MHI Seminar Series presents Walter Lee Murfee, III, PhD, from the J. Crayton Pruitt Family Department of Biomedical Engineering at the University of Florida

Summary of Seminar:  Understanding angiogenesis, similar to other physiological processes, requires identifying multiple cell, system, and environmental interactions. A challenge is identifying these dynamics when you cannot observe them using traditional experimental approaches. Fundamental questions still remain unanswered. What cells are involved? Where do cells come from? Where do cells go? This presentation will highlight the impact of biomimetic model development for making new discoveries about the cellular dynamics involved in adult microvascular network remodelling and the growth of new blood vessels. Novel observations made possible by time-lapse imaging of intact cultured tissues motivate new paradigms related to endothelial cell jumping from one vessel to another, the lineage of vascular pericytes, lymphatic-blood vessel plasticity, and the vasculogenic potential for stem cell populations. Altogether the presentation will serve to frame an appreciation for how new “views” can encourage vascular biologists and physiologists to rethink what we know about angiogenesis.

UNC Bioinformatics Building, Conference Room 1131
130 Mason Farm Rd
Chapel Hill, North Carolina 27514
United States
Map It