Cancer

The latest cancer news from UNC Health Care and the UNC School of Medicine.

Researchers find genetic precursors of leukemia in patients treated for non-blood cancers

Researchers find genetic precursors of leukemia in patients treated for non-blood cancers

A study led by UNC Lineberger's Catherine Coombs, MD, revealed new risk factors for “clonal hematopoiesis,” a medical phenomenon in which genetic mutations are found in the blood cells of patients who do not have an existing blood cancer.

Researchers find genetic precursors of leukemia in patients treated for non-blood cancers - Read More…

Researchers look to improve detection of skin cancer lacking pigment melanin

Researchers look to improve detection of skin cancer lacking pigment melanin

UNC Lineberger researchers led by Nancy Thomas, MD, PhD, have identified key features linked to amelanotic melanoma, a form of skin cancer that lacks the brown or black color that stems from the pigment melanin.

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Aggressive breast cancers may contribute to racial survival disparities

Aggressive breast cancers may contribute to racial survival disparities

In the Journal of the National Cancer Institute, UNC Lineberger researchers led by Melissa Troester, PhD, published results of an analysis of approximately 1,000 invasive breast tumors. The study confirmed that young black women are more likely to have “triple negative,” or “basal-like,” breast cancers, a subtype that does not express any of the receptors for targeted biologic therapies. The study also identified variation by race within a clinical breast cancer type that has the greatest mortality disparity.

Aggressive breast cancers may contribute to racial survival disparities - Read More…

 Clinical trials framework proposed to bring cancer treatments to sub-Saharan Africa

Clinical trials framework proposed to bring cancer treatments to sub-Saharan Africa

In the journal PLOS Medicine, Satish Gopal, MD, MPH, cancer program director for UNC-Project Malawi, outlined a framework to design studies and bring cancer therapies to sub-Saharan Africa in the absence of clinical trial data specific to the region’s population and health care infrastructure.

Clinical trials framework proposed to bring cancer treatments to sub-Saharan Africa - Read More…

 Using ‘sticky’ nanoparticles, researchers develop new strategy to boost body’s cancer defenses

Using ‘sticky’ nanoparticles, researchers develop new strategy to boost body’s cancer defenses

In the journal Nature Nanotechnology, UNC Lineberger researchers led by Andrew Wang, MD, report on strides made in the development of a strategy to improve the immune system's detection of cancer proteins by using “sticky” nanoparticles.

Using ‘sticky’ nanoparticles, researchers develop new strategy to boost body’s cancer defenses - Read More…

Researchers strive to improve cancer care for older patients

Researchers strive to improve cancer care for older patients

At the 2017 American Society of Clinical Oncology Annual Meeting in Chicago, UNC Lineberger researchers led by Hyman B. Muss, MD, presented preliminary findings from several studies focused on older adults with cancer.

Researchers strive to improve cancer care for older patients - Read More…

UNC Lineberger research featured at ASCO Annual Meeting

UNC Lineberger research featured at ASCO Annual Meeting

Research presented by UNC Lineberger members was featured in plenary and other major sessions of the meeting this year, and was picked up by multiple media outlets.

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Where Cigarette Smoking’s Damage is Done . . . Down to Your DNA

Where Cigarette Smoking’s Damage is Done . . . Down to Your DNA

A new technique from UNC School of Medicine scientists led by Nobel Prize winner Aziz Sancar reveals the genome-wide DNA damage that a major carcinogen causes.

Where Cigarette Smoking’s Damage is Done . . . Down to Your DNA - Read More…

Researchers show how a cancer gene protects genome organization

Researchers show how a cancer gene protects genome organization

UNC study uncovers crucial function of a yeast enzyme Set2 whose well-conserved human counterpart is often mutated in cancers, especially kidney cancer.

Researchers show how a cancer gene protects genome organization - Read More…

Promising results found for treatment of melanoma in the brain

Promising results found for treatment of melanoma in the brain

At the American Society of Clinical Oncology Annual Meeting 2017 in Chicago, researchers presented promising data for two different investigational drug regimens used to treat melanoma that has spread to the brain, a common and deadly complication of this cancer.

