Cancer

The latest cancer news from UNC Health Care and the UNC School of Medicine.

UNC Scientists Discover Proteins Keeping Stem Cells in their Undifferentiated State

UNC Scientists Discover Proteins Keeping Stem Cells in their Undifferentiated State

The lab of Jean Cook, PhD, found how a chain of proteins called an MCM complex could enable the fast cell-division that makes some forms of cancer so dangerous.

UNC Scientists Discover Proteins Keeping Stem Cells in their Undifferentiated State - Read More…

Immunotherapy Could Be Beneficial for Relapsed Acute Myeloid Leukemia

Immunotherapy Could Be Beneficial for Relapsed Acute Myeloid Leukemia

Researchers led by UNC Lineberger's Joshua Zeidner, MD, presented preliminary results from an ongoing phase II trial of the checkpoint inhibitor pembrolizumab and chemotherapy for relaposed or refractory acute myeloid leukemia at the 59th American Society of Hematology Annual Meeting in Atlanta.

Immunotherapy Could Be Beneficial for Relapsed Acute Myeloid Leukemia - Read More…

Using Software, Researchers Predict Tumor Markers That Could Be Immune Targets

Using Software, Researchers Predict Tumor Markers That Could Be Immune Targets

UNC Lineberger researchers led by Benjamin Vincent, MD, reported preliminary findings at the 59th ASH Annual Meeting in Atlanta that are an early step in the overall plan to use the software’s predictions to develop immune-based therapies for leukemia.

Using Software, Researchers Predict Tumor Markers That Could Be Immune Targets - Read More…

Biological Factors Don't Completely Explain Racial Disparities for ‘Good Prognosis’ Breast Cancer

Biological Factors Don't Completely Explain Racial Disparities for ‘Good Prognosis’ Breast Cancer

The biological features of patients’ tumors partially explained a racial disparity for women with hormone receptor-positive, HER2-negative breast cancer, but UNC Lineberger researchers led by Katherine Reeder-Hayes, MD, MBA, MSc, said it didn’t explain it completely. The preliminary findings were reported at the 2017 San Antonio Breast Cancer Symposium.

Biological Factors Don't Completely Explain Racial Disparities for ‘Good Prognosis’ Breast Cancer - Read More…

NCI Grant to Help More Cancer Patients Become Tobacco-Free

NCI Grant to Help More Cancer Patients Become Tobacco-Free

A grant from the National Cancer Institute will help expand tobacco cessation programs for cancer patients at the N.C. Cancer Hospital. Adam O. Goldstein, MD, MPH, will lead the effort.

NCI Grant to Help More Cancer Patients Become Tobacco-Free - Read More…

Pairing cancer genomics with cognitive computing highlights potential therapeutic options

Pairing cancer genomics with cognitive computing highlights potential therapeutic options

Study findings suggest that cognitive computing could help physicians to stay abreast of an ever-expanding body of scientific literature as well as highlight potential cancer therapeutic options. UNC Lineberger's William Kim, MD, is the study's corresponding author.

Pairing cancer genomics with cognitive computing highlights potential therapeutic options - Read More…

The Leukemia & Lymphoma Society awards grant to Savoldo for immunotherapy research

The Leukemia & Lymphoma Society awards grant to Savoldo for immunotherapy research

A grant from The Leukemia & Lymphoma Society will help fund clinical research led by UNC Lineberger's Barbara Savoldo, MD, PhD, into an investigational chimeric antigen receptor (CAR) T-cell treatment for acute lymphoblastic leukemia that would include a built-in "safety switch."

The Leukemia & Lymphoma Society awards grant to Savoldo for immunotherapy research - Read More…

UNC School of Medicine Professors Elected as AAAS Fellows

UNC School of Medicine Professors Elected as AAAS Fellows

Blossom Damania and Mark Zylka have been recognized by the world’s largest general scientific society for their contributions to the fields of biological and medical sciences.

UNC School of Medicine Professors Elected as AAAS Fellows - Read More…

Gopal to be Winter Commencement speaker

Gopal to be Winter Commencement speaker

Dr. Satish Gopal, an innovative cancer researcher on the forefront of cancer treatment in Malawi, will be the featured speaker at UNC's Winter Commencement ceremony.

Gopal to be Winter Commencement speaker - Read More…

Timing could matter to how responsive cancer cells are to treatment, study suggests

Timing could matter to how responsive cancer cells are to treatment, study suggests

In a new study published in Cell Systems, UNC Lineberger's Jeremy Purvis, PhD, and colleagues report that the timing of when DNA damage occurs within these different checkpoints matters to a cell’s fate.

