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MHI Seminar Series presents Jonathan Brown, MD, Riven Family Director of Experimental Biology at Vanderbilt University Medical Center

Summary of Seminar:  Combinatorial signaling by proinflammatory cytokines synergizes to exacerbate toxicity to cells and tissue injury in both acute and chronic cardiovascular disease. To explore synergism at the gene regulatory level, we investigated the dynamics of transcription and chromatin signaling in response to dual cytokines by integrating nascent RNA imaging mass spectrometry, RNA-sequencing, amplification-independent … Read more