![Hepatitus A virus particles (pink) trapped in lysosomes (yellow intracellular organelles), unable to initiate replication in the cytoplasm of cells due to UCGC enzyme being knocked out. (Maryna Kapustina, PhD)](https://news.unchealthcare.org/wp-content/uploads/sites/1159/2020/08/researchers-discover-key-player-in-hepatitis-a-virus-infection-image2-600x480.jpeg)
May 26, 2020
Researchers Discover Key Player in Hepatitis A Virus Infection
The UNC School of Medicine lab of Stanley M. Lemon, MD, and colleagues used CRISPR-Cas9 gene editing to pinpoint a sugar-fatty acid molecule that acts like a gatekeeper to hepatitis A virus infection of human cells.