Research

The latest research news from UNC Health Care and the UNC School of Medicine.

UNC researcher co-leads effort to map genomic changes in head and neck cancer

UNC researcher co-leads effort to map genomic changes in head and neck cancer

A study co-led by a UNC Lineberger Comprehensive Cancer Center researcher has identified genomic changes in head and neck cancers linked to the sexually transmitted disease HPV -- the latest finding of a collaborative scientific effort designed to map out the genomic changes driving cancer.

UNC researcher co-leads effort to map genomic changes in head and neck cancer - Read More…

New deep-brain imaging reveals separate functions for nearly identical neurons

New deep-brain imaging reveals separate functions for nearly identical neurons

For the first time, UNC neuroscientist Garret Stuber, PhD, imaged activity patterns of individual brain cells in freely moving mice to link specific basic behaviors to particular neurons.

New deep-brain imaging reveals separate functions for nearly identical neurons - Read More…

Systematic Review Series offered at Health Sciences Library

This spring, catch one or all of the Research Hub @ HSL’s six-part series on systematic reviews. The sessions will provide an introduction and walk attendees through topic refinement, power searching, tracking references, study selection and presentation of results.

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Researchers pinpoint two genes that trigger severest form of ovarian cancer

Researchers pinpoint two genes that trigger severest form of ovarian cancer

UNC geneticists led by Terry Magnuson, PhD, and Ron Chandler, PhD, create the first mouse model of ovarian clear cell carcinoma; show how a known drug can suppress tumor growth.

Researchers pinpoint two genes that trigger severest form of ovarian cancer - Read More…

MRIs link impaired brain activity to inability to regulate emotions in autism

MRIs link impaired brain activity to inability to regulate emotions in autism

UNC researchers find that the bigger the differences in brain activity related to emotion regulation, the more severe the autism. Gabriel Dichter, PhD, associate professor of psychiatry and psychology was the paper's senior author.

MRIs link impaired brain activity to inability to regulate emotions in autism - Read More…

Patient older age not an issue in revision cochlear implantation

Patient older age not an issue in revision cochlear implantation

Sometimes patients with coclear implants need to have a second or "revision" implantation surgery because of device failure. A new UNC study finds that adults age 65 and older do just as well in speech perception after revision cochlear implantation as those younger than 65.

Patient older age not an issue in revision cochlear implantation - Read More…

Diabetes researcher earns ADA grant to design nanoparticles to control blood sugar

Diabetes researcher earns ADA grant to design nanoparticles to control blood sugar

The research by Zhen Gu, PhD, assistant professor in the UNC-NCSU joint department of biomedical engineering, aims to improve methods for delivering precise amounts of medications less frequently.

Diabetes researcher earns ADA grant to design nanoparticles to control blood sugar - Read More…

Princeton’s David Tank wins Perl-UNC Neuroscience Prize

Princeton’s David Tank wins Perl-UNC Neuroscience Prize

Past winners include six scientists who went on to win the Nobel Prize in Physiology or Medicine

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Women who experience postpartum depression symptoms before giving birth may face greater risk

Women who experience postpartum depression symptoms before giving birth may face greater risk

Postpartum depression (PPD) may have a diverse clinical presentation and this has critical implications for diagnosis, treatment and understanding the underlying biology of the illness, a new study finds.

Women who experience postpartum depression symptoms before giving birth may face greater risk - Read More…

Parsing the Pathways

Parsing the Pathways

Graduate student Kathleen Mulvaney investigates the newly discovered interplay between two of the proteins that allow cells to divide.

Parsing the Pathways - Read More…

‘Flying carpet’ technique delivers one-two punch of anticancer drugs

‘Flying carpet’ technique delivers one-two punch of anticancer drugs

Researchers in the joint UNC-NCSU biomedical engineering department have used nanoscale graphene to improve upon traditional delivery of two cancer drugs.

‘Flying carpet’ technique delivers one-two punch of anticancer drugs - Read More…

Schizophrenia study No. 5 on 'Best of 2014' list

Schizophrenia study No. 5 on 'Best of 2014' list

Dr. Patrick Sullivan of UNC is a co-author of a study that is ranked No. 5 on a Best of 2014 list compiled by Dr. Tom Insel, director of the National Institute of Mental Health.

Schizophrenia study No. 5 on 'Best of 2014' list - Read More…

Roth’s novel research technique, DREADDs, lands him on Top 10 List

Roth’s novel research technique, DREADDs, lands him on Top 10 List

The National Institute of Mental Health director Tom Insel recognized Byran L. Roth, MD, PhD, for his innovative research tool.

Roth’s novel research technique, DREADDs, lands him on Top 10 List - Read More…

Margolis collaboration featured in The New Yorker

Margolis collaboration featured in The New Yorker

UNC School of Medicine researcher David Margolis, MD, was one of the first researchers to resist the common view that HIV is an incurable infection

Margolis collaboration featured in The New Yorker - Read More…

Two UNC doctors participating in Ebola clinical trial

Two UNC doctors participating in Ebola clinical trial

William A. Fischer II and David Wohl are taking part in a clinical trial at ELWA Hospital in Monrovia, Liberia, in which plasma from survivors of Ebola virus disease is given to patients who are battling the disease.

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Platforms for Proteins

Platforms for Proteins

Graduate student Orrin Stone is creating molecular tools to pinpoint how and when cellular pathways trigger cell movement – or, in cancer, metastasis.

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UNC researchers pinpoint chemo effect on brain cells, potential link to autism

UNC researchers pinpoint chemo effect on brain cells, potential link to autism

The common chemotherapy drug topotecan disrupts a gene integral for neuron communication, though the effects are reversible. The research also homes in on an underlying cause of autism.

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UNC neuroscientist part of first class of industry research grant winners

UNC neuroscientist part of first class of industry research grant winners

To support the NIH BRAIN Initiative, Garret Stuber, PhD, will use a new kind of microscope to further his lab’s investigation of brain circuits related to obesity.

UNC neuroscientist part of first class of industry research grant winners - Read More…

Lighting up Neurons

Lighting up Neurons

Garret Stuber, PhD, earns a UNC Hettleman prize for his research and promise as a young scientist uncovering the inner workings of the brain.

Lighting up Neurons - Read More…

Getting hip to vitamin D

Getting hip to vitamin D

A study led by John R. Stephens, MD, finds that simple interventions, consisting of a change in computerized order set and presentation of evidence and data from group practice, led to significant improvement in the assessment and treatment of vitamin D deficiency in elderly patients with hip fracture.

Getting hip to vitamin D - Read More…

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