cancer, one of the deadliest cancers.

NCI awards $2.2M to Pylayeva-Gupta to investigate immune responses in pancreatic cancer - Read More…

New details revealed to explain how tumors recruit blood vessels

New details revealed to explain how tumors recruit blood vessels

A study by UNC Lineberger researchers Chad Pecot, MD, and Salma Azam helps explain how tumors recruit blood vessels that provide fuel for their growth as well as an avenue for the tumors to spread.

New details revealed to explain how tumors recruit blood vessels - Read More…

Researchers Identify How Liver Cells Protect Against Viral Attacks

Researchers in Chapel Hill and Tokyo have discovered a mechanism by which liver cells' intrinsic resistance to diverse RNA viruses is regulated. This work, co-authored by UNC's Stanley Lemon, MD, has implications for cellular responses to hepatitis, dengue and Zika.

Researchers Identify How Liver Cells Protect Against Viral Attacks - Read More…

U.S. and Malawian partners implement malaria vaccine for children in Africa

U.S. and Malawian partners implement malaria vaccine for children in Africa

The world’s first vaccine for malaria will be tested in a pilot study beginning this April in three countries with a high burden of the disease among children, according to researchers leading the project from the UNC School of Medicine and UNC Project-Malawi. A previous study found the vaccine RTS,S/AS01 provides partial protection against malaria in young children. In Malawi, malaria is the main cause of illness and death among children age 5 and younger.

U.S. and Malawian partners implement malaria vaccine for children in Africa - Read More…

2019 Marks UNC’s Third Year Participating in Largest Genetic Autism Research Study

2019 Marks UNC’s Third Year Participating in Largest Genetic Autism Research Study

Gabriel Dichter, PhD, director of research at the Carolina Institute for Developmental Disabilities, said one of the main goals of the SPARK project is to help determine the genes that cause autism.

2019 Marks UNC’s Third Year Participating in Largest Genetic Autism Research Study - Read More…

Fischer and Wohl Author NEJM Perspective About Ebola Care

Fischer and Wohl Author NEJM Perspective About Ebola Care

UNC's William A. Fischer II, MD, and David A. Wohl, MD, are part of an international group of authors that contributed to a Perspective piece published in the New England Journal of Medicine. The piece argues that patients with Ebola virus disease in countries with limited resources should be treated according to the same standard of care used in countries where resources are more readily available.

Fischer and Wohl Author NEJM Perspective About Ebola Care - Read More…

Studies explore mechanisms behind obesity-cancer link

Studies explore mechanisms behind obesity-cancer link

New studies led by University of North Carolina Lineberger Comprehensive Cancer Center researchers explore biological mechanisms behind obesity and its link with cancer.

Studies explore mechanisms behind obesity-cancer link - Read More…

New grant allows Vora to collaborate with Duke to identify novel genes critical to human brain development

New grant allows Vora to collaborate with Duke to identify novel genes critical to human brain development

Neeta Vora, MD, associate professor of obstetrics and gynecology in the division of maternal-fetal medicine, and Erica Davis, PhD, at the Duke University Center for Human Disease Modeling, have been awarded an exploratory/developmental research grant (R21) from the National Center for Advancing Translational Sciences.

New grant allows Vora to collaborate with Duke to identify novel genes critical to human brain development - Read More…

Discovery Shows How Mucus Build-up, Not Infections, Triggers Cystic Fibrosis Lung Damage

Discovery Shows How Mucus Build-up, Not Infections, Triggers Cystic Fibrosis Lung Damage

Giving mucus-thinning therapies in early childhood might delay the worst symptoms and infections associated with CF, according to a study led by Charles Esther, MD, PhD, and Marianne Muhlebach, MD. Their paper is the cover story of Science Translational Medicine.

Discovery Shows How Mucus Build-up, Not Infections, Triggers Cystic Fibrosis Lung Damage - Read More…

UNC Ophthalmology Team First to Describe Glaucoma Incidence in Africa

UNC Ophthalmology Team First to Describe Glaucoma Incidence in Africa

Glaucoma is the leading cause of irreversible blindness worldwide and affects people of African descent disproportionately. A team of researchers from UNC Ophthalmology has published findings in the March 2019 issue of Ophthalmology demonstrating the highest incidence of glaucoma in the world in Ghana, West Africa.

UNC Ophthalmology Team First to Describe Glaucoma Incidence in Africa - Read More…

Carter's work on the origins of life featured on Scipod episode

Carter's work on the origins of life featured on Scipod episode

Ever wonder how chemicals turned into biology all those billions of years ago? Charles Carter, PhD, professor of biochemistry and biophysics, has conducted research to shed light on this ancient mystery.

Carter's work on the origins of life featured on Scipod episode - Read More…

Precision oncology insights revealed for colorectal cancer

The findings, published in the Journal of Clinical Oncology, could help define strategies to more effectively treat colorectal cancer, the second leading cause of cancer death in the United States. The analysis was led by UNC Lineberger’s Federico Innocenti, MD, PhD.

Precision oncology insights revealed for colorectal cancer - Read More…

Itano Earns CZI Grant to support Imaging Scientists

Itano Earns CZI Grant to support Imaging Scientists

The Chan Zuckerberg Initiative will support the innovative imaging work of Michelle Itano, PhD, director of the UNC Neuroscience Microscopy Core facility, for five years thanks to a grant totaling nearly $800,000.

Itano Earns CZI Grant to support Imaging Scientists - Read More…

FDA Approves ZULRESSO™ (brexanolone) Injection for Postpartum Depression Following Three Clinical Trials Led by UNC Researcher

FDA Approves ZULRESSO™ (brexanolone) Injection for Postpartum Depression Following Three Clinical Trials Led by UNC Researcher

ZULRESSO, developed by Sage Therapeutics, is the first and only treatment specifically indicated to treat postpartum depression in women. UNC School of Medicine’s Samantha Meltzer-Brody, MD, MPH, was the principal investigator for three clinical trials showing rapid-reduction in depressive symptoms, and says the approval marks a major step forward in women’s healthcare.

FDA Approves ZULRESSO™ (brexanolone) Injection for Postpartum Depression Following Three Clinical Trials Led by UNC Researcher - Read More…

AI and MRIs at birth can predict cognitive development at age 2, UNC study finds

AI and MRIs at birth can predict cognitive development at age 2, UNC study finds

Findings by UNC researchers may help identify children at risk shortly after birth, making early intervention possible; John H. Gilmore, MD, from the department of psychiatry is senior author.

AI and MRIs at birth can predict cognitive development at age 2, UNC study finds - Read More…

Brain Stimulation Improves Depression Symptoms, Restores Brain Waves in Clinical Study

Brain Stimulation Improves Depression Symptoms, Restores Brain Waves in Clinical Study

UNC School of Medicine researchers led by Flavio Frohlich, PhD, are the first to use transcranial alternating current brain stimulation (tACS) to significantly reduce symptoms in people diagnosed with major depression.

Brain Stimulation Improves Depression Symptoms, Restores Brain Waves in Clinical Study - Read More…

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