Cancer

The latest cancer news from UNC Health Care and the UNC School of Medicine.

Scientists zero in on ways to boost colorectal cancer screening

Scientists zero in on ways to boost colorectal cancer screening

UNC Lineberger's Daniel Reuland, MD, MPH, and colleagues published in JAMA Internal Medicine a review of data from 73 randomized clinical trials that tested different ways of increasing screening for colorectal cancer. Their analysis identified three approaches as being the most effective.

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UNC to Create the Next Generation, Ultra-Long-Acting Antiretroviral Formulations for HIV Treatment and Prevention

UNC to Create the Next Generation, Ultra-Long-Acting Antiretroviral Formulations for HIV Treatment and Prevention

New project aims to provide long-lasting HIV treatment and/or protection from a single injection. Angela Wahl, PhD, Rahima Benhabbour, PhD, and Martina Kovarova, PhD, are collaborating to lead the work, which is funded by a $3.8-million NIH grant.

UNC to Create the Next Generation, Ultra-Long-Acting Antiretroviral Formulations for HIV Treatment and Prevention - Read More…

Fast Break raises funds, awareness for cancer research

Fast Break raises funds, awareness for cancer research

The 14th annual Roy Williams’ Fast Break Against Cancer on Tuesday has raised $209,462 to date, and the total will increase after an online auction concludes on Oct. 12. The event has brought in more than $2.7 million since 2005.

Fast Break raises funds, awareness for cancer research - Read More…

Susan G. Komen awards UNC Lineberger $1.1M for breast cancer research

Susan G. Komen awards UNC Lineberger $1.1M for breast cancer research

Included in the new investments by Susan G. Komen was $400,000 for UNC Lineberger’s Lisa Carey, MD, the physician-in-chief of the N.C. Cancer Hospital, Richardson and Marilyn Jacobs Preyer Distinguished Professor in Breast Cancer Research, chief of the UNC School of Medicine Division of Hematology/Oncology, and a member of the Komen Scientific Advisory Board, for a study of HER2-positive breast cancer.

Susan G. Komen awards UNC Lineberger $1.1M for breast cancer research - Read More…

Study focused on improving radiation treatment for cancers in pet dogs

Study focused on improving radiation treatment for cancers in pet dogs

UNC Lineberger's Paul A. Dayton, PhD, and his colleagues have been awarded a five-year, $3.2 million grant from the National Cancer Institute to investigate how to improve radiation treatment for pet dogs undergoing treatment for sarcoma.

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Retreat highlights postdoctoral fellows’ research

Retreat highlights postdoctoral fellows’ research

UNC Lineberger's 43rd Annual Postdoc-Faculty Research Day was held Tuesday at the Carolina Club.

Retreat highlights postdoctoral fellows’ research - Read More…

Breaking the link between obesity, gastrointestinal cancers

Breaking the link between obesity, gastrointestinal cancers

In an article in the journal Nature Reviews Gastroenterology & Hepatology, UNC Lineberger’s Stephen Hursting, PhD, MPH, and his colleagues reviewed findings from research looking at the biological links between obesity and cancers of the colon, rectum, pancreas, liver, esophagus, gallbladder and stomach, as well as published studies on how diet, exercise, weight loss surgery, and other weight-related interventions may help reverse this connection.

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UNC Researchers Awarded Emerging Challenges Grants

UNC Researchers Awarded Emerging Challenges Grants

UNC School of Medicine, UNC Medical Center, and NC TraCS Institute awarded $50,000 to two teams of researchers led by Jill Bates, PharmD, Alison Stuebe, MD, and Ana Whitney, MS, to study pharmacogenomics and social determinants of maternal health.

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Anti-inflammatory Protein Promotes Healthy Gut Bacteria to Curb Obesity

Anti-inflammatory Protein Promotes Healthy Gut Bacteria to Curb Obesity

UNC School of Medicine researchers led by Jenny Ting, PhD, and colleagues, publish a new approach to weight loss and diabetes prevention.

Anti-inflammatory Protein Promotes Healthy Gut Bacteria to Curb Obesity - Read More…

Findings could improve treatment for challenging acute leukemia in children

Findings could improve treatment for challenging acute leukemia in children

There is no consensus on the best way to treat mixed phenotype acute leukemia, a rare blood cancer with survival rates of between 47 and 75 percent for children. Researchers from St. Jude Children’s Research Hospital and the University of North Carolina Lineberger Comprehensive Cancer Center, led by Thomas Alexander, MD, MPH, have made important discoveries about the genetics of this disease that could lead to better treatments.

