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UNC researchers link aging to cellular interactions that occur across generations
Shawn Ahmed, PhD, shows that tweaking specific cellular mechanisms helps tiny worms overcome infertility through a pathway of cellular interactions that result in long life. The finding gives clues to how the molecular interactions in cells of one organism affect progeny many generations later.
Located in News / 2014 / April
UNC researchers pinpoint new role for enzyme in DNA repair, kidney cancer
The discovery, from the lab of Brian Strahl, PhD, offers insights for the creation of better, more targeted therapies for various forms of cancer.
Located in News / 2014 / June
The Signal and the Noise
Henrik Dohlman, PhD, discovered why seemingly identical cells might react differently to the chemical signals inside our bodies and the drugs we use to battle diseases.
Located in News / 2014 / July
UNC researchers find final pieces to the circadian clock puzzle
Sixteen years after scientists found the genes that control the circadian clock in all cells, the lab of UNC’s Aziz Sancar, MD, PhD, discovered the mechanisms responsible for keeping the clock in sync.
Located in News / 2014 / September
UNC researchers link gene to increased dendritic spines – a signpost of autism
By deleting the NrCAM gene, scientists have found a potential way to cut back on the neural connections implicated in Autism Spectrum Disorder.
Located in News / 2014 / September
All the Cell’s a Stage
Brian Strahl, PhD, and his band of biochemists unravel the complicated mysteries of the epigenetic code to find a culprit in cancer development.
Located in News / 2014 / October
Molecular twist helps regulate the cellular message to make histone proteins
In a collaborative effort published online in the January 18, 2013 issue of the journal Science, researchers at the University of North Carolina and Columbia University show for the first time how two key proteins in messenger RNA communicate via a molecular twist to help maintain the balance of histones to DNA.
Located in News / 2013 / January
UNC researchers discover the underlying mechanisms behind chronic inflammation-associated diseases
A team lead by Xian Chen of UNC mapped the complex interactions of proteins that control inflammation at the molecular level.
Located in News / 2013 / February
Researchers identify genetic sequence that helps to coordinate synthesis of DNA-packaging proteins
Research conducted in fruit flies at the University of North Carolina School of Medicine has pinpointed a specific DNA sequence that both triggers the formation of the “histone locus body” and turns on all the histone genes in the entire block.
Located in News / 2013 / March
UNC researchers engineer 'protein switch' to dissect role of cancer’s key players
In the first application of this approach, the UNC researchers showed how a protein called Src kinase influences the way cells extend and move, a previously unknown role that is consistent with the protein’s ties to tumor progression and metastasis.
Located in News / 2013 / April