Research

The latest research news from UNC Health Care and the UNC School of Medicine.

Study finds links between physicians setting cancer care guidelines and drug industry

Study finds links between physicians setting cancer care guidelines and drug industry

UNC Lineberger researchers, led by Aaron Mitchell, MD, found a high prevalence of financial relationships among authors who helped develop a leading set of cancer care guidelines in the United States in a study published in JAMA Oncology. They say the work lays the foundation for future studies of whether the payments influenced clinical practice or guideline recommendations.

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Researchers question process for reviewing coverage of ‘off label’ cancer drug use

Researchers question process for reviewing coverage of ‘off label’ cancer drug use

In a paper published online by the Journal of the American Medical Association, UNC Lineberger physician-researchers led by Ethan Basch, MD, MSc, raised concerns that there are inconsistencies between the five reference guides, or compendia, that the Centers for Medicare and Medicaid Services uses to determine which drugs it will reimburse for off-label uses in cancer care.

Researchers question process for reviewing coverage of ‘off label’ cancer drug use - Read More…

UNC PREP reports impressive results

UNC PREP reports impressive results

Newly released research shows that the UNC Postbaccalaureate Research Education Program (PREP) is setting a high standard for the other 31 NIH-funded PREP programs across the country.

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Tucker provides recommendations for improving patient-physician trust in China

Tucker provides recommendations for improving patient-physician trust in China

Responding to the endemic mistrust between patients and physicians in China, Joseph D. Tucker, MD, PhD, assistant professor of Medicine, and director of UNC Project-China, organized an initiative to rebuild patient-physician trust.

Tucker provides recommendations for improving patient-physician trust in China - Read More…

UNC researchers investigate health coverage gap for inmates

The state in which a prisoner resides impacts their access to health care, according to researchers at the University of North Carolina at Chapel Hill.

UNC researchers investigate health coverage gap for inmates - Read More…

Majority of parents support HPV vaccination requirements for school, but only with opt-outs

Majority of parents support HPV vaccination requirements for school, but only with opt-outs

A national survey found that parents were more likely to agree that laws requiring students to be vaccinated against HPV for school entry are a “good idea” when there is an opt-out clause.

Majority of parents support HPV vaccination requirements for school, but only with opt-outs - Read More…

Researchers use genetics to probe immune system’s role in fighting cancer

Researchers use genetics to probe immune system’s role in fighting cancer

Findings published in the Journal of the National Cancer Institute show that immune cells do not respond the same way to all tumor types. The study, led by UNC Lineberger researcher Benjamin Vincent, MD, could lay the foundation for the discovery of biomarkers to determine which patients might respond to certain immune-stimulating cancer treatments.

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Challenging the status quo: Katz examines training, staffing and research in cardiac intensive care

Challenging the status quo: Katz examines training, staffing and research in cardiac intensive care

Jason Katz, MD, MHS, medical director of UNC’s cardiac intensive care unit, examines the challenges facing cardiac intensive care units and clinicians, and offers innovative recommendations for training, staffing and research for this emerging field.

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How do antidepressants trigger fear and anxiety?

How do antidepressants trigger fear and anxiety?

UNC School of Medicine researchers map the anxiety circuit in the brain and use a compound to limit fearful behavior – an acute side effect of commonly prescribed SSRI antidepressants.

How do antidepressants trigger fear and anxiety? - Read More…

North Carolina Jaycee Burn Center receives FEMA grant

This funding, which is administered under the FEMA Assistance to Firefighters Grant Program, will be used to educate lower-income North Carolinians about fire safety and train first responders in burn treatment.

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Investigating the presence of sex bias in human surgical clinical research

Investigating the presence of sex bias in human surgical clinical research

In a study published in JAMA Surgery, Melina Kibbe, MD, Zach D. Owens Professor and Chair, Department of Surgery, and colleagues found that few human surgical clinical research studies included men and women equally.

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UNC scientist’s drive for a cancer cure inspired by the father he doesn’t remember

UNC scientist’s drive for a cancer cure inspired by the father he doesn’t remember

Zhen Gu, a biomedical engineer at the University of North Carolina and N.C. State University, is featured in STAT News for his work on cancer.

UNC scientist’s drive for a cancer cure inspired by the father he doesn’t remember - Read More…

Miami professor bicycles to Chapel Hill to raise awareness for Angelman syndrome

Miami professor bicycles to Chapel Hill to raise awareness for Angelman syndrome

Kellen Hassell, EdD, raised more than $15,000 and donated it to UNC’s clinical and research efforts to tackle the rare neurodevelopmental disorder.

Miami professor bicycles to Chapel Hill to raise awareness for Angelman syndrome - Read More…

Roadblocks to research: UNC bioethicist addresses lack of HIV studies in pregnant women

Roadblocks to research: UNC bioethicist addresses lack of HIV studies in pregnant women

With a $3 million NIH grant, Anne Lyerly, MD, MA, leads an interdisciplinary team of researchers to determine what barriers prevent investigators from studying the virus in pregnant women.

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Researchers build a better opioid painkiller from scratch

Researchers build a better opioid painkiller from scratch

The new compound could reduce overdoses and possibly curb addiction, while addressing the needs of millions of people suffering with chronic pain.

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Zika vaccine development: UNC researchers seeking individuals exposed to arboviruses

Zika vaccine development: UNC researchers seeking individuals exposed to arboviruses

Drs. Aravinda de Silva and Matt Collins hope to use blood samples from people who have been previously diagnosed with or potentially exposed to specific viruses as part of their vaccine development work.

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UNC researchers home in on promising treatment for peanut allergy

UNC researchers home in on promising treatment for peanut allergy

The first-ever clinical study of preschoolers allergic to peanuts could lead to safe and effective treatment for millions of people.

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Insurance, distance to care can be barriers to breast reconstruction

Insurance, distance to care can be barriers to breast reconstruction

Researchers say breast reconstruction can help with self-esteem, sexuality and body image after cancer treatment. But a UNC Lineberger study led by Michelle Roughton, MD, has found that the type of insurance a woman has as well as distance to a plastic surgeon's office can be barriers to the procedure.

Insurance, distance to care can be barriers to breast reconstruction - Read More…

No dream: electric brain stimulation during sleep can boost memory

No dream: electric brain stimulation during sleep can boost memory

By targeting one facet of the brain’s electrical activity, UNC neuroscientist Flavio Frohlich, PhD, showed it’s possible to enhance memory, laying the groundwork for a new treatment paradigm for neurological and psychiatric disorders.

No dream: electric brain stimulation during sleep can boost memory - Read More…

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