Research

The latest research news from UNC Health Care and the UNC School of Medicine.

A new era for genetic interpretation

A new era for genetic interpretation

UNC Lineberger researchers are collaborating through the ClinGen consortium to pinpoint disease-causing genetic variants

A new era for genetic interpretation - Read More…

Carolina, GSK announce novel partnership to accelerate search for HIV cure

Carolina, GSK announce novel partnership to accelerate search for HIV cure

The HIV Cure center will be located on the UNC-Chapel Hill campus and will focus exclusively on finding a cure for HIV/AIDS.

Carolina, GSK announce novel partnership to accelerate search for HIV cure - Read More…

UNC analysis shows advantage for picture-based cigarette pack warnings over text warnings

UNC analysis shows advantage for picture-based cigarette pack warnings over text warnings

A University of North Carolina at Chapel Hill analysis published today in the journal Tobacco Control synthesized the results of 37 different experiments comparing picture-based and text warnings, finding that picture-based warnings were more effective than text warnings on 20 of 25 different outcome measures.

UNC analysis shows advantage for picture-based cigarette pack warnings over text warnings - Read More…

Popular electric brain stimulation method detrimental to IQ scores

Popular electric brain stimulation method detrimental to IQ scores

In a double-blinded, randomized study, UNC researchers found that the IQ scores of people who underwent tDCS brain stimulation improved markedly less than did the IQ scores of people in the placebo group.

Popular electric brain stimulation method detrimental to IQ scores - Read More…

UNC faculty author four key publications in gastroenterology and hepatology

UNC faculty author four key publications in gastroenterology and hepatology

According to a list recently published in the Annals of Internal Medicine, UNC Gastroenterology and Hepatology faculty authored four of the 12 key publications in gastroenterology and hepatology published in 2014.

UNC faculty author four key publications in gastroenterology and hepatology - Read More…

UNC Lineberger study finds new potential melanoma drug target

UNC Lineberger study finds new potential melanoma drug target

A new treatment for melanoma could be on the horizon, thanks to a finding by a UNC Lineberger Comprehensive Cancer Center-led team. In the study, which was published online today in the journal Clinical Cancer Research, the authors report that they found high levels of an enzyme in melanoma samples that they believe is a potential drug target.

UNC Lineberger study finds new potential melanoma drug target - Read More…

UNC researchers create DNA repair map of the entire human genome

UNC researchers create DNA repair map of the entire human genome

The new experimental assay can help scientists find the precise locations of repair of DNA damage caused by UV radiation and common chemotherapies. The invention could lead to better cancer drugs or improvements in the potency of existing ones.

UNC researchers create DNA repair map of the entire human genome - Read More…

Building Pipelines of Physician-Scientists

Building Pipelines of Physician-Scientists

We may be rivals on the court, but believe it or not, UNC and Duke share many of the same values. Take, for example, the MD-PhD students at both schools who are working together and building mentorship programs for undergraduates interested in pursuing the dual-degree.

Building Pipelines of Physician-Scientists - Read More…

A BRAIN Initiative first: new tool can switch behavior ‘on’ and ‘off’

A BRAIN Initiative first: new tool can switch behavior ‘on’ and ‘off’

Using a new ‘chemogenetic’ technique invented at UNC, scientists turn neurons ‘on’ and ‘off’ to demonstrate how brain circuits control behavior in mice. This unique tool – the first to result from the NIH BRAIN Initiative – will help scientists understand how to modulate neurons to more effectively treat diseases.

A BRAIN Initiative first: new tool can switch behavior ‘on’ and ‘off’ - Read More…

O’Brien Honored with Distinguished Andrologist Award

O’Brien Honored with Distinguished Andrologist Award

The American Society of Andrology recognized O’Brien’s research on male fertility.

O’Brien Honored with Distinguished Andrologist Award - Read More…

Three UNC School of Medicine faculty awarded PCORI contracts

Three UNC School of Medicine faculty awarded PCORI contracts

The Patient-Centered Outcomes Research Institute has awarded contracts totaling more than $12 million to Michael Kappelman, Kelli Allen and Donna Evon. The largest of the three awards, to Dr. Kappelman, is a 5-year, $8 million contract to compare the effectiveness of two drug therapies in the treatment of Crohn’s disease in children.

Three UNC School of Medicine faculty awarded PCORI contracts - Read More…

Student-run symposium focuses on translational medicine

Student-run symposium focuses on translational medicine

The sixth annual Translational Medicine Symposium was held this week at the Koury Oral Health Sciences Building at UNC. The event features students trained to engage in the clinical side of research

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Cirrhosis deaths drop 41 percent from 2002 to 2012

Cirrhosis deaths drop 41 percent from 2002 to 2012

A new study by UNC researchers has found dramatic improvements in the care of patients with cirrhosis and liver failure and recommends improved treatment strategies for patients with cirrhosis and concurrent bacterial infections.

Cirrhosis deaths drop 41 percent from 2002 to 2012 - Read More…

The Family Disease

The Family Disease

Cystic fibrosis took five of her siblings at a young age. Now, Wanda O’Neal, PhD, is part of a team of UNC researchers searching for reasons why. Their latest work has provided new insights that will help unravel why a sixth sibling with CF is living a productive life as he turns 50.

The Family Disease - Read More…

Scientists use brain stimulation to boost creativity, set stage to potentially treat depression

Scientists use brain stimulation to boost creativity, set stage to potentially treat depression

Using a weak electric current to alter a specific brain activity pattern, UNC School of Medicine researchers increased creativity in healthy adults. Now they’re testing the same experimental protocol to alleviate symptoms in people with depression.

Scientists use brain stimulation to boost creativity, set stage to potentially treat depression - Read More…

The Man from Kansas

The Man from Kansas

Born in a former frontier town, UNC graduate student Patrick McCarter explores how our cells respond to dangerous changes in their environment.

The Man from Kansas - Read More…

Lower survival rates connected with high-risk melanoma with mutations, study finds

Lower survival rates connected with high-risk melanoma with mutations, study finds

A UNC Lineberger-led study found that people with higher-risk melanoma containing either BRAF or NRAS gene mutations had lower survival rates.

Lower survival rates connected with high-risk melanoma with mutations, study finds - Read More…

Researchers find new approach to treat drug-resistant HER2-positive breast cancer

Researchers find new approach to treat drug-resistant HER2-positive breast cancer

Using human cancer cell lines, UNC scientists identified various ways that HER2-positive breast cancer tumors resist therapy, and they discovered a potential combination therapy to overcome multiple mechanisms of resistance and kill cancer cells.

Researchers find new approach to treat drug-resistant HER2-positive breast cancer - Read More…

UNC Lineberger sequences 10,000 tumors as part of national cancer genomics effort

UNC Lineberger sequences 10,000 tumors as part of national cancer genomics effort

UNC sequenced the RNA for 10,000 tumor samples as part of The Cancer Genome Atlas project, a National Cancer Institute and National Human Genome Research Institute backed effort to create a comprehensive atlas of the genetic changes in cancer.

UNC Lineberger sequences 10,000 tumors as part of national cancer genomics effort - Read More…

UNC-Duke collaboration probes the depths of gut health

UNC-Duke collaboration probes the depths of gut health

UNC stem cell expert Scott Magness, PhD, and Duke microbiome researcher John Rawls, PhD, are using a $50,000 grant to develop a new technology to study the co-dependent relationship between the human gut and its resident bacteria.

UNC-Duke collaboration probes the depths of gut health - Read More…

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