The CRI Seminar Series in Collaboration with the CEHS “Context-and Cell Type Specific Genetic Variation Shaping the Human Brain”

Dr. Stein’s lab is exploring how variations in the genome change the structure and development of the brain, and in doing so, create risk for neuropsychiatric illness. They study genetic effects on multiple aspects of the human brain, from macroscale phenotypes like gross human brain structure measured with MRI to molecular phenotypes like gene expression and chromatin accessibility measured with genome-sequencing technologies. The lab uses neural progenitor cells, a modifiable and high-fidelity model system, as well as mouse models to understand how disease-associated variants affect brain development. Read more >>

This seminar is co-sponsored by the Center for Environmental Health and Susceptibility and the Children’s Research Institute. Please contact childrensresearch@med.unc.edu for Zoom details or see flyer for hybrid event attached.