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UNC researchers engineer 'protein switch' to dissect role of cancer’s key players
In the first application of this approach, the UNC researchers showed how a protein called Src kinase influences the way cells extend and move, a previously unknown role that is consistent with the protein’s ties to tumor progression and metastasis.
Located in Biochemistry and Biophysics News / / 2013 / April
Researchers identify genetic sequence that helps to coordinate synthesis of DNA-packaging proteins
Research conducted in fruit flies at the University of North Carolina School of Medicine has pinpointed a specific DNA sequence that both triggers the formation of the “histone locus body” and turns on all the histone genes in the entire block.
Located in Biochemistry and Biophysics News / / 2013 / March
CURE Ocular Melanoma (CURE OM) awards grant to develop treatments for uveal melanoma
A research team directed by Professors John Sondek, PhD, UNC School of Medicine and William Janzen, UNC Eshelman School of Pharmacy, has been awarded a two-year grant from the Community United for Research and Education of Ocular Melanoma (CURE OM) to identify inhibitors of an oncogene found in the majority of melanomas of the eye.
Located in Vital Signs / 2013 / March 14
UNC researchers discover the underlying mechanisms behind chronic inflammation-associated diseases
A team lead by Xian Chen of UNC mapped the complex interactions of proteins that control inflammation at the molecular level.
Located in Biochemistry and Biophysics News / / 2013 / February
Art of Science Competition sponsored in conjunction with Carolina Biosciences Alumni Reunion and Symposium
Carolina Biosciences Alumni Reunion and Symposium is sponsoring an Art of Science Competition open to all UNC students, staff and faculty. Winners will get to have their art on display at the Ackland Art Museum.
Located in Vital Signs / 2013 / Feb. 21
Carolina Biosciences Alumni Reunion and Symposia slated for May 16 and 17
The School of Medicine Office of Graduate Education and the Biological Biomedical Sciences Program are sponsoring a reunion for biosciences graduate alumni from 14 member PhD programs from the School of Medicine, College of Arts and Sciences, School of Pharmacy, and School of Dentistry.
Located in Vital Signs / 2013 / Feb. 14
Molecular twist helps regulate the cellular message to make histone proteins
In a collaborative effort published online in the January 18, 2013 issue of the journal Science, researchers at the University of North Carolina and Columbia University show for the first time how two key proteins in messenger RNA communicate via a molecular twist to help maintain the balance of histones to DNA.
Located in Biochemistry and Biophysics News / / 2013 / January
UNC research uncovers new insight into cell development and cancer
The study, published December 27, 2012 by the journal Molecular Cell, implicates a unique class of proteins called polycomb-like proteins, or PCL's, as bridging molecules between the "on" and "off" state of a gene.
Located in Biochemistry and Biophysics News / / 2012 / December
Scientists find missing link between players in the epigenetic code
New research from UNC has established a new link between two fundamental epigenetic tags -- histone H3 lysine 9 methylation and DNA methylation -- in humans.
Located in Biochemistry and Biophysics News / / 2012 / September
Cell death mystery yields new suspect for cancer drug development
A mysterious form of cell death, coded in proteins and enzymes, led to a discovery by UNC researchers uncovering a prime suspect for new cancer drug development.
Located in Biochemistry and Biophysics News / / 2012 / September