Cancer

The latest cancer news from UNC Health Care and the UNC School of Medicine.

Racial gaps persist in how breast cancer survivors function, feel during treatment and after

Racial gaps persist in how breast cancer survivors function, feel during treatment and after

A UNC Lineberger study published in the journal Breast Cancer Research and Treatment drew upon surveys that assessed health-related quality of life issues for women aged 20 to 74 years who lived in North Carolina and had breast cancer. The analysis was part of the third phase of the Carolina Breast Cancer Study.

Racial gaps persist in how breast cancer survivors function, feel during treatment and after - Read More…

Biology discovery: tight DNA packaging protects against ‘jumping genes,’ potential cellular destruction

Biology discovery: tight DNA packaging protects against ‘jumping genes,’ potential cellular destruction

UNC study indicates that the “heterochromatin” form of DNA packaging mainly guards against virus-like genetic elements that destroy genes and destabilize the genome, a precursor of disease.

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Study finds links between physicians setting cancer care guidelines and drug industry

Study finds links between physicians setting cancer care guidelines and drug industry

UNC Lineberger researchers, led by Aaron Mitchell, MD, found a high prevalence of financial relationships among authors who helped develop a leading set of cancer care guidelines in the United States in a study published in JAMA Oncology. They say the work lays the foundation for future studies of whether the payments influenced clinical practice or guideline recommendations.

Study finds links between physicians setting cancer care guidelines and drug industry - Read More…

Researchers question process for reviewing coverage of ‘off label’ cancer drug use

Researchers question process for reviewing coverage of ‘off label’ cancer drug use

In a paper published online by the Journal of the American Medical Association, UNC Lineberger physician-researchers led by Ethan Basch, MD, MSc, raised concerns that there are inconsistencies between the five reference guides, or compendia, that the Centers for Medicare and Medicaid Services uses to determine which drugs it will reimburse for off-label uses in cancer care.

Researchers question process for reviewing coverage of ‘off label’ cancer drug use - Read More…

Majority of parents support HPV vaccination requirements for school, but only with opt-outs

Majority of parents support HPV vaccination requirements for school, but only with opt-outs

A national survey found that parents were more likely to agree that laws requiring students to be vaccinated against HPV for school entry are a “good idea” when there is an opt-out clause.

Majority of parents support HPV vaccination requirements for school, but only with opt-outs - Read More…

Researchers use genetics to probe immune system’s role in fighting cancer

Researchers use genetics to probe immune system’s role in fighting cancer

Findings published in the Journal of the National Cancer Institute show that immune cells do not respond the same way to all tumor types. The study, led by UNC Lineberger researcher Benjamin Vincent, MD, could lay the foundation for the discovery of biomarkers to determine which patients might respond to certain immune-stimulating cancer treatments.

Researchers use genetics to probe immune system’s role in fighting cancer - Read More…

UNC scientist’s drive for a cancer cure inspired by the father he doesn’t remember

UNC scientist’s drive for a cancer cure inspired by the father he doesn’t remember

Zhen Gu, a biomedical engineer at the University of North Carolina and N.C. State University, is featured in STAT News for his work on cancer.

UNC scientist’s drive for a cancer cure inspired by the father he doesn’t remember - Read More…

The Patient Provider

The Patient Provider

UNC graduate Danielle Harris was just 26 years old when she found out she had acute lymphoblastic leukemia. Her diagnosis forced her to take a break from the Campbell University PA Program. Thanks to her strength and faith, the support of family and friends, and pediatric chemotherapy treatments and her care team at UNC, she's back in school and seeing patients for the first time. The experience, she says, will make her a better provider.

The Patient Provider - Read More…

Insurance, distance to care can be barriers to breast reconstruction

Insurance, distance to care can be barriers to breast reconstruction

Researchers say breast reconstruction can help with self-esteem, sexuality and body image after cancer treatment. But a UNC Lineberger study led by Michelle Roughton, MD, has found that the type of insurance a woman has as well as distance to a plastic surgeon's office can be barriers to the procedure.