Timing could matter to how responsive cancer cells are to treatment, study suggests - Read More…

Delays for melanoma surgeries linked to insurance type

Delays for melanoma surgeries linked to insurance type

Researchers report in JAMA Dermatology that surgical treatment delays – defined as surgery that occurred more than six weeks after diagnosis – were common. Medicaid patients were 36 percent more likely than private insurance patients to experience delays.

Delays for melanoma surgeries linked to insurance type - Read More…

Blood test for HPV may help predict risk in cancer patients

Blood test for HPV may help predict risk in cancer patients

Preliminary findings from a study led by UNC Lineberger's Bhisham Chera, MD, and Gaorav Gupta, MD, PhD, suggest a genetic test for HPV16 in blood could be useful to help assess risk for patients and identify patients suitable for lower treatment doses.

Blood test for HPV may help predict risk in cancer patients - Read More…

Roy Williams' Fast Break Against Cancer tops $2.4 million

Roy Williams' Fast Break Against Cancer tops $2.4 million

On Oct. 2, North Carolina men's basketball coach Roy Williams hosted his 13th annual Fast Break Against Cancer breakfast and auction to support cancer research at the UNC Lineberger Comprehensive Cancer Center.

Roy Williams' Fast Break Against Cancer tops $2.4 million - Read More…

Can T cells be unleashed to attack skin tumors?

Can T cells be unleashed to attack skin tumors?

Maureen Su, MD, and colleagues report on a potential new way to fight melanoma by blocking one of the immune system’s checks and balances, thus freeing immune cells to attack tumors and kill cancer cells.

Can T cells be unleashed to attack skin tumors? - Read More…

How do cancer cells release their “brakes” to allow division?

How do cancer cells release their “brakes” to allow division?

Research led by Michael J. Emanuele, PhD, details a specific cellular pathway that allows replication and division – key information in the search for better ways to halt tumor growth.

How do cancer cells release their “brakes” to allow division? - Read More…

Savings less than expected for generic oral chemotherapy

Savings less than expected for generic oral chemotherapy

A study led by UNC Lineberger's Stacie Dusetzina, PhD, compared the cost of the generic and brand-name version of capecitabine, which was one of the first high-priced chemotherapy pills to come off patent in the United States. Their findings offer a glimpse into what could be happening with generic competition in this specialty drug market.

Savings less than expected for generic oral chemotherapy - Read More…

From the Ground Up: The State of Cancer Care in Malawi

From the Ground Up: The State of Cancer Care in Malawi

Satish Gopal, MD, head of UNC’s cancer care efforts at UNC-Project Malawi, will welcome collaborators from across the region for the Malawi Cancer Care Symposium on Aug. 28 and 29.

From the Ground Up: The State of Cancer Care in Malawi - Read More…

Researchers find genetic precursors of leukemia in patients treated for non-blood cancers

Researchers find genetic precursors of leukemia in patients treated for non-blood cancers

A study led by UNC Lineberger's Catherine Coombs, MD, revealed new risk factors for “clonal hematopoiesis,” a medical phenomenon in which genetic mutations are found in the blood cells of patients who do not have an existing blood cancer.

Researchers find genetic precursors of leukemia in patients treated for non-blood cancers - Read More…

Researchers look to improve detection of skin cancer lacking pigment melanin

Researchers look to improve detection of skin cancer lacking pigment melanin

UNC Lineberger researchers led by Nancy Thomas, MD, PhD, have identified key features linked to amelanotic melanoma, a form of skin cancer that lacks the brown or black color that stems from the pigment melanin.

Researchers look to improve detection of skin cancer lacking pigment melanin - Read More…

Aggressive breast cancers may contribute to racial survival disparities

Aggressive breast cancers may contribute to racial survival disparities

In the Journal of the National Cancer Institute, UNC Lineberger researchers led by Melissa Troester, PhD, published results of an analysis of approximately 1,000 invasive breast tumors. The study confirmed that young black women are more likely to have “triple negative,” or “basal-like,” breast cancers, a subtype that does not express any of the receptors for targeted biologic therapies. The study also identified variation by race within a clinical breast cancer type that has the greatest mortality disparity.

Aggressive breast cancers may contribute to racial survival disparities - Read More…

Share This: