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MHI Seminar Series presents Nadia Mercader, Ph.D., Professor, Developmental Biology and Regeneration, Institute of Anatomy, University of Bern, Bern, Switzerland
January 17 @ 10:00 am - 11:00 am
Summary of Seminar: In contrast to adult mammals, zebrafish have the capacity to regenerate their heart in response to a lesion. Following an injury, immune cells home to the heart, fibroblasts start to produce extracellular matrix, and endocardial cells contribute to rebuild the coronary vasculature. On top, cardiomyocytes start to proliferate and allow the regrowth of the lost myocardium through hyperplasia. One of the mechanisms that cardiomyocytes undergo to allow cell division is metabolic reprogramming. In this seminar, Dr. Mercader will discuss the interplay between fibrosis and cardiomyocyte proliferation. She will also explain how assembly of the mitochondrial respiratory chain influences the metabolic rewiring occurring in response to cardiac injury.
UNC Lineberger Comprehensive Cancer Center, Pagano Conference Room (LCCC 00-002)
450 West Dr.
Chapel Hill, North Carolina 27599
United States
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