Cancer

The latest cancer news from UNC Health Care and the UNC School of Medicine.

Brown earns MIRA from NIH

Brown earns MIRA from NIH

The National Institute of General Medical Sciences awarded Nicholas G. Brown $1.25 million over five years for research aimed at investigating the regulation of the enzyme known as the Anaphase-Promoting Complex/Cyclosome (APC/C) to ultimately understand cell cycle progression.

Brown earns MIRA from NIH - Read More…

Researchers Reveal Miscarriage Cause, Key Cellular Targets of Potential Drugs

Researchers Reveal Miscarriage Cause, Key Cellular Targets of Potential Drugs

UNC School of Medicine researchers show how a rare gene defect disrupts an important interaction between proteins, including cellular receptors crucial to cell function and human health.

Researchers Reveal Miscarriage Cause, Key Cellular Targets of Potential Drugs - Read More…

Doctor-patient discussions neglect potential harms of lung cancer screening, study finds

Doctor-patient discussions neglect potential harms of lung cancer screening, study finds

UNC Lineberger researchers led by Daniel Reuland, MD, MPH, report in JAMA Internal Medicine that their analysis of 14 audio-recorded office visit discussions between doctors and patients found the quality of the conversation about lung cancer screening was “poor” and discussion of the potential harms of screening was “virtually nonexistent.” In addition, the doctors spent less than a minute, on average, discussing the issue.

Doctor-patient discussions neglect potential harms of lung cancer screening, study finds - Read More…

 Researchers find potential key to unlocking the immune system in pancreatic cancer

Researchers find potential key to unlocking the immune system in pancreatic cancer

In the journal Cancer Immunology Research, scientists led by UNC Lineberger's Yuliya Pylayeva-Gupta, PhD, revealed that a molecule called interleukin-35 plays a role in suppressing cancer-fighting immune cells in pancreatic cancer.

Researchers find potential key to unlocking the immune system in pancreatic cancer - Read More…

Pecot featured in story about becoming a doctor and researcher

Pecot featured in story about becoming a doctor and researcher

UNC Lineberger oncologist and cancer researcher Chad Pecot, MD, who was diagnosed with cancer at age 20, now works to stop the spread of lung cancer.

Pecot featured in story about becoming a doctor and researcher - Read More…

 Discovery of kidney cancer driver could lead to new treatment strategy

Discovery of kidney cancer driver could lead to new treatment strategy

In a study published in the journal Science, researchers led by UNC Lineberger's Qing Zhang, PhD, suggest that ZHX2 is a potential new therapeutic target for clear cell renal cell carcinoma, which is the most common type of kidney cancer.

Discovery of kidney cancer driver could lead to new treatment strategy - Read More…

Buy your tickets to Be Loud! 2018, a concert to support AYA cancer program at UNC Lineberger

Buy your tickets to Be Loud! 2018, a concert to support AYA cancer program at UNC Lineberger

The Be Loud! Sophie Foundation will hold its annual concert weekend fundraiser at Cat's Cradle August 24 and 25. Tickets are now available. ALL proceeds fund the AYA Cancer Support Program at the UNC Lineberger Comprehensive Cancer Center.

Buy your tickets to Be Loud! 2018, a concert to support AYA cancer program at UNC Lineberger - Read More…

UNC School of Medicine graduate students earn prestigious HHMI Gilliam Fellowships

UNC School of Medicine graduate students earn prestigious HHMI Gilliam Fellowships

Megan Agajanian, in the lab of Ben Major, PhD, and Juanita Limas, in the lab of Jean Cook, PhD, will receive up to $150,000 each to support their biomedical research at the UNC School of Medicine and the UNC Lineberger Comprehensive Cancer Center.

UNC School of Medicine graduate students earn prestigious HHMI Gilliam Fellowships - Read More…

By sending tests in the mail, researchers boost colorectal cancer screening

By sending tests in the mail, researchers boost colorectal cancer screening

Alison Brenner, PhD, MPH, and Stephanie Wheeler, PhD, MPH, researchers with UNC Lineberger’s Carolina Cancer Screening Initiative, in collaboration with the Mecklenburg County Health Department in Charlotte, examined the impact of targeted outreach to more than 2,100 people insured by Medicaid who were not up-to-date with colorectal cancer screening.

By sending tests in the mail, researchers boost colorectal cancer screening - Read More…

 Researchers clarify role of mutations in glioblastoma

Researchers clarify role of mutations in glioblastoma

In a preclinical study, researchers led by UNC Lineberger's Ryan Miller, MD, PhD, investigated whether the location of where the mutation occurred within the sequence of the PIK3CA gene affected the mutation’s ability to help drive cancerous growth. They also evaluated whether the location of the mutation would affect the cancer's response to certain treatments.

