In lab experiments, North Carolina researchers developed the first patch to monitor blood viscosity and release blood thinning medication as needed.
The drug, called SelG1, also reduced the frequency of pain crises in people with sickle cell disease and reduced the number of days they spent in the hospital.
Led by John Buse, MD, PhD, director of the UNC Diabetes Care Center, the clinical research of UNC doctors and the participation of thousands of patients culminates in a new, effective, and safe daily injectable drug to combat type-2 diabetes.
UNC Lineberger researchers led by Adam Goldstein, MD, MPH, concluded in a study published in Tobacco Control that banning non-menthol flavors like fruit and candy could reduce use of most tobacco products across the globe, especially among adolescents.
A study at the University of North Carolina found that gene deletion poses a threat to Malaria eradication efforts.
Dr. Thomas Keyserling and Dr. Greg Randolph from the UNC School of Medicine are investigators in the project.
On Nov. 11, the UNC School of Medicine celebrated the 48th annual Student Research Day, hosted by the John B. Graham Student Research Society.
The basic biological process called alternative splicing proves vital in making sure important muscle cell proteins switch from their fetal forms to their adult forms. Not doing so could lead to muscle defects and disorders.
Inspired by a genetic discovery by her PhD mentor, UNC heart researcher Li Qian followed the ‘Tinman’ down the yellow brick road to an award-winning career in science, including the Jefferson-Pilot Fellowship in Academic Medicine.
UNC School of Medicine researchers Aravinda de Silva, PhD, professor of microbiology and immunology, and Stefan Metz, PhD, are creating a nanoparticle vaccine that in experiments showed increased antibody responses against one serotype of dengue virus. The de Silva group is collaborating with the UNC laboratories of Chris Luft, PhD, (pharmacy and chemistry), Jenny Ting, PhD, (genetics), and Mike Miley,PhD, (pharmacology), as well as Liquidia Pharmaceuticals to use the same nanoparticle platform to develop a vaccine for all four serotypes of the virus.
At this year’s Smithies Nobel Symposium lecture, Stanford’s Brian Kobilka spoke on the importance of GPCRs in drug development.
The UNC School of Medicine was one of two U.S. institutions named to an international research consortium funded through the European Union’s Horizon 2020 Programme, which invested $49 million in Zika research and vaccine development at more than 20 laboratories in Europe and Brazil.
Research conducted by a nationwide team, including the UNC School of Medicine's Stephen Hooper, PhD, found associations between hypertension and cognitive issues in children. The research was published in The Journal of Pediatrics and also highlighted by The New York Times in a recent article.
UNC Lineberger researchers led by Dr. Timothy R. Gershon report preclinical findings showing promise for targeting a gene linked to microcephaly in infants as a treatment for medulloblastoma.
In the journal Cancer Epidemiology, Biomarkers & Prevention, researchers report that uninsured women under age 65 who received their mammogram at community screening clinics in North Carolina were less likely to get follow-up within a year of a positive mammogram, and had higher odds of missing a 60-day window for follow-up care.
Variants of the human version of the gene may help explain why people differ so much in their ability to survive artery blockages.
Study led by UNC researchers compared group therapy delivered via online chat to face-to-face group therapy
Adewole S. Adamson, MD, assistant professor of dermatology at the UNC School of Medicine, found that patients given electronic prescriptions were more likely to pick up and fill their dermatological prescriptions than those patients who were given a traditional, written prescription.
In a new video produced by the Higher Education Works Foundation, UNC Chancellor Carol Folt touts the many research accomplishments seen on campus over the past few years, specifically citing work in biomedical science and cancer research.
National Institute of Justice funds research to develop a tool to identify abuse in this setting.