Findings could improve treatment for challenging acute leukemia in children - Read More…

Scientists Create Method to Map Vast Unknown Territory of Long Non-coding RNA

Scientists Create Method to Map Vast Unknown Territory of Long Non-coding RNA

UNC School of Medicine researchers led by Mauro Calabrese, PhD, have developed a way to categorize mysterious RNA molecules by their likely function, a big first step toward quickening the discovery of their roles in human health and diseases, such as cancers.

Scientists Create Method to Map Vast Unknown Territory of Long Non-coding RNA - Read More…

Genomic study finds a new role for microRNAs as predictors of Crohn’s disease progression

Genomic study finds a new role for microRNAs as predictors of Crohn’s disease progression

These findings by UNC School of Medicine researchers are an important step forward in designing more effective clinical trials and developing personalized Crohn’s disease therapies.

Genomic study finds a new role for microRNAs as predictors of Crohn’s disease progression - Read More…

Johnson Honored with Battle Distinguished Cancer Research Award

Johnson Honored with Battle Distinguished Cancer Research Award

Gary Johnson, PhD, the Kenan Distinguished Professor in the UNC School of Medicine Department of Pharmacology, and co-director of UNC Lineberger’s Molecular Therapeutics Program was awarded the 2017-2018 Hyman L. Battle Distinguished Cancer Research Award.

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Smith awarded $8.5 million to compare treatments for recurrent bladder cancer

Smith awarded $8.5 million to compare treatments for recurrent bladder cancer

UNC Lineberger’s Angela B. Smith, MD, MS, an associate professor in the UNC School of Medicine Department of Urology and director of urologic oncology, and her collaborators were awarded a contract from the Patient-Centered Outcomes Research Institute to compare bladder removal with medical therapy in bladder cancer patients.

Smith awarded $8.5 million to compare treatments for recurrent bladder cancer - Read More…

For her father, Morgan runs to support cancer research

For her father, Morgan runs to support cancer research

Katie Morgan, PharmD, a clinical pharmacist working with neuro-oncology and genitourinary-oncology patients at the N.C. Cancer Hospital, found her calling during her father's four-year battle with glioblastoma. To honor him and others fighting brain cancer, Morgan is running in the Head for the Cure 5K, which will be held Sept. 8 in Chapel Hill to raise money for brain cancer research.

For her father, Morgan runs to support cancer research - Read More…

Researchers lay the foundation for personalized immune treatments for leukemia

Researchers lay the foundation for personalized immune treatments for leukemia

In the journal Blood Advances, UNC Lineberger’s Ben Vincent, MD, Paul Armistead, MD, PhD, and their collaborators reported early findings from a new study that could aid in the development of immune-based treatments tailored to individual leukemia patients undergoing stem cell transplantation.

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 Stem cells show promise as drug delivery tool for childhood brain cancer

Stem cells show promise as drug delivery tool for childhood brain cancer

UNC Lineberger’s Shawn Hingtgen, PhD, and his collaborators including Scott Elton, MD, showed they could shrink tumors in laboratory models of medulloblastoma and extend life. Results of this PLOS ONE study provide a necessary step toward developing clinical trials for children.

Stem cells show promise as drug delivery tool for childhood brain cancer - Read More…

Scientists Discover Intricacies of Serotonin Receptor Crucial for Better Therapeutics

Scientists Discover Intricacies of Serotonin Receptor Crucial for Better Therapeutics

By crystalizing a serotonin receptor bound to several common compounds, UNC School of Medicine scientists led by Bryan L. Roth discovered how slightly different drugs can cause severe side effects or none at all. The findings should accelerate the design of safer and more effective medications for a variety of conditions.

Scientists Discover Intricacies of Serotonin Receptor Crucial for Better Therapeutics - Read More…

Brown earns MIRA from NIH

Brown earns MIRA from NIH

The National Institute of General Medical Sciences awarded Nicholas G. Brown $1.25 million over five years for research aimed at investigating the regulation of the enzyme known as the Anaphase-Promoting Complex/Cyclosome (APC/C) to ultimately understand cell cycle progression.

Brown earns MIRA from NIH - Read More…

Researchers Reveal Miscarriage Cause, Key Cellular Targets of Potential Drugs

Researchers Reveal Miscarriage Cause, Key Cellular Targets of Potential Drugs

UNC School of Medicine researchers show how a rare gene defect disrupts an important interaction between proteins, including cellular receptors crucial to cell function and human health.

Researchers Reveal Miscarriage Cause, Key Cellular Targets of Potential Drugs - Read More…

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