Insurance, distance to care can be barriers to breast reconstruction - Read More…

Blood clots and cancer: UNC professor identifies research priorities for National Institutes of Health

Blood clots and cancer: UNC professor identifies research priorities for National Institutes of Health

Nigel Key, director of the UNC Hemophilia and Thrombosis Center, led a national initiative to prioritize research in studying the prevalence and mechanisms of venous thrombosis in cancer patients.

Blood clots and cancer: UNC professor identifies research priorities for National Institutes of Health - Read More…

UNC experts: Doctors shouldn’t routinely recommend e-cigarettes to smokers

UNC experts: Doctors shouldn’t routinely recommend e-cigarettes to smokers

The researchers point out in a commentary published in Annals of Family Medicine that existing treatments are more effective than e-cigarettes to help people quit smoking.

UNC experts: Doctors shouldn’t routinely recommend e-cigarettes to smokers - Read More…

Finding the Next Step

Finding the Next Step

Blossom Damania, PhD, has built her research career tackling difficult questions in cancer and global health research. As she begins her new role as Vice Dean for Research, she’s considering one more: What’s next?

Finding the Next Step - Read More…

Risk of death for adults with blood cancer higher in three N.C. regions

Risk of death for adults with blood cancer higher in three N.C. regions

UNC Lineberger researchers led by Dr. William A. Wood found that for patients treated in a hospital, the risk of death from acute myeloid leukemia was elevated in three regions of the state compared to a benchmark.

Risk of death for adults with blood cancer higher in three N.C. regions - Read More…

Researchers discover how faulty genetic instructions drive a deadly blood cancer in adults

Researchers discover how faulty genetic instructions drive a deadly blood cancer in adults

A study by UNC Lineberger researcher G. Greg Wang, PhD, and colleagues uncovered the genetic mechanism for how acute myeloid leukemia cells with a specific DNA mutation stay as undifferentiated cells, rather than maturing into healthy blood cells.

Researchers discover how faulty genetic instructions drive a deadly blood cancer in adults - Read More…

Cancer patients miss appointments, prescriptions due to inability to afford care

Cancer patients miss appointments, prescriptions due to inability to afford care

More than one-in-four cancer patients had to pay more for medical care than they could afford, according to a study led by UNC Lineberger member Stacie Dusetzina, PhD. A reported 18 percent were unable to afford their prescription medications.

Cancer patients miss appointments, prescriptions due to inability to afford care - Read More…

Bacteria found in female upper reproductive tract, once thought sterile

Bacteria found in female upper reproductive tract, once thought sterile

In a preliminary finding (abstract 5568) presented at the 2016 American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago, UNC Lineberger researchers Wendy Brewster, MD, PhD and Temitope Keku, PhD revealed they have found bacteria in the ovaries and fallopian tubes. Researchers also uncovered a trend toward a distinct bacterial profile in women with ovarian cancer.

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Advanced cancer patients receive aggressive care at high rates at the end of life

Advanced cancer patients receive aggressive care at high rates at the end of life

A national health claims analysis of cancer patients who were younger than age 65 and had metastatic disease revealed that nearly two-thirds were admitted to the hospital or visited the emergency room in the last 30 days of their lives. The UNC Lineberger researchers who led the study also found that nearly a third of patients died in the hospital.

Advanced cancer patients receive aggressive care at high rates at the end of life - Read More…

In all U.S. regions, broad support for increasing legal age of tobacco sales

In all U.S. regions, broad support for increasing legal age of tobacco sales

Researchers from the University of North Carolina at Chapel Hill and East Carolina University report in the American Journal of Preventive Medicine that in all nine regions of the country, a majority of adults supported increasing the minimum legal age for tobacco product sales. They also found the most support for increasing the minimum age to 21 rather than to 20 or 19.

In all U.S. regions, broad support for increasing legal age of tobacco sales - Read More…

 Researchers link gene expression patterns of normal tissue to breast cancer prognosis

Researchers link gene expression patterns of normal tissue to breast cancer prognosis

In the journal npj Breast Cancer, researchers reported they identified a particular gene expression pattern in normal-appearing breast tissue around tumors that was linked to lower 10-year survival rates for women with estrogen receptor-positive breast cancer.

Researchers link gene expression patterns of normal tissue to breast cancer prognosis - Read More…

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