Promising results found for treatment of melanoma in the brain - Read More…

New models of kidney cancer may drive immunotherapy research

New models of kidney cancer may drive immunotherapy research

UNC Lineberger member William Y. Kim, MD, and his colleagues report in the journal Nature Communications they have created mouse models of both papillary and clear cell renal cell carcinoma that faithfully mimic the genetic changes seen in tumors of patients with these cancers.

New models of kidney cancer may drive immunotherapy research - Read More…

UNC REX Healthcare presents run/walk to end prostate cancer

UNC REX Healthcare presents run/walk to end prostate cancer

The inaugural Zero – The End of Prostate Cancer run/walk in Raleigh takes place at 7:45 a.m. Saturday, June 24.

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 With ‘new life’ after transplant, cancer survivor renews marriage vows

With ‘new life’ after transplant, cancer survivor renews marriage vows

Recognizing that her husband now had a chance for a new, healthier life thanks to a stem cell transplant, Jackie Hannah secretly arranged for a ceremony for her husband David and her to renew their marriage vows. While he was in the Bone Marrow Transplant Unit in March, just after the transplant, and still dressed in his pajamas, David married Jackie again with hospital staff in attendance.

With ‘new life’ after transplant, cancer survivor renews marriage vows - Read More…

Black, white men view impacts of prostate cancer treatment differently, study finds

Black, white men view impacts of prostate cancer treatment differently, study finds

UNC Lineberger researchers led by Ronald C. Chen surveyed 1,171 men diagnosed with prostate cancer in North Carolina, finding that while both white and black men were concerned about curing their cancer and the quality-of-life impacts of treatment, more black men considered other social and personal factors -- such as recovery time and cost -- to be very important in their treatment decision-making.

Black, white men view impacts of prostate cancer treatment differently, study finds - Read More…

In fruit fly and human genetics, timing is everything

In fruit fly and human genetics, timing is everything

UNC scientists show how DNA is accessed and used during the journey to maturation in fruit flies, and what this might mean to our understanding of how cancers arise.

In fruit fly and human genetics, timing is everything - Read More…

UNC Cancer Survivors Day

UNC Cancer Care is hosting its annual UNC Cancer Survivors Day on Saturday, June 10, 9:30 am - 3 pm. The event is free, though registration is required, and is intended for cancer survivors and their caregivers.

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Study confirms link between alcohol consumption, breast cancer risk in black women

Study confirms link between alcohol consumption, breast cancer risk in black women

In findings published in the journal Cancer, Epidemiology, Biomarkers & Prevention, UNC Lineberger Comprehensive Cancer Center researchers confirmed the link between alcohol consumption and breast cancer risk in a study in black women. The association has been seen in other studies drawn from majority white populations.

Study confirms link between alcohol consumption, breast cancer risk in black women - Read More…

Lineberger researchers speak at N.C. Executive Mansion for Metastatic Breast Cancer Awareness Month proclamation

Lineberger researchers speak at N.C. Executive Mansion for Metastatic Breast Cancer Awareness Month proclamation

Governor Roy Cooper declared April as Metastatic Breast Cancer Awareness Month in North Carolina to bring attention to this second-leading cause of cancer death among women. UNC Lineberger researchers joined First Lady Kristin Cooper at the Executive Mansion Monday at a luncheon hosted by the North Carolina Oncology Navigator Association.

Lineberger researchers speak at N.C. Executive Mansion for Metastatic Breast Cancer Awareness Month proclamation - Read More…

UNC Lineberger researchers to present at AACR Annual Meeting

UNC Lineberger researchers to present at AACR Annual Meeting

The 2017 American Association for Cancer Research Annual Meeting meeting in Washington, D.C., April 1-5, is expected to draw more than 20,000 scientists, clinicians, advocates, and others, including UNC Lineberger faculty, to discuss advances in the field of cancer science.

UNC Lineberger researchers to present at AACR Annual Meeting - Read More…

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