Researchers clarify role of mutations in glioblastoma - Read More…

 UNC Lineberger, King's College London scientists collaborate to accelerate cancer research

UNC Lineberger, King's College London scientists collaborate to accelerate cancer research

Across two days in June, scientists held sessions on breast cancer and immunotherapy research, with a focus on identifying cooperative initiatives and funding opportunities.

UNC Lineberger, King's College London scientists collaborate to accelerate cancer research - Read More…

UNC School of Medicine Celebrates Third Annual Class of Yang Family Biomedical Scholars

UNC School of Medicine Celebrates Third Annual Class of Yang Family Biomedical Scholars

The award, which recognizes the research achievements of young tenured faculty, is made possible through a generous donation from Lenovo chairman and CEO Yuanqing Yang with additional financial support from Mr. To Hing Wu. This year’s recipients are Yen-Yu Ian Shih, Louise Henderson, and Jon Juliano.

UNC School of Medicine Celebrates Third Annual Class of Yang Family Biomedical Scholars - Read More…

Kuhlman wins DeLano Award for computer applications to enhance research

Kuhlman wins DeLano Award for computer applications to enhance research

The American Society for Biochemistry and Molecular Biology issued 12 awards to top scientists, including Brian Kuhlman, PhD, professor of biochemistry and biophysics.

Kuhlman wins DeLano Award for computer applications to enhance research - Read More…

 UNC Lineberger hosts Malawi delegation

UNC Lineberger hosts Malawi delegation

A team of Malawian health and government officials met with UNC health and university leaders, researchers and clinical staff across three days to prepare for the opening of the first dedicated cancer center in Malawi.

UNC Lineberger hosts Malawi delegation - Read More…

Higher body fat linked to lower breast cancer risk in younger women

Higher body fat linked to lower breast cancer risk in younger women

An analysis co-led led by UNC Lineberger's Hazel B. Nichols, PhD, linked higher body mass index to lower breast cancer risk for younger women, even for women within a normal weight range.

Higher body fat linked to lower breast cancer risk in younger women - Read More…

Scientists discover new gene expression mechanism with possible role in human disease

Scientists discover new gene expression mechanism with possible role in human disease

UNC School of Medicine researchers, led by Brian Strahl, PhD, found surprising role for a protein called Spt6, which is crucial to the maintenance of proper messenger RNA levels in cells, a discovery that opens new research avenues and suggests a target for basic understanding, diagnosis, and treatment of human diseases.

Scientists discover new gene expression mechanism with possible role in human disease - Read More…

Parents ranked cancer prevention as No. 1 provider reason for HPV vaccination

Parents ranked cancer prevention as No. 1 provider reason for HPV vaccination

A survey led by UNC Lineberger's Melissa Gilkey, PhD, and collaborators found that parents ranked cancer prevention as the most compelling reason health care providers can give for recommending the human papillomavirus (HPV) vaccine.

Parents ranked cancer prevention as No. 1 provider reason for HPV vaccination - Read More…

UNC Lineberger among national leaders endorsing goal of eliminating HPV-related cancers in the US

UNC Lineberger among national leaders endorsing goal of eliminating HPV-related cancers in the US

The directors of the 70 National Cancer Institute-designated cancer centers, including UNC Lineberger Comprehensive Cancer Center, have issued a joint statement endorsing gender-neutral HPV vaccination and evidence-based cancer screening.

UNC Lineberger among national leaders endorsing goal of eliminating HPV-related cancers in the US - Read More…

More frequent screening after prostate cancer treatment not linked to improved survival

More frequent screening after prostate cancer treatment not linked to improved survival

A study by UNC Lineberger's Ronald Chen, MD, MPH, and colleagues assessed whether monitoring prostate cancer patients following treatment with a PSA test every three months versus once a year would provide a long-term survival benefit.

More frequent screening after prostate cancer treatment not linked to improved survival - Read More…

Blood mutations could contaminate genetic analyses of tumors

Blood mutations could contaminate genetic analyses of tumors

UNC Lineberger Comprehensive Cancer Center researchers and colleagues led by Catherine C. Coombs, MD, show that blood cell mutations accounted for as many as 8 percent of the mutations identified in large-scale genetic sequencing efforts at two major academic centers.

Blood mutations could contaminate genetic analyses of tumors - Read More…

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