Research

The latest research news from UNC Health Care and the UNC School of Medicine.

Researchers implicate suspect in heart disease linked to diabetes

Researchers implicate suspect in heart disease linked to diabetes

In their study of the IRS-1 protein, researchers at the University of North Carolina found a new lead for reversing or preventing heart disease associated with diabetes.

Researchers implicate suspect in heart disease linked to diabetes - Read More…

 Patients and their records agree on medical history for most maladies

Patients and their records agree on medical history for most maladies

A study led by UNC Lineberger researcher Ronald Chen, MD, found that a group of prostate cancer patients reliably reported their own medical histories when their responses were compared to their medical records.

Patients and their records agree on medical history for most maladies - Read More…

 Researchers awarded grant to study strategy to improve immunotherapy response

Researchers awarded grant to study strategy to improve immunotherapy response

With a $1.74 million grant from the NIH, UNC Lineberger researchers led by H. Shelton Earp, MD, will study a potential new strategy for improving immunotherapy drug responses in patients with melanoma.

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How Life Survives: UNC researchers confirm basic mechanism of DNA repair

How Life Survives: UNC researchers confirm basic mechanism of DNA repair

Findings come from an advanced DNA sequencing application developed by the lab of University of North Carolina Nobel Laureate Aziz Sancar.

How Life Survives: UNC researchers confirm basic mechanism of DNA repair - Read More…

UNC researchers find new potential route to treat asthma

UNC researchers find new potential route to treat asthma

Scientists at the UNC School of Medicine have identified and isolated a protein that could play a vital role in regulating proper airway function. When that protein is low in volume or missing altogether, it can cause airway hyper-reactivity in asthma.

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Manuck presents findings on key genes which may be involved in preterm birth

Manuck presents findings on key genes which may be involved in preterm birth

At the Society for Maternal-Fetal Medicine's annual meeting in Las Vegas, Tracy Manuck, MD, director of the UNC Prematurity Prevention Clinic, presented the findings of her study into a new method for filtering results from genetic studies, based on inheritance patterns across women of different racial and ethnic populations, in order to further determine risk of preterm birth.

Manuck presents findings on key genes which may be involved in preterm birth - Read More…

Revolutionary approach for treating glioblastoma works with human cells

Revolutionary approach for treating glioblastoma works with human cells

UNC-Chapel Hill researchers led by UNC Lineberger member Shawn Hingtgen, PhD, reach a critical milestone for treating brain cancer.

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UNC receives $2.5-million grant to explore new therapy for anhedonia

UNC receives $2.5-million grant to explore new therapy for anhedonia

As part of NIMH’s Experimental Therapeutics Initiative and led by Gabriel Dichter, PhD, researchers will use neuroimaging to evaluate a new treatment for decreased motivation and pleasure, symptoms that are common to many psychiatric disorders.

UNC receives $2.5-million grant to explore new therapy for anhedonia - Read More…

Scientists illuminate the neurons of social attraction

Scientists illuminate the neurons of social attraction

With a whiff of the opposite sex, these hormone-sensitive neurons trigger pro-social behavior in mice and could play roles in anxiety, depression, and other mood-related conditions in humans.

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Collaboration offers genetic testing for NC newborns

Collaboration offers genetic testing for NC newborns

A new NIH-funded consortium in North Carolina will offer Early Check, a free newborn screening done in partnership with the N.C. State Laboratory of Public Health, UNC, Duke University, and Wake Forest Baptist Medical Center.

Collaboration offers genetic testing for NC newborns - Read More…

New studies from the Taylor and Mack laboratories suggest novel therapeutic target for antihypertensive therapies

New studies from the Taylor and Mack laboratories suggest novel therapeutic target for antihypertensive therapies

In a recently published study, Joan Taylor, PhD, professor, Pathology and Laboratory Medicine, and associate director, McAllister Heart Institute, and Chris Mack, PhD, professor, Pathology and Laboratory Medicine, describe a novel therapeutic target for the development of antihypertensive therapies. The findings could prove useful for individualizing treatment regimens.

New studies from the Taylor and Mack laboratories suggest novel therapeutic target for antihypertensive therapies - Read More…

 Researchers unlock mechanism of drug resistance in aggressive breast cancer

Researchers unlock mechanism of drug resistance in aggressive breast cancer

UNC Lineberger researchers find how triple negative breast cancer cells are able to bypass treatment with trametinib, an FDA-approved drug. The researchers also used lab models of breast cancer to test a potential treatment approach that could prevent resistance.

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 U.S. cancer death rate declines, but work is needed to address local disparities

U.S. cancer death rate declines, but work is needed to address local disparities

UNC Lineberger researchers Ethan Basch, MD, MSc, and Stephanie Wheeler, PhD, MPH, called for tailored, local-level cancer prevention, screening and treatment efforts to address regional disparities in cancer mortality rates in an editorial published in JAMA on Tuesday.

U.S. cancer death rate declines, but work is needed to address local disparities - Read More…

This is LSD attached to a brain cell serotonin receptor

This is LSD attached to a brain cell serotonin receptor

For the first time, UNC School of Medicine researchers crystalized the structure of LSD attached to a human serotonin receptor of a brain cell, and they may have discovered why an “acid trip” lasts so long.

This is LSD attached to a brain cell serotonin receptor - Read More…

The Unintended Consequences of Centralized Blood Banking and What To Do About It

The Unintended Consequences of Centralized Blood Banking and What To Do About It

According to Anthony Charles, MD, MPH, of the UNC School of Medicine, the WHO should amend its centralization policy to help doctors save lives in Sub-Saharan Africa.

The Unintended Consequences of Centralized Blood Banking and What To Do About It - Read More…

A Gene’s Journey from Covert to Celebrated

A Gene’s Journey from Covert to Celebrated

Unmasking a previously misunderstood gene, University of North Carolina scientists discover an unlikely potential drug target for gastrointestinal cancers.

A Gene’s Journey from Covert to Celebrated - Read More…

Another molecular clue in the mysterious influence of microbiota in the gut

By focusing on small molecules called microRNAs in stem cells of the intestine, UNC School of Medicine researchers have proposed a new mechanism by which gut microbes might help keep us healthy or make us sick.

Another molecular clue in the mysterious influence of microbiota in the gut - Read More…

UV Light Can Aid Hospitals’ Fight to Wipe Out Drug-Resistant Superbugs

UV Light Can Aid Hospitals’ Fight to Wipe Out Drug-Resistant Superbugs

UNC's Dr. David Weber and Dr. William Rutala are co-authors of the study, which found that adding UV light to standard cleaning cut transmission of 4 resistant bacteria by 30 percent.

UV Light Can Aid Hospitals’ Fight to Wipe Out Drug-Resistant Superbugs - Read More…

Are you ready to explore baby’s genome?

Are you ready to explore baby’s genome?

UNC clinical geneticists are part of a national consortium of researchers studying the ins and outs of genome sequencing for newborn health screenings and beyond.

Are you ready to explore baby’s genome? - Read More…

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