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Researchers link gene expression patterns of normal tissue to breast cancer prognosis
In the journal npj Breast Cancer, researchers reported they identified a particular gene expression pattern in normal-appearing breast tissue around tumors that was linked to lower 10-year survival rates for women with estrogen receptor-positive breast cancer.
Located in Biochemistry and Biophysics News / / 2016 / May
Mohlke, Garcia-Martinez named Smithies Investigators
The UNC School of Medicine selected professors from the departments of medicine and genetics for the annual award in honor of Oliver Smithies, UNC’s first Nobel Prize winner.
Located in Biochemistry and Biophysics News / / 2016 / July
Biology discovery: tight DNA packaging protects against ‘jumping genes,’ potential cellular destruction
UNC study indicates that the “heterochromatin” form of DNA packaging mainly guards against virus-like genetic elements that destroy genes and destabilize the genome, a precursor of disease.
Located in Biochemistry and Biophysics News / / 2016 / September
UNC researchers identify how hepatitis A virus causes liver injury
A new report in the journal Science describes how the virus can jump species, including to mice – a finding that has major implications for researching the disease and host immune responses to the virus. Jason Whitmire, PhD, and Stanley Lemon, MD, led the research team.
Located in Biochemistry and Biophysics News / / 2016 / September
Komen recognizes Charles Perou with the Brinker Award, its top scientific honor
Susan G. Komen announced UNC Lineberger researcher Charles M. Perou, PhD, as the recipient of this year's Brinker Award for Scientific Distinction in Basic Science for his contributions to the understanding of breast cancer as distinct molecular subtypes that have prognostic value using cutting-edge cancer genomics tools.
Located in Biochemistry and Biophysics News / / 2016 / October
UNC’s Purvis earns NIH Director’s New Innovator Award
With a focus on stem cells, Jeremy Purvis, PhD, wants to tap the power of computer modeling to develop regenerative medicine solutions to medical conditions.
Located in Biochemistry and Biophysics News / / 2016 / October
Researchers find two distinct genetic subtypes in Crohn’s disease patients
The UNC School of Medicine discovery could lead to more effective, personalized treatments for the debilitating gastrointestinal condition.
Located in Biochemistry and Biophysics News / / 2016 / October
Evans co-authors commentary in JAMA
UNC Lineberger Comprehensive Cancer Center member Jim Evans, MD, PhD, Bryson Distinguished Professor of Genetics and Medicine and director of clinical cancer genetics, has co-authored a commentary in the Journal of the American Medical Association (JAMA) on proposed US Food and Drug Administration (FDA) regulation of genetic testing.
Located in Biochemistry and Biophysics News / / 2015 / January
Women who experience postpartum depression symptoms before giving birth may face greater risk
Postpartum depression (PPD) may have a diverse clinical presentation and this has critical implications for diagnosis, treatment and understanding the underlying biology of the illness, a new study finds.
Located in Biochemistry and Biophysics News / / 2015 / January
Researchers pinpoint two genes that trigger severest form of ovarian cancer
UNC geneticists led by Terry Magnuson, PhD, and Ron Chandler, PhD, create the first mouse model of ovarian clear cell carcinoma; show how a known drug can suppress tumor growth.
Located in Biochemistry and Biophysics News / / 2015 / January