Research

The latest research news from UNC Health Care and the UNC School of Medicine.

The Proof is in the Pudding

The Proof is in the Pudding

Temperance Rowell delves into the flavored world of e-cigarettes to investigate the long-term effects of a new trend.

The Proof is in the Pudding - Read More…

UNC’s Wolfgang Bergmeier, PhD, earns Bridge Grant

UNC’s Wolfgang Bergmeier, PhD, earns Bridge Grant

The American Society of Hematology fills gap in decreased federal funding, supports 13 blood research projects.

UNC’s Wolfgang Bergmeier, PhD, earns Bridge Grant - Read More…

Biomedical engineer Zhen Gu, PhD, tabbed as top young innovator

Biomedical engineer Zhen Gu, PhD, tabbed as top young innovator

The editors of the MIT Technology Review highlighted Gu’s work on a novel way to monitor and treat diabetes.

Biomedical engineer Zhen Gu, PhD, tabbed as top young innovator - Read More…

Diabetes drug metformin’s primary effect is in the gut, not the bloodstream

Diabetes drug metformin’s primary effect is in the gut, not the bloodstream

New study in Diabetes Care suggests new delayed-release metformin could help 40 percent of type 2 diabetes patients that currently can’t take metformin.

Diabetes drug metformin’s primary effect is in the gut, not the bloodstream - Read More…

New study to explore possible links between gut bacteria and eating disorders

New study to explore possible links between gut bacteria and eating disorders

UNC’s part in the study is led by Dr. Cynthia M. Bulik, Distinguished Professor of Eating Disorders in the Department of Psychiatry in the School of Medicine, a Professor of Nutrition in the Gillings School of Global Public Health, and Founding Director of the UNC Center of Excellence for Eating Disorders.

New study to explore possible links between gut bacteria and eating disorders - Read More…

Landmark study validates method for patient reporting of cancer drug-related adverse events

Landmark study validates method for patient reporting of cancer drug-related adverse events

In an article published in JAMA Oncology today, a study led by UNC Lineberger's Ethan Basch and colleagues shows that a system they developed accurately and reliably captures the patient experience with cancer drug side effects.

Landmark study validates method for patient reporting of cancer drug-related adverse events - Read More…

Comprehending Chemotaxis

Comprehending Chemotaxis

James Bear, PhD, uncovers the intricate mechanisms that allow certain cells to move, discoveries with implications for cancer metastasis.

Comprehending Chemotaxis - Read More…

New study shows microRNA control of cholesterol and fat

A new study from UNC researchers in the department of genetics identifies a microRNA molecule (miR-29) that controls the levels of cholesterol and fat in the bloodstream by regulating the amount of cholesterol and fat production in the liver. The study is published in Nature's open access journal, Scientific Reports.

New study shows microRNA control of cholesterol and fat - Read More…

Scientists identify gene vital for rebuilding intestine after cancer treatment

Protecting the gastrointestinal system during chemotherapy or radiation could allow patients to tolerate more aggressive treatments to attack tumors.

Scientists identify gene vital for rebuilding intestine after cancer treatment - Read More…

UNC scientists pinpoint how a single genetic mutation increases autism risk

UNC scientists pinpoint how a single genetic mutation increases autism risk

The research shows the precise cellular mechanisms that could increase risk for the disorder and how an existing drug might help thousands of people with autism.

UNC scientists pinpoint how a single genetic mutation increases autism risk - Read More…

 Early Antiretroviral Therapy Protects Sero-Discordant Couples from Transmission of HIV to Their Uninfected Partner

Early Antiretroviral Therapy Protects Sero-Discordant Couples from Transmission of HIV to Their Uninfected Partner

These findings demonstrate that antiretroviral therapy, when taken until viral suppression is achieved and sustained, is a highly effective, durable intervention for HIV prevention.

Early Antiretroviral Therapy Protects Sero-Discordant Couples from Transmission of HIV to Their Uninfected Partner - Read More…

UNC researchers earn prestigious Keck award for cell cycle map

The labs of Jean Cook, PhD, and Jeremy Purvis, PhD, will develop the first-ever interactive molecular model of a crucial cellular process that controls healthy growth and diseases such as cancer.

UNC researchers earn prestigious Keck award for cell cycle map - Read More…

New antibody portal bolsters biomedical research reliability

New antibody portal bolsters biomedical research reliability

UNC’s Brian Strahl, PhD, and Van Andel Research Institute’s Scott Rothbart, PhD, create a robust online interactive database to address science’s ‘antibody crisis’.

New antibody portal bolsters biomedical research reliability - Read More…

Vora co-authors JAMA study on noninvasive prenatal tests and the detection of maternal cancers

Noninvasive prenatal screening tests may detect underlying maternal conditions, including cancer, in the mother, according to a study published July 13 in the Journal of the American Medical Association on which Dr. Neeta Vora, a clinical geneticist and assistant professor of maternal-fetal medicine at UNC's Department of Obstetrics and Gynecology, is co-author.

Vora co-authors JAMA study on noninvasive prenatal tests and the detection of maternal cancers - Read More…

Is Facebook use always associated with poorer body image and risky dieting?

Is Facebook use always associated with poorer body image and risky dieting?

A survey of college-aged women finds that those with the strongest emotional connection to Facebook are less likely to struggle with risky dieting behaviors compared to their peers.

Is Facebook use always associated with poorer body image and risky dieting? - Read More…

UNC researchers find two biomarkers linked to severe heart disease

UNC researchers find two biomarkers linked to severe heart disease

The finding published in PLoS One suggests that elevated oxidized LDL cholesterol and fructosamine – a measure of glycated proteins in blood sugar – are signposts for the development of severe coronary disease, especially in females.

UNC researchers find two biomarkers linked to severe heart disease - Read More…

UNC doctors analyze treatment options for gallbladder disease

UNC doctors analyze treatment options for gallbladder disease

Their article, published in The New England Journal of Medicine, explores the pros and cons of five different interventional approaches to treating gallbladder disease – a condition that affects more than 25 million Americans.

UNC doctors analyze treatment options for gallbladder disease - Read More…

New web-based calculator better interprets prenatal genetic test results

UNC OB-GYN's Division of Maternal-Fetal Medicine has unveiled a free, web-based calculator to help providers better counsel patients on the benefits and risks of the four most common screening tools for fetal genetic abnormalities available commercially in the U.S.

New web-based calculator better interprets prenatal genetic test results - Read More…

Imaging Beyond Anatomy

Imaging Beyond Anatomy

A UNC core facility churns out radioactive agents to investigate the subcellular activity that drives disease.

Imaging Beyond Anatomy - Read More…

New Publication Evaluates End Points for Clinical Trials

New Publication Evaluates End Points for Clinical Trials

Clinical trials studying kidney disease usually use end-stage kidney disease as the primary outcome, or end point, of a study. For many kidney diseases end-stage kidney disease may not occur for several years, sometimes 10 or more. A new paper examines surrogate endpoints. Patrick Nachman, MD, of the UNC Kidney Center, is one of the paper's authors.

New Publication Evaluates End Points for Clinical Trials - Read More…

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