Cancer

The latest cancer news from UNC Health Care and the UNC School of Medicine.

The Battle against Microscopic Bugs

The Battle against Microscopic Bugs

Edward Miao, MD, PhD, earns a Jefferson-Pilot Award for his groundbreaking work on the interplay between dangerous pathogens and the human immune response.

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On Auto Attack

On Auto Attack

Our own immune cells can destroy other healthy cells to cause severe and chronic diseases. Maureen Su, MD, a 2014 Jefferson-Pilot award winner, studies how this autoimmunity happens and what it might tell us about potential cancer therapies.

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UNC researchers silence leading cancer-causing gene

UNC researchers silence leading cancer-causing gene

A novel siRNA-based molecule, developed by Chad Pecot, MD, successfully targets KRAS, a well-studied but hard to halt protein important for cancer development and metastasis.

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Partnerships, cancer research in Malawi to expand with new grant

Partnerships, cancer research in Malawi to expand with new grant

UNC Lineberger Comprehensive Cancer Center and the UNC Institute for Global Health & Infectious Diseases have received a $3.7 million grant from the National Cancer Institute (NCI) to study the growing worldwide cancer problem and expand the University’s efforts in Malawi to study and treat HIV-associated cancers.

Partnerships, cancer research in Malawi to expand with new grant - Read More…

UNC scientists discover hidden subpopulation of melanoma cells

UNC scientists discover hidden subpopulation of melanoma cells

The research, led by Andrew C. Dudley, PhD, has implications for developing cancer drugs that target blood vessels that feed tumors.

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Researchers create DNA-based ‘nano-cocoons’ to attack and kill cancer cells

Researchers create DNA-based ‘nano-cocoons’ to attack and kill cancer cells

In cell lines, scientists at the joint UNC-NC State biomedical engineering program have shown that the new nano particles can stealthily enter cancer cells and release a known drug to attack tumors from the inside.

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All the Cell’s a Stage

All the Cell’s a Stage

Brian Strahl, PhD, and his band of biochemists unravel the complicated mysteries of the epigenetic code to find a culprit in cancer development.

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UNC researchers receive $2.85-million NIH BRAIN Initiative grant

UNC researchers receive $2.85-million NIH BRAIN Initiative grant

Led by Bryan L. Roth, MD, PhD, three UNC labs will develop the next generation neuroscience tool-kit to accelerate novel treatments for neuropsychiatric and a host of other diseases.

UNC researchers receive $2.85-million NIH BRAIN Initiative grant - Read More…

How a Father’s Illness Ages One for Good

How a Father’s Illness Ages One for Good

Jordan Sanderson, a 25-year-old Carteret County native and current Nash County resident, shares how her father’s diagnosis and treatment challenged her and aged her in a good way.

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The Geneticist

The Geneticist

With his selection to the NIH Council of Councils, Terry Magnuson, PhD, becomes the first UNC scientist appointed to the board dedicated to funding the biggest ideas in medical research.

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UNC researchers find final pieces to the circadian clock puzzle

UNC researchers find final pieces to the circadian clock puzzle

Sixteen years after scientists found the genes that control the circadian clock in all cells, the lab of UNC’s Aziz Sancar, MD, PhD, discovered the mechanisms responsible for keeping the clock in sync.

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UNC researchers find new genetic target for a different kind of cancer drug

UNC researchers find new genetic target for a different kind of cancer drug

Upstream of the proteins that cancer cells use to proliferate sits RBM4, a gene-splicing protein that UNC researcher Zefeng Wang, PhD, discovered is drastically reduced in human lung and breast cancer cells.

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Popular cancer drug target implicated in cardiovascular defects

Popular cancer drug target implicated in cardiovascular defects

Research led by UNC’s Kathleen Caron, PhD, shows that halting the protein CXCR7 leads to over activation of adrenomedullin, a hormone needed at proper levels for normal cardiovascular development

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The Ras Tracker

The Ras Tracker

For more than 20 years, Sharon Campbell, PhD, has been studying Ras, a protein implicated in 30 percent of all cancers. Now she’s on the hunt for alternative ways to shut the protein down.

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 Largest cancer genetic analysis reveals new way of classifying cancer

Largest cancer genetic analysis reveals new way of classifying cancer

The work, led by researchers at the UNC Lineberger Comprehensive Cancer Center, UNC-Chapel Hill and other TCGA sites, revamps traditional ideas of how cancers are diagnosed and treated and could also have a profound impact on the future landscape of drug development.

Largest cancer genetic analysis reveals new way of classifying cancer - Read More…

The Signal and the Noise

The Signal and the Noise

Henrik Dohlman, PhD, discovered why seemingly identical cells might react differently to the chemical signals inside our bodies and the drugs we use to battle diseases.

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Dudley named American Cancer Society Research Scholar

Dudley named American Cancer Society Research Scholar

Andrew Dudley, PhD, assistant professor of cell biology and physiology, was recently named an American Cancer Society Research Scholar. His funded research proposal will investigate “Mechanisms of tumor escape from anti-angiogenic therapy.”

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Wang recieves grant from Gabrielle's Angel Foundation for Cancer Research

Wang recieves grant from Gabrielle's Angel Foundation for Cancer Research

Greg Wang, PhD, assistant professor of biochemistry and biophysics, received a grant to study "Novel Approaches to Target PRC2 Enzymatic Complexes for the Treatment of Hematopoietic Malignancies."

Wang recieves grant from Gabrielle's Angel Foundation for Cancer Research - Read More…

Doctors not adequately informing patients of cancer screening pros and cons, study finds

Doctors not adequately informing patients of cancer screening pros and cons, study finds

Though cancer screening has come a long way, physicians still do not thoroughly discuss with patients the advantages and disadvantages of these procedures before decisions are made to undergo the screenings, according to a new study co-authored by a UNC physician.

Doctors not adequately informing patients of cancer screening pros and cons, study finds - Read More…

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