Research

The latest research news from UNC Health Care and the UNC School of Medicine.

Group led by UNC physician writes patient safety bundle for hypertension in pregnant women

Group led by UNC physician writes patient safety bundle for hypertension in pregnant women

Kathryn Menard, MD, MPH, director of maternal-fetal medicine at UNC, was lead author on the commentary, which makes 14 specific recommendations on how best to address the needs of pregnant and recently postpartum women who face a sudden spike in blood pressure.

Group led by UNC physician writes patient safety bundle for hypertension in pregnant women - Read More…

Mario Capecchi will give keynote talk at Smithies Nobel Symposium

Mario Capecchi will give keynote talk at Smithies Nobel Symposium

Mark your calendars for September 19 at 3 p.m. for a talk by Italian scientist Mario Capecchi, who won the 2007 Nobel Prize in Physiology or Medicine with Martin Evans and our own Oliver Smithies.

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Researchers find genetic precursors of leukemia in patients treated for non-blood cancers

Researchers find genetic precursors of leukemia in patients treated for non-blood cancers

A study led by UNC Lineberger's Catherine Coombs, MD, revealed new risk factors for “clonal hematopoiesis,” a medical phenomenon in which genetic mutations are found in the blood cells of patients who do not have an existing blood cancer.

Researchers find genetic precursors of leukemia in patients treated for non-blood cancers - Read More…

Researchers look to improve detection of skin cancer lacking pigment melanin

Researchers look to improve detection of skin cancer lacking pigment melanin

UNC Lineberger researchers led by Nancy Thomas, MD, PhD, have identified key features linked to amelanotic melanoma, a form of skin cancer that lacks the brown or black color that stems from the pigment melanin.

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Thanks to a UNC research project, she can walk again

Thanks to a UNC research project, she can walk again

As UNC geneticist Jonathan Berg gears up to lead a $9.7-million renewal of the NCGENES project, we look at a story from the original study and how it changed the fortunes of a woman from Goldsboro, NC.

Thanks to a UNC research project, she can walk again - Read More…

Aggressive breast cancers may contribute to racial survival disparities

Aggressive breast cancers may contribute to racial survival disparities

In the Journal of the National Cancer Institute, UNC Lineberger researchers led by Melissa Troester, PhD, published results of an analysis of approximately 1,000 invasive breast tumors. The study confirmed that young black women are more likely to have “triple negative,” or “basal-like,” breast cancers, a subtype that does not express any of the receptors for targeted biologic therapies. The study also identified variation by race within a clinical breast cancer type that has the greatest mortality disparity.

Aggressive breast cancers may contribute to racial survival disparities - Read More…

Magnuson Signs Research Code of Conduct

On June 8, 2017, Vice Chancellor for Research Terry Magnuson officially approved UNC’s Code and Standard of Research Conduct. With his signature and concurrence by the Faculty Council and Policy Review Committee, the University of North Carolina at Chapel Hill joins other premier research universities in formalizing the high standards that it expects from members of the research community.

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Research shows acupuncture could offer relief for patients with esophageal disorders

Research shows acupuncture could offer relief for patients with esophageal disorders

Preliminary research led by Marco Patti, MD, professor of surgery, and collaborators in Brazil, has shown that acupuncture could offer relief for patients suffering from swallowing disorders such as achalasia.

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TARC receives $4M for two osteoarthritis research projects

TARC receives $4M for two osteoarthritis research projects

Richard Loeser, MD, a rheumatologist and investigator who heads the UNC Thurston Arthritis Research Center, has been awarded grants totaling $4 million from the National Institutes of Health (NIH) for two osteoarthritis projects.

TARC receives $4M for two osteoarthritis research projects - Read More…

Scientists create stem cell therapy for lung fibrosis conditions

Scientists create stem cell therapy for lung fibrosis conditions

Through a joint UNC School of Medicine-NC State research project shows how to harvest lung stem cells non-invasively and then multiply healthy cells – a potential powerful therapy against inflammatory lung conditions.

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Vorinostat Renders Dormant HIV Infection Vulnerable to Clearance

Vorinostat Renders Dormant HIV Infection Vulnerable to Clearance

The ability for HIV to hide in the body in a dormant state makes curing the 40 million people living with the virus a challenge. Researchers at the University of North Carolina at Chapel Hill have shown the drug Vorinostat reverses this latency, causing resting CD4 T-cells to express HIV.

Vorinostat Renders Dormant HIV Infection Vulnerable to Clearance - Read More…

Ebola Detected in Semen of Survivors Two Years after Infection

Ebola Detected in Semen of Survivors Two Years after Infection

Ebola virus RNA can persist in the semen of survivors more than two years after the onset of infection researchers at the University of North Carolina at Chapel Hill have found.

Ebola Detected in Semen of Survivors Two Years after Infection - Read More…

UNC teams with Verily Life Sciences to study trauma recovery

UNC teams with Verily Life Sciences to study trauma recovery

The Verily Study Watch will help researchers at the UNC School of Medicine and across the country collect first-in-kind data to better understand and diagnose adverse brain outcomes after trauma.

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UNC scientist to lead $10-million project to build brain-imaging technology

UNC scientist to lead $10-million project to build brain-imaging technology

The five-year NSF project led by UNC researcher Spencer Smith will develop new imaging systems and technology to explore the brain like never before.

UNC scientist to lead $10-million project to build brain-imaging technology - Read More…

UNC to Test Therapeutic Vaccine in People Living with HIV

A multidisciplinary research team at the University of North Carolina at Chapel Hill has been awarded more than $5.6 million from the National Institutes of Health (NIH) to test a therapeutic vaccine in people living with HIV.

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UNC Study Advances the Ability to Expose Latent HIV

UNC Study Advances the Ability to Expose Latent HIV

UNC researchers led by Nancie Archin, PhD, and David Margolis, MD, have shown that interval dosing of the drug Vorinostat reverses HIV latency and is well-tolerated in people living with HIV. However, while Vorinostat makes latent HIV easier to detect, it does not clear or deplete infection, meaning additional advances will be needed to achieve a cure. These results were published in the Journal of Clinical Investigation on July 17.

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Toddler Brain Development: bacterial clues found in dirty baby diapers

Toddler Brain Development: bacterial clues found in dirty baby diapers

Can the kinds of microbes colonizing the gut at age 1 predict later cognitive development? Findings from the UNC School of Medicine shed light on the surprising role of bacteria in how our brains develop during the first years of life.

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Teen ACL injuries on the rise, UNC researchers call for wider use of injury prevention programs

Teen ACL injuries on the rise, UNC researchers call for wider use of injury prevention programs

New research from UNC shows that rates of anterior cruciate ligament (ACL) reconstruction are increasing sharply, with the most dramatic increase among girls aged 13-17.

Teen ACL injuries on the rise, UNC researchers call for wider use of injury prevention programs - Read More…

Pregnant women should be included in Zika virus vaccine research, new guidance says

Pregnant women should be included in Zika virus vaccine research, new guidance says

The inclusion of pregnant women in Zika virus vaccine research is crucial to solving the international health crisis, according to new guidance published by UNC’s Center for Bioethics and two other universities.

Pregnant women should be included in Zika virus vaccine research, new guidance says - Read More…

ALS: New Clues to the Cause and How Future Drugs Might Reverse Disease

ALS: New Clues to the Cause and How Future Drugs Might Reverse Disease

UNC and NC State researchers team up to reverse TDP-43 protein aggregation, a hallmark of degenerative diseases.

ALS: New Clues to the Cause and How Future Drugs Might Reverse Disease - Read More…

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