Cancer

The latest cancer news from UNC Health Care and the UNC School of Medicine.

UNC Lineberger-led study builds understanding of hepatitis C virus replication

UNC Lineberger-led study builds understanding of hepatitis C virus replication

Hepatitis C virus infection is a common cause of liver disease and of liver cancer in the United States. Through a new study that explores one aspect of how the virus hijacks host cell machinery to replicate itself, UNC Lineberger Comprehensive Cancer Center researchers have gained insight into the workings of a potential drug target for hepatitis C.

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Cancer Survivor Becomes Ambassador for Hope

Cancer Survivor Becomes Ambassador for Hope

The latest installment in our Real Medicine video series features one of our Patient Ambassadors for North Carolina Children's Hospital.

Cancer Survivor Becomes Ambassador for Hope - Read More…

Epigenetic Breakthrough: A first of its kind tool to study the histone code

Epigenetic Breakthrough: A first of its kind tool to study the histone code

Scientists from UNC-Chapel Hill have created a new way to investigate epigenetic mechanisms important in diseases ranging from Alzheimer’s to cancers.

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Potential pancreatic cancer treatment could increase life expectancy

Potential pancreatic cancer treatment could increase life expectancy

Device that drives drugs into solid tumors that are poorly vascularized opens the possibility of life-saving surgeries in cancer patients. James Byrne, PhD, a medical student and member of Joseph DeSimone’s lab, led the research by constructing the device and examining its ability to deliver chemotherapeutic drugs effectively to pancreatic cancer tumors, as well as two types of breast cancer tumors.

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UNC researcher co-leads effort to map genomic changes in head and neck cancer

UNC researcher co-leads effort to map genomic changes in head and neck cancer

A study co-led by a UNC Lineberger Comprehensive Cancer Center researcher has identified genomic changes in head and neck cancers linked to the sexually transmitted disease HPV -- the latest finding of a collaborative scientific effort designed to map out the genomic changes driving cancer.

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Researchers pinpoint two genes that trigger severest form of ovarian cancer

Researchers pinpoint two genes that trigger severest form of ovarian cancer

UNC geneticists led by Terry Magnuson, PhD, and Ron Chandler, PhD, create the first mouse model of ovarian clear cell carcinoma; show how a known drug can suppress tumor growth.

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Statewide network established to support cancer survivors

Statewide network established to support cancer survivors

The Duke Endowment awards $461,750 grant to UNC Lineberger’s Comprehensive Cancer Support Program.

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Parsing the Pathways

Parsing the Pathways

Graduate student Kathleen Mulvaney investigates the newly discovered interplay between two of the proteins that allow cells to divide.

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‘Flying carpet’ technique delivers one-two punch of anticancer drugs

‘Flying carpet’ technique delivers one-two punch of anticancer drugs

Researchers in the joint UNC-NCSU biomedical engineering department have used nanoscale graphene to improve upon traditional delivery of two cancer drugs.

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Priceless Gem

Priceless Gem

Carolina legend Danny Talbott performed at the highest level on both the football field and baseball diamond during his years as a Tar Heel. Since 2010, he’s been back in Chapel Hill, battling the toughest opponent he’s faced: multiple myeloma. He can’t imagine going anywhere else to do it.

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UNC researchers pinpoint chemo effect on brain cells, potential link to autism

UNC researchers pinpoint chemo effect on brain cells, potential link to autism

The common chemotherapy drug topotecan disrupts a gene integral for neuron communication, though the effects are reversible. The research also homes in on an underlying cause of autism.

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The Battle against Microscopic Bugs

The Battle against Microscopic Bugs

Edward Miao, MD, PhD, earns a Jefferson-Pilot Award for his groundbreaking work on the interplay between dangerous pathogens and the human immune response.

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On Auto Attack

On Auto Attack

Our own immune cells can destroy other healthy cells to cause severe and chronic diseases. Maureen Su, MD, a 2014 Jefferson-Pilot award winner, studies how this autoimmunity happens and what it might tell us about potential cancer therapies.

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UNC researchers silence leading cancer-causing gene

UNC researchers silence leading cancer-causing gene

A novel siRNA-based molecule, developed by Chad Pecot, MD, successfully targets KRAS, a well-studied but hard to halt protein important for cancer development and metastasis.

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Partnerships, cancer research in Malawi to expand with new grant

Partnerships, cancer research in Malawi to expand with new grant

UNC Lineberger Comprehensive Cancer Center and the UNC Institute for Global Health & Infectious Diseases have received a $3.7 million grant from the National Cancer Institute (NCI) to study the growing worldwide cancer problem and expand the University’s efforts in Malawi to study and treat HIV-associated cancers.

Partnerships, cancer research in Malawi to expand with new grant - Read More…

UNC scientists discover hidden subpopulation of melanoma cells

UNC scientists discover hidden subpopulation of melanoma cells

The research, led by Andrew C. Dudley, PhD, has implications for developing cancer drugs that target blood vessels that feed tumors.

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Researchers create DNA-based ‘nano-cocoons’ to attack and kill cancer cells

Researchers create DNA-based ‘nano-cocoons’ to attack and kill cancer cells

In cell lines, scientists at the joint UNC-NC State biomedical engineering program have shown that the new nano particles can stealthily enter cancer cells and release a known drug to attack tumors from the inside.

Researchers create DNA-based ‘nano-cocoons’ to attack and kill cancer cells - Read More…

All the Cell’s a Stage

All the Cell’s a Stage

Brian Strahl, PhD, and his band of biochemists unravel the complicated mysteries of the epigenetic code to find a culprit in cancer development.

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UNC researchers receive $2.85-million NIH BRAIN Initiative grant

UNC researchers receive $2.85-million NIH BRAIN Initiative grant

Led by Bryan L. Roth, MD, PhD, three UNC labs will develop the next generation neuroscience tool-kit to accelerate novel treatments for neuropsychiatric and a host of other diseases.

UNC researchers receive $2.85-million NIH BRAIN Initiative grant - Read More…

How a Father’s Illness Ages One for Good

How a Father’s Illness Ages One for Good

Jordan Sanderson, a 25-year-old Carteret County native and current Nash County resident, shares how her father’s diagnosis and treatment challenged her and aged her in a good